Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jonathon M. Sullivan"'
Autor:
Changya Peng, Jamie Y. Ding, Jonathon M. Sullivan, Murali Guthikonda, Paul Fu, Yuchuan Ding, Karam Asmaro
Publikováno v:
Neuroscience Research. 76:93-97
In recent studies, acute ethanol administration appears to play a neuroprotective role during ischemic stroke. We sought to confirm these findings by identifying if ethanol-derived neuroprotection is associated with a reduction in apoptosis. Ethanol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ebf421906cb6ba72a351a3a1bfc55f0
https://doi.org/10.1016/j.neures.2013.02.011
https://doi.org/10.1016/j.neures.2013.02.011
Autor:
Anthony Lagina, Michael Deogracias, Danielle Bazzi, Karin Reed, Lesley Foster, Rasika Chepuri, Jonathon M. Sullivan
Publikováno v:
Academic Emergency Medicine. 19:402-408
ACADEMIC EMERGENCY MEDICINE 2012; 19: 402–408 © 2012 by the Society for Academic Emergency Medicine Abstract Background: Physical and molecular mechanisms for the neuroprotective effect of therapeutic hypothermia are not completely understood, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6880d7acaaa0d5a0c8539df288f2f100
https://doi.org/10.1111/j.1553-2712.2012.01326.x
https://doi.org/10.1111/j.1553-2712.2012.01326.x
Autor:
Yu Wang, Xunming Ji, Xiaokun Geng, Yuchuan Ding, Jamie Y. Ding, Changya Peng, Jonathon M. Sullivan, Karam Asmaro, Fei Wang
Publikováno v:
Stroke. 43:205-210
Background and Purpose— Ethanol consumption is inversely associated with the risk of ischemic stroke, suggesting a neuroprotective effect. In a rat model of transient cerebral ischemia, we identified ethanol as a possible treatment for acute ischem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343ff3e662b080d0254966acc3777151
https://doi.org/10.1161/strokeaha.111.629576
https://doi.org/10.1161/strokeaha.111.629576
Autor:
Gary S. Krause, Jonathon M. Sullivan, Rita Kumar, Andrea B. Page, Thomas H. Sanderson, Alina C. Murariu-Dobrin
Publikováno v:
Neurological Research. 31:947-958
Insulin is neuroprotective following transient global brain ischemia; however, the mechanisms by which insulin exerts its salutary effects remain unclear.We assessed insulin's effect on the PI3K-Akt survival system and consequent modulation of the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d490f53a29190a5b30cc444f56f3997
https://doi.org/10.1179/174313209x382449
https://doi.org/10.1179/174313209x382449
Publikováno v:
Journal of Neurochemistry. 106:1248-1258
The critical event of the intrinsic pathway of apoptosis following transient global brain ischemia is the release of cytochrome c from the mitochondria. In vitro studies have shown that insulin can signal specifically via phosphatidylinositol-3-OH-ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e9d964d3c0d37c2aa69a683ed14a19
https://doi.org/10.1111/j.1471-4159.2008.05473.x
https://doi.org/10.1111/j.1471-4159.2008.05473.x
Autor:
Jonathon M. Sullivan, Brian J. O'Neil
Publikováno v:
Therapy. 8:673-675
Recent advances in cardiac arrest resuscitation, especially therapeutic hypothermia, have begun a paradigm shift in our approach to these patients, as underscored in the recent International Liaison Committee on Resuscitation guidelines [1]. The pros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f956b85a8ba413c873b59a4400d60e2
https://doi.org/10.2217/thy.11.73
https://doi.org/10.2217/thy.11.73
Autor:
Gary S. Krause, Donald J. DeGracia, Robert W. Neumar, José A. Rafols, Lawrence I. Grossman, Blaine C. White, Brian J. O'Neil, Jonathon M. Sullivan
Publikováno v:
Journal of the Neurological Sciences. 179:1-33
Brain ischemia and reperfusion engage multiple independently-fatal terminal pathways involving loss of membrane integrity in partitioning ions, progressive proteolysis, and inability to check these processes because of loss of general translation com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a15cd5664009069200a8fc9b3be231
https://doi.org/10.1016/s0022-510x(00)00386-5
https://doi.org/10.1016/s0022-510x(00)00386-5
Autor:
José A. Rafols, Gary S. Krause, Katie R. Hikade, Nabil J. Bahu, Sarah S. Alousi, Jonathon M. Sullivan, Blaine C. White
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 19:1010-1019
Brain reperfusion causes prompt, severe, and prolonged protein synthesis suppression and increased phosphorylation of eukaryotic initiation factor 2α [eIF2α(P)] in hippocampal CA1 and hilar neurons, The authors hypothesized that eIF2α(P) dephospho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3921ed59df4f26cab229975ddefaa4c1
https://doi.org/10.1097/00004647-199909000-00009
https://doi.org/10.1097/00004647-199909000-00009
Autor:
Joel E. Pittman, Jonathon M. Sullivan, Robert W. Neumar, Blaine C. White, Gary S. Krause, Katie R. Hikade, Donald J. DeGracia, José A. Rafols, Sarah S. Alousi
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 17:1291-1302
Postischemic brain reperfusion is associated with a substantial and long-lasting reduction of protein synthesis in selectively vulnerable neurons. Because the overall translation initiation rate is typically regulated by altering the phosphorylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282293393703bb84243d8d78253d259f
https://doi.org/10.1097/00004647-199712000-00004
https://doi.org/10.1097/00004647-199712000-00004
Autor:
Michael Deogracias, Jonathon M. Sullivan, Joseph M. Wider, Thomas H. Sanderson, Anthony Lagina, Rita Kumar, Lesley Calo
Publikováno v:
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 20(4)
Objectives Hypothermia has a well-established neuroprotective effect and offers a foundation for combination therapy for brain ischemia. The authors evaluated the effect of combination therapy with insulin-like growth factor-1 (IGF-1) and hypothermia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18dfc6252f39fff239a3883f8fda06c0
https://pubmed.ncbi.nlm.nih.gov/23701341
https://pubmed.ncbi.nlm.nih.gov/23701341