Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jonathon J. Graham"'
Autor:
Marta Vuerich, Na Wang, Jonathon J. Graham, Li Gao, Wei Zhang, Ahmadreza Kalbasi, Lina Zhang, Eva Csizmadia, Jason Hristopoulos, Yun Ma, Efi Kokkotou, Adam S. Cheifetz, Simon C. Robson, Maria Serena Longhi
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Unconjugated bilirubin modulates Th17-cell metabolism in Crohn’s disease by limiting glycolysis and through downregulation of phosphoglycerate-kinase-1 (PGK1) and aldolase-A (ALDOA).
Externí odkaz:
https://doaj.org/article/10ccf70848ef46e185bfb5e604e4241c
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101156- (2022)
Summary: Here we present an optimized protocol for transcriptome profiling of COVID-19 patient samples, including peripheral blood mononuclear cells (PBMCs) and formalin-fixed paraffin-embedded tissue samples obtained from the lung, liver, heart, kid
Externí odkaz:
https://doaj.org/article/5d1fe0e0fecd44189bd97806e1518084
Autor:
Na Wang, Marta Vuerich, Ahmadreza Kalbasi, Jonathon J. Graham, Eva Csizmadia, Zachary James Manickas-Hill, Ann Woolley, Clement David, Eric M. Miller, Kara Gorman, Jonathan L. Hecht, Shahzad Shaefi, Simon C. Robson, Maria Serena Longhi
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103205- (2021)
Summary: T cell exhaustion and dysfunction are hallmarks of severe COVID-19. To gain insights into the pathways underlying these alterations, we performed a comprehensive transcriptome analysis of peripheral-blood-mononuclear-cells (PBMCs), spleen, l
Externí odkaz:
https://doaj.org/article/03da945e58204d69bd6bcc6513eaad77
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Autoimmune hepatitis (AIH) is a chronic inflammatory disorder characterized by hypergammaglobulinemia, presence of serum autoantibodies and histological features of interface hepatitis. AIH therapeutic management still relies on the administration of
Externí odkaz:
https://doaj.org/article/ee46cb7bdcec4a28b066482edda1d957
Autor:
Marta Vuerich, Ahmadreza Kalbasi, Eric M. Miller, Na Wang, Simon C. Robson, Eva Csizmadia, Ann E. Woolley, Jonathon J. Graham, Zachary Manickas-Hill, Kara Gorman, Maria Serena Longhi, Clément N. David, Jonathan L. Hecht, Shahzad Shaefi
Publikováno v:
iScience
iScience, Vol 24, Iss 10, Pp 103205-(2021)
iScience, Vol 24, Iss 10, Pp 103205-(2021)
T cell exhaustion and dysfunction are hallmarks of severe COVID-19. To gain insights into the pathways underlying these alterations, we performed a comprehensive transcriptome analysis of peripheral-blood-mononuclear-cells (PBMCs), spleen, lung, kidn
Autor:
Ma Y; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom., Su H; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.; Department of Liver Disease of Chinese PLA General Hospital, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China., Yuksel M; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.; Koc University Research Centre for Translational Medicine, Istanbul, Turkey., Longhi MS; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.; Department of Anesthesia, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., McPhail MJ; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom., Wang P; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom., Bansal S; Paediatric Liver, GI and Nutrition Centre, King's College Hospital, London, United Kingdom., Wong GW; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.; Department of Medicine, Ng Teng Fong General Hospital, Singapore., Graham J; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom., Yang L; Department of Gastroenterology & Hepatology, West China Hospital, Sichuan University, Chengdu, China., J Thompson R; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.; Paediatric Liver, GI and Nutrition Centre, King's College Hospital, London, United Kingdom., Doherty DG; Discipline of Immunology, School of Medicine, Trinity College Dublin, Dublin, Ireland., Hadzic N; Paediatric Liver, GI and Nutrition Centre, King's College Hospital, London, United Kingdom., Zen Y; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom., Quaglia A; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.; Department of Cellular Pathology, Royal Free London NHS Foundation Trust, UCL Cancer Institute, Research Department of Pathology, London, United Kingdom., Heneghan MA; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom., Samyn M; Paediatric Liver, GI and Nutrition Centre, King's College Hospital, London, United Kingdom., Vergani D; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom., Mieli-Vergani G; Institute of Liver Studies, MowatLabs, Department of Inflammation Biology, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.; Paediatric Liver, GI and Nutrition Centre, King's College Hospital, London, United Kingdom.
Publikováno v:
Hepatology (Baltimore, Md.) [Hepatology] 2021 Oct; Vol. 74 (4), pp. 2032-2046. Date of Electronic Publication: 2021 Jun 21.
Autor:
Liberal R; Department of Liver Studies, Division of Transplantation Immunology & Mucosal Biology, MRC Centre for Transplantation, Faculty of Life Sciences & Medicine, King's College London, London, UK.; Gastroenterology Department, Centro Hospitalar São João, Faculty of Medicine of the University of Porto, Porto, Portugal., Grant CR; Department of Liver Studies, Division of Transplantation Immunology & Mucosal Biology, MRC Centre for Transplantation, Faculty of Life Sciences & Medicine, King's College London, London, UK., Yuksel M; Department of Liver Studies, Division of Transplantation Immunology & Mucosal Biology, MRC Centre for Transplantation, Faculty of Life Sciences & Medicine, King's College London, London, UK., Graham J; Department of Liver Studies, Division of Transplantation Immunology & Mucosal Biology, MRC Centre for Transplantation, Faculty of Life Sciences & Medicine, King's College London, London, UK., Kalbasi A; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA., Ma Y; Department of Liver Studies, Division of Transplantation Immunology & Mucosal Biology, MRC Centre for Transplantation, Faculty of Life Sciences & Medicine, King's College London, London, UK., Heneghan MA; Department of Liver Studies, Division of Transplantation Immunology & Mucosal Biology, MRC Centre for Transplantation, Faculty of Life Sciences & Medicine, King's College London, London, UK., Mieli-Vergani G; Department of Liver Studies, Division of Transplantation Immunology & Mucosal Biology, MRC Centre for Transplantation, Faculty of Life Sciences & Medicine, King's College London, London, UK.; MowatLabs Paediatric Liver, GI & Nutrition Centre, Faculty of Life Sciences & Medicine, King's College London, London, UK., Vergani D; Department of Liver Studies, Division of Transplantation Immunology & Mucosal Biology, MRC Centre for Transplantation, Faculty of Life Sciences & Medicine, King's College London, London, UK., Longhi MS; Department of Liver Studies, Division of Transplantation Immunology & Mucosal Biology, MRC Centre for Transplantation, Faculty of Life Sciences & Medicine, King's College London, London, UK.; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Publikováno v:
Hepatology (Baltimore, Md.) [Hepatology] 2017 Nov; Vol. 66 (5), pp. 1570-1584. Date of Electronic Publication: 2017 Oct 03.