Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jonathon J. Hirst"'
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
Preterm birth is known to cause impaired cerebellar development, and this is associated with the development of neurobehavioral disorders. This review aims to identify the mechanisms through which preterm birth impairs cerebellar development and cons
Externí odkaz:
https://doaj.org/article/2a64ea2602804c018ed7a8c20c0f7bd1
Publikováno v:
Neuroendocrinology. 88:287-292
Background/Aims: Allopregnanolone suppresses central nervous system activity and has neuroprotective actions in hypoxia-induced brain injury. In pregnant sheep allopregnanolone concentrations are high during fetal life and decline rapidly after birth
Autor:
Roger Smith, Dirk F. van Helden, M.A. Read, Helena C. Parkington, Eng-Cheng Chan, Dimitris K. Grammatopoulos, Jonathon J Hirst, Hannah K. Palliser, Richard C. Nicholson, Tamas Zakar
Publikováno v:
The Australian and New Zealand Journal of Obstetrics and Gynaecology. 47:430-437
The physiological processes that regulate the onset of parturition and birth are slowly being elucidated, and the points at which pathology can intervene are becoming more apparent. The data support the view that multiple pathways lead to myometrial
Publikováno v:
Neuroscience. 146(4)
Allopregnanolone (AP) is a potent GABAergic agonist that suppresses CNS activity, seizure threshold, and excitotoxicity in the adult brain. AP is present in the fetal sheep brain and increases rapidly after asphyxial insult due to increased 5alpha-re