Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jonathon Hinton"'
Autor:
Richard Wooster, P. Andrew Futreal, Michael R. Stratton, David N. Louis, Tracy T. Batchelor, Wolf Mueller, Kymberly K. Levine, Jennifer E. Roy, Gregory Riggins, Douglas F. Easton, Andy Yates, Sara Widaa, Sofie West, Jennifer Varian, Calli Tofts, Helen Solomon, Alexandra Small, Rebecca Shepherd, David Richardson, Keiran Raine, Robert Petty, Janet Perry, Andrew Menzies, Richard Lugg, Ross Laman, Vivienne Kosmidou, David Jones, Andy Jenkinson, Jonathon Hinton, Katy Hills, Rachel Harrison, Kelly Halliday, Kristian Gray, Matthew Gorton, Simon Forbes, Ed Dicks, Jennifer Cole, Jody Clements, Adam Butler, Gemma Buck, Lisa Brackenbury, Syd Barthorpe, Tim Avis, Adrian Parker, Sarah O'Meara, Helen Davies, Graham Bignell, Sarah Edkins, Chris Greenman, Jon Teague, Claire Stevens, Philip Stephens, Daniel P. Cahill, Raffaella Smith, Chris Hunter
Supplementary Information from A Hypermutation Phenotype and Somatic MSH6 Mutations in Recurrent Human Malignant Gliomas after Alkylator Chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d0e7301459a6795af7b4fc360e50d5
https://doi.org/10.1158/0008-5472.22366754.v1
https://doi.org/10.1158/0008-5472.22366754.v1
Autor:
Richard Wooster, P. Andrew Futreal, Michael R. Stratton, David N. Louis, Tracy T. Batchelor, Wolf Mueller, Kymberly K. Levine, Jennifer E. Roy, Gregory Riggins, Douglas F. Easton, Andy Yates, Sara Widaa, Sofie West, Jennifer Varian, Calli Tofts, Helen Solomon, Alexandra Small, Rebecca Shepherd, David Richardson, Keiran Raine, Robert Petty, Janet Perry, Andrew Menzies, Richard Lugg, Ross Laman, Vivienne Kosmidou, David Jones, Andy Jenkinson, Jonathon Hinton, Katy Hills, Rachel Harrison, Kelly Halliday, Kristian Gray, Matthew Gorton, Simon Forbes, Ed Dicks, Jennifer Cole, Jody Clements, Adam Butler, Gemma Buck, Lisa Brackenbury, Syd Barthorpe, Tim Avis, Adrian Parker, Sarah O'Meara, Helen Davies, Graham Bignell, Sarah Edkins, Chris Greenman, Jon Teague, Claire Stevens, Philip Stephens, Daniel P. Cahill, Raffaella Smith, Chris Hunter
Supplementary Glioma Genes from A Hypermutation Phenotype and Somatic MSH6 Mutations in Recurrent Human Malignant Gliomas after Alkylator Chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843c39d3c59a93addd968798398f0edf
https://doi.org/10.1158/0008-5472.22366757
https://doi.org/10.1158/0008-5472.22366757
Autor:
