Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jonathon M. Muncie"'
Autor:
Ashley RG Libby, David A Joy, Po-Lin So, Mohammad A Mandegar, Jonathon M Muncie, Federico N Mendoza-Camacho, Valerie M Weaver, Bruce R Conklin, Todd C McDevitt
Publikováno v:
eLife, Vol 7 (2018)
Morphogenesis involves interactions of asymmetric cell populations to form complex multicellular patterns and structures comprised of distinct cell types. However, current methods to model morphogenic events lack control over cell-type co-emergence a
Externí odkaz:
https://doaj.org/article/f96a0f62c79f4d14993cf3909712610d
Using four-dimensional whole-embryo light sheet imaging with improved and accessible computational tools, we longitudinally reconstruct early murine cardiac development at single-cell resolution. Nascent mesoderm progenitors form opposing density and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c0e1d2015a170fd78b8a03decd7ed63
https://doi.org/10.1101/2022.08.01.502159
https://doi.org/10.1101/2022.08.01.502159
Autor:
Swetansu K. Hota, Kavitha S. Rao, Andrew P. Blair, Ali Khalilimeybodi, Kevin M. Hu, Reuben Thomas, Kevin So, Vasumathi Kameswaran, Jiewei Xu, Benjamin J. Polacco, Ravi V. Desai, Nilanjana Chatterjee, Austin Hsu, Jonathon M. Muncie, Aaron M. Blotnick, Sarah A. B. Winchester, Leor S. Weinberger, Ruth Hüttenhain, Irfan S. Kathiriya, Nevan J. Krogan, Jeffrey J. Saucerman, Benoit G. Bruneau
Publikováno v:
Nature, vol 602, iss 7895
Nature
Nature
Differentiation proceeds along a continuum of increasingly fate-restricted intermediates, referred to as canalization1,2. Canalization is essential for stabilizing cell fate, but the mechanisms that underlie robust canalization are unclear. Here we s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ae0b4e37cc5b8489fdcac679c42706
https://escholarship.org/uc/item/0s20m15c
https://escholarship.org/uc/item/0s20m15c
Publikováno v:
Cell. 186:479-496.e23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e428e653d89401826a96d646c0e92a9
https://doi.org/10.1016/j.cell.2023.01.001
https://doi.org/10.1016/j.cell.2023.01.001
Publikováno v:
Dev Cell
Developmental cell, vol 56, iss 13
Developmental cell, vol 56, iss 13
Cells in tissues experience a plethora of forces that regulate their fate and modulate development and homeostasis. Cells sense mechanical cues through localized mechanoreceptors or by influencing cytoskeletal or plasma membrane organization. Cells t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33aa82642c5406d034faf67815be8ab5
https://europepmc.org/articles/PMC9056158/
https://europepmc.org/articles/PMC9056158/
Autor:
Valerie M. Weaver, Andrew S. Moore, Danielle L. Swaney, Jonathon M. Muncie, Andrew Dillin, Alexander R. Dunn, Carlos Garzon-Coral, Kuei-Ho Chen, Breanna Ford, Catherine Schneider, Joseph R. Daniele, Hao Shao, Marc Hellerstein, Sagar S. Manoli, Phillip A. Frankino, Daniel K. Nomura, Jason E. Gestwicki, Kevin M. Tharp, Gregory M. Ku, Greg A. Timblin, Nevan J. Krogan, Karou Saijo, Connor Stashko, Alicia L. Richards, Ryo Higuchi-Sanabria
Publikováno v:
Cell Metab
Cell metabolism, vol 33, iss 7
Cell metabolism, vol 33, iss 7
Mitochondria control eukaryotic cell fate by producing the energy needed to support life and the signals required to execute programmed cell death. The biochemical milieu is known to affect mitochondrial function and contribute to the dysfunctional m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d282d1f17247429a757bdd49f294f249
https://europepmc.org/articles/PMC8266765/
https://europepmc.org/articles/PMC8266765/
Autor:
Jonathon M. Muncie, Valerie M. Weaver, Zev J. Gartner, Vasudha Srivastava, Jeffrey O. Bush, Abigail A. Kindberg
Publikováno v:
The Journal of Cell Biology
The Journal of cell biology, vol 220, iss 6
The Journal of cell biology, vol 220, iss 6
How EPH/EPHRIN signaling regulates the biophysical properties of cells to drive tissue organization is not well understood. Kindberg et al. find that EPH/EPHRIN signaling drives cellular organization by modulating cell contact strength by regulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b69a34c0a2a40a4ceb740d2f71e9c4
https://pubmed.ncbi.nlm.nih.gov/33999116
https://pubmed.ncbi.nlm.nih.gov/33999116
Publikováno v:
SSRN Electronic Journal.
Embryogenesis is directed by morphogens that induce differentiation within a defined tissue geometry. Tissue organization is mediated by cell-cell and cell-extracellular matrix (ECM) adhesions and is modulated by cell tension and tissue-level force.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ef7281bb56b3c7b738b57fbef9c77a
https://doi.org/10.2139/ssrn.3543833
https://doi.org/10.2139/ssrn.3543833
Autor:
Jonathon M. Muncie, Valerie M. Weaver
Publikováno v:
Cell Stem Cell. 28:175-176
In this issue of Cell Stem Cell, De Belly et al. (2021) and Bergert et al. (2021) reveal that membrane tension regulates the pluripotent state via endocytosis-mediated ERK signaling. These findings advance our understanding of naive pluripotency and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d3f3f4a7f1931aebf73fc01a8bef358
https://doi.org/10.1016/j.stem.2021.01.008
https://doi.org/10.1016/j.stem.2021.01.008
Autor:
Jonathon M. Muncie, Valerie M. Weaver, Lydia L. Sohn, Johnathon N. Lakins, Roberto Falcón-Banchs
Publikováno v:
Journal of visualized experiments : JoVE, vol 2019, iss 151
J Vis Exp
J Vis Exp
Human embryonic stem cells demonstrate a unique ability to respond to morphogens in vitro by self-organizing patterns of cell fate specification that correspond to primary germ layer formation during embryogenesis. Thus, these cells represent a power
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636d461ca4c5ee9f6be4ff9b5edd8fb3
https://escholarship.org/uc/item/6r51g9bk
https://escholarship.org/uc/item/6r51g9bk