Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jonathon E Mohl"'
Autor:
Philip Lavretsky, Jonathon E. Mohl, Pär Söderquist, Robert H. S. Kraus, Michael L. Schummer, Joshua I. Brown
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract The translocation of individuals around the world is leading to rising incidences of anthropogenic hybridization, particularly between domestic and wild congeners. We apply a landscape genomics approach for thousands of mallard (Anas platyrh
Externí odkaz:
https://doaj.org/article/41e87a3edbf6417aaa9722216e7dd1be
Autor:
Alice H. Grant, Alejandro C. Rodriguez, Omar J. Rodriguez Moncivais, Shengjie Sun, Lin Li, Jonathon E. Mohl, Ming-Ying Leung, Robert A. Kirken, Georgialina Rodriguez
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6805 (2023)
Overactive Janus kinases (JAKs) are known to drive leukemia, making them well-suited targets for treatment. We sought to identify new JAK-activating mutations and instead found a JAK1-inactivating pseudokinase mutation, V666G. In contrast to other ps
Externí odkaz:
https://doaj.org/article/84091df3a8aa4e85971d479748fbbef7
Autor:
Elisa Robles-Escajeda, Jonathon E. Mohl, Lisett Contreras, Ana P. Betancourt, Bibiana M. Mancera, Robert A. Kirken, Georgialina Rodriguez
Publikováno v:
Viruses, Vol 15, Iss 3, p 658 (2023)
COVID-19, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), remains an ongoing global health challenge. This study analyzed 3641 SARS-CoV-2 positive samples from the El Paso, Texas, community and hospitalized patients over 4
Externí odkaz:
https://doaj.org/article/4c5485917aa64341ab8d8ae95655c34a
Autor:
Elizabeth Stunz, Ned Fetcher, Philip Lavretsky, Jonathon E. Mohl, Jianwu Tang, Michael L. Moody
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Global climate change has resulted in geographic range shifts of flora and fauna at a global scale. Extreme environments, like the Arctic, are seeing some of the most pronounced changes. This region covers 14% of the Earth’s land area, and while ma
Externí odkaz:
https://doaj.org/article/c4017ca9d1ba44848ce6d3ae3a50437a
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 863 (2022)
G protein-coupled receptors (GPCRs) are the largest class of cell-surface receptor proteins with important functions in signal transduction and often serve as therapeutic drug targets. With the rapidly growing public data on three dimensional (3D) st
Externí odkaz:
https://doaj.org/article/d442add9f8fa45eba691421ced9465e3
Autor:
Aleli Campbell, Jonathon E. Mohl, Denisse A. Gutierrez, Armando Varela-Ramirez, Thomas Boland
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Bioprinting technology merges engineering and biological fields and together, they possess a great translational potential, which can tremendously impact the future of regenerative medicine and drug discovery. However, the molecular effects elicited
Externí odkaz:
https://doaj.org/article/9d4e3db883c14cfe8a37f93c18bcad5b
Autor:
Denisse A. Gutierrez, Lisett Contreras, Paulina J. Villanueva, Edgar A. Borrego, Karla Morán-Santibañez, Jessica D. Hess, Rebecca DeJesus, Manuel Larragoity, Ana P. Betancourt, Jonathon E. Mohl, Elisa Robles-Escajeda, Khodeza Begum, Sourav Roy, Robert A. Kirken, Armando Varela-Ramirez, Renato J. Aguilera
Publikováno v:
Cells, Vol 11, Iss 2, p 254 (2022)
In this study, we identified a novel pyrazole-based derivative (P3C) that displayed potent cytotoxicity against 27 human cancer cell lines derived from different tissue origins with 50% cytotoxic concentrations (CC50) in the low micromolar and nanomo
Externí odkaz:
https://doaj.org/article/5cbd8028ab8145fe8e7fc335095f7d64
Publikováno v:
Invertebrate Biology. 142
Publikováno v:
Glycobiology
Mucin-type O-glycosylation is one of the most common posttranslational modifications of proteins. The abnormal expression of various polypeptide GalNAc-transferases (GalNAc-Ts) which initiate and define sites of O-glycosylation are linked to many can
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Tussock cottongrass (Eriophorum vaginatum) is a foundation species for much of the arctic moist acidic tundra, which is currently experiencing extreme effects of climate change. The Arctic is facing higher summer temperatures and extreme weather even