Richard Wooster, P. Andrew Futreal, Michael R. Stratton, David N. Louis, Tracy T. Batchelor, Wolf Mueller, Kymberly K. Levine, Jennifer E. Roy, Gregory Riggins, Douglas F. Easton, Andy Yates, Sara Widaa, Sofie West, Jennifer Varian, Calli Tofts, Helen Solomon, Alexandra Small, Rebecca Shepherd, David Richardson, Keiran Raine, Robert Petty, Janet Perry, Andrew Menzies, Richard Lugg, Ross Laman, Vivienne Kosmidou, David Jones, Andy Jenkinson, Jonathon Hinton, Katy Hills, Rachel Harrison, Kelly Halliday, Kristian Gray, Matthew Gorton, Simon Forbes, Ed Dicks, Jennifer Cole, Jody Clements, Adam Butler, Gemma Buck, Lisa Brackenbury, Syd Barthorpe, Tim Avis, Adrian Parker, Sarah O'Meara, Helen Davies, Graham Bignell, Sarah Edkins, Chris Greenman, Jon Teague, Claire Stevens, Philip Stephens, Daniel P. Cahill, Raffaella Smith, Chris Hunter
Supplementary Glioma Gene Mutations from A Hypermutation Phenotype and Somatic MSH6 Mutations in Recurrent Human Malignant Gliomas after Alkylator Chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae2ab66f6628c677ca985204a900e72
https://doi.org/10.1158/0008-5472.22366760.v1
https://doi.org/10.1158/0008-5472.22366760.v1
Autor:
Richard Wooster, P. Andrew Futreal, Michael R. Stratton, David N. Louis, Tracy T. Batchelor, Wolf Mueller, Kymberly K. Levine, Jennifer E. Roy, Gregory Riggins, Douglas F. Easton, Andy Yates, Sara Widaa, Sofie West, Jennifer Varian, Calli Tofts, Helen Solomon, Alexandra Small, Rebecca Shepherd, David Richardson, Keiran Raine, Robert Petty, Janet Perry, Andrew Menzies, Richard Lugg, Ross Laman, Vivienne Kosmidou, David Jones, Andy Jenkinson, Jonathon Hinton, Katy Hills, Rachel Harrison, Kelly Halliday, Kristian Gray, Matthew Gorton, Simon Forbes, Ed Dicks, Jennifer Cole, Jody Clements, Adam Butler, Gemma Buck, Lisa Brackenbury, Syd Barthorpe, Tim Avis, Adrian Parker, Sarah O'Meara, Helen Davies, Graham Bignell, Sarah Edkins, Chris Greenman, Jon Teague, Claire Stevens, Philip Stephens, Daniel P. Cahill, Raffaella Smith, Chris Hunter
Malignant gliomas have a very poor prognosis. The current standard of care for these cancers consists of extended adjuvant treatment with the alkylating agent temozolomide after surgical resection and radiotherapy. Although a statistically significan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588bec3d7e4554e771f3e1702e327bb2
https://doi.org/10.1158/0008-5472.c.6495272.v1
https://doi.org/10.1158/0008-5472.c.6495272.v1
Autor:
Benedikt Brors, Hidewaki Nakagawa, Peter J. Campbell, Susanne Gröbner, Natalie Jäger, Jones Dtw, Fujimoto A, Sasithorn Chotewutmontri, Patrick S. Tarpey, Keiran Raine, Matthias Schlesner, Liu Xi, Sophia Derdak, Stefan M. Pfister, Paolo Ribeca, David A. Wheeler, Takafumi N. Yamaguchi, John Douglas Mcpherson, Adam Butler, Jonathon Hinton, Sertier A, Christopher Previti, Peter Lichter, Michael Heinold, Andrey Korshunov, Jon W. Teague, Lawrence E. Heisler, Rolf Kabbe, Robert E. Denroche, Lucy Stebbings, Timothy Beck, Barbara Hutter, Ivo Buchhalter, Andy Menzies, Gut M, Roland Eils, Gut I, Paul C. Boutros, Nicolle Diessl, Lars Feuerbach, Rebecca Shepherd, Sabine Schmidt, Tyler Alioto, Laurie Tonon, Nicholas J. Harding, David T. Jones
As next-generation sequencing becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Through the International Cancer Genome Consortium (ICGC), we compared sequencing pipelines at five indepen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baca1d200f5752d024366421bafc447
https://doi.org/10.1101/013177
https://doi.org/10.1101/013177
Autor:
Mark Maddison, Heather P. Harding, Ming-Qing Du, Athar Aziz, David Bloxham, Kate Hill, Brian J. P. Huntly, Paola Guglielmelli, Charles E. Massie, David G. Kent, Bruce W. S. Robinson, Kim Orchard, Edward Avezov, Gunes Gundem, Nicholas C.P. Cross, Jonathon Hinton, Jyoti Nangalia, P Van Loo, David Ron, L. Mudie, Sarah O’Meara, E J Baxter, Stephen J. Loughran, Anthony R. Green, Christina A. Ortmann, Claire N. Harrison, Clodagh Keohane, David R. Jones, Karoline Kollmann, Anna L. Godfrey, David C. Wedge, D. Dimitropoulou, Inigo Martincorena, M. Bianchi, Alessandro M. Vannucchi, Mel Greaves, Juan Li, Cathy MacLean, Elli Papaemmanuil, Peter J. Campbell, Amy V. Jones, P. S. Tarpey, Keiran Raine, David G. Bowen, Francesca L. Nice, Yvonne Silber, Adam Butler, Jon W. Teague, Sudhir Tauro, J.D. Fitzpatrick, Stuart McLaren, C.T. Goudie
Publikováno v:
The New England Journal of Medicine, 369, 25, pp. 2391-405
The New England Journal of Medicine, 369, 2391-405
The New England Journal of Medicine, 369, 2391-405
Item does not contain fulltext BACKGROUND: Somatic mutations in the Janus kinase 2 gene (JAK2) occur in many myeloproliferative neoplasms, but the molecular pathogenesis of myeloproliferative neoplasms with nonmutated JAK2 is obscure, and the diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac0501a77ea3dce575fb3007c9b5580
https://hdl.handle.net/2066/126260
https://hdl.handle.net/2066/126260
Autor:
Richard Rance, Stuart McLaren, Adam Butler, Jon W. Teague, Serena Nik-Zainal, Andrej Fischer, Ana Cvejic, E J Baxter, Nikhil C. Munshi, M.G. Della Porta, Paresh Vyas, Michael R. Stratton, David T. Bowen, Joannah Score, Carlo Gambacorti-Passerini, Ignacio Varela, KC Anderson, Jonathon Hinton, Charles E. Massie, Helen Davies, Eva Hellström-Lindberg, Andrea Pellagatti, C. McGee, Peter J. Campbell, Anna Gallì, J. S. Wainscoat, Nicholas C.P. Cross, Jacqueline Boultwood, Keiran Raine, Ville Mustonen, David T. Jones, Anna L. Godfrey, Elli Papaemmanuil, Adel K. El-Naggar, I. Rapado, Sudhir Tauro, Peter R. Ellis, Adam Shlien, Erica Travaglino, Michael J. Groves, Anthony R. Green, Phil Stephens, Patrick S. Tarpey, Mario Cazzola, Laura Mudie, Luca Malcovati, Alan J. Warren, P A Futreal
Publikováno v:
ResearcherID
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium.-- et al.
The myelodysplastic syndromes are a heterogeneous group of hematologic cancers characterized by low blood counts, most commonly anemia, and a risk of
The myelodysplastic syndromes are a heterogeneous group of hematologic cancers characterized by low blood counts, most commonly anemia, and a risk of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec55d747dffdc5b32d24289ce263bf77
http://ora.ox.ac.uk/objects/uuid:545532e5-4e3f-4e78-802e-4cf0e0ca4e31
http://ora.ox.ac.uk/objects/uuid:545532e5-4e3f-4e78-802e-4cf0e0ca4e31
Autor:
Panos Deloukas, Sarah Edkins, Helen Davies, Adam Butler, Ciara Fahey, Michael R. Stratton, Sara Widaa, Gillian L. Dalgliesh, Beiyuan Fu, Peter J. Campbell, Calli Latimer, Jenny Andrews, Sajani Swamy, Bin Tean Teh, Jonathon Hinton, Lina Chen, Gemma Buck, Fengtang Yang, David Beare, Graham R. Bignell, P. Andrew Futreal, Christopher Greenman
The cancer genome is moulded by the dual processes of somatic mutation and selection. Homozygous deletions in cancer genomes occur over recessive cancer genes, where they can confer selective growth advantage, and over fragile sites, where they are t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cab298b524491571a5690afe543a85
https://europepmc.org/articles/PMC3145113/
https://europepmc.org/articles/PMC3145113/
Autor:
Claire Stevens, Jody Clements, Katy Hills, Ross Laman, Jennifer E. Roy, David S. Richardson, Jennifer Cole, Sarah Edkins, Christopher Greenman, Kelly Halliday, Sofie West, Helen Davies, Matthew Gorton, Sara Widaa, Richard Wooster, Adam Butler, Richard Lugg, Raffaella Smith, Tracy T. Batchelor, Lisa Brackenbury, Jon W. Teague, Gregory J. Riggins, Andy Jenkinson, Adrian Parker, Syd Barthorpe, Christopher I. Hunter, Simon A. Forbes, Michael R. Stratton, Wolf Mueller, Douglas F. Easton, Janet Perry, Jennifer Varian, Sarah O’Meara, David N. Louis, Helen Solomon, David T. Jones, Ed Dicks, Rachel Harrison, P. Andrew Futreal, Rebecca Shepherd, Philip J. Stephens, Keiran Raine, Tim Avis, Kristian Gray, Gemma Buck, Daniel P. Cahill, Andrew D. Yates, Vivienne Kosmidou, Jonathon Hinton, Robert Petty, Andrew Menzies, Graham R. Bignell, Calli Tofts, Alexandra Small, Kymberly K. Levine
Publikováno v:
Cancer Res
Malignant gliomas have a very poor prognosis. The current standard of care for these cancers consists of extended adjuvant treatment with the alkylating agent temozolomide after surgical resection and radiotherapy. Although a statistically significan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa969034dc593f7ea0e864ded4c8df4
https://europepmc.org/articles/PMC7212022/
https://europepmc.org/articles/PMC7212022/
Autor:
J. Wolter Oosterhuis, Tim Avis, Gemma Buck, Ruud J.H.L.M. van Gurp, Michael R. Stratton, Simon A. Forbes, Richard Wooster, Kelly Halliday, Adam Butler, Raffaella Smith, Philip J. Stephens, Lisa Brackenbury, Jody Clements, Jon W. Teague, Jennifer Cole, Sarah Edkins, Anthony Webb, Katy Hills, Helen Davies, Yvonne Stephens, Keiran Raine, Ed Dicks, Sara Widaa, Claire Stevens, Adrian Parker, Sarah O’Meara, Christopher Greenman, Ross Laman, Christopher I. Hunter, Syd Barthorpe, P. Andrew Futreal, Leendert H. J. Looijenga, Ken Edwards, Rachel Harrison, Rebecca Shepherd, Helen Solomon, Andrew D. Yates, David T. Jones, Kristian Gray, Sofie West, Matthew Gorton, Robert Petty, Andrew Menzies, Ad J. M. Gillis, Vivienne Kosmidou, Janet Perry, Alexandra Small, Jennifer Varian, Jonathon Hinton, Calli Tofts, Graham R. Bignell, Hans Stoop, Richard Lugg
Publikováno v:
Genes Chromosomes & Cancer, 45, 42-46. Wiley-Liss Inc.
Genes Chromosomes Cancer
Genes Chromosomes Cancer
The protein kinase gene family is the most frequently mutated in human cancer. Previous work has documented activating mutations in the KIT receptor tyrosine kinase in testicular germ-cell tumors (TGCT). To investigate further the potential role of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3630a8946fdb34594ed2e0ffa8b95c
https://pure.eur.nl/en/publications/4a08d5f7-ce0c-4fcd-afc7-8c186385ab34
https://pure.eur.nl/en/publications/4a08d5f7-ce0c-4fcd-afc7-8c186385ab34