Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Jonathon D. Roybal"'
Autor:
Mark J. Schliekelman, Chad J. Creighton, Brandi N. Baird, Yulong Chen, Priyam Banerjee, Neus Bota-Rabassedas, Young-Ho Ahn, Jonathon D. Roybal, Fengju Chen, Yiqun Zhang, Dhruva K. Mishra, Min P. Kim, Xin Liu, Barbara Mino, Pamela Villalobos, Jaime Rodriguez-Canales, Carmen Behrens, Ignacio I. Wistuba, Samir M. Hanash, Jonathan M. Kurie
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Cancer-associated fibroblasts (CAFs) regulate diverse intratumoral biological programs and can promote or inhibit tumorigenesis, but those CAF populations that negatively impact the clinical outcome of lung cancer patients have not been full
Externí odkaz:
https://doaj.org/article/b98c31b4556442fb996362e7c46fd3c2
Autor:
Jonathan M. Kurie, Mitsuo Yamauchi, Samir M. Hanash, K. Jane Grande-Allen, Jennifer L. West, Mary E. Dickinson, John M. Hicks, Don L. Gibbons, Chad J. Creighton, Ignacio I. Wistuba, Jaime Rodriguez, Edwin Roger Parra Cuentas, Xin Liu, Jonathon D. Roybal, Young-Ho Ahn, Min P. Kim, Tegy J. Vadakkan, Bartley J. Gill, Li Sun, Monica Fahrenholtz, Brandi N. Baird, Mark J. Schliekelman, Masahiko Terajima, Yulong Chen, Daniela Pankova
A Matrigel surface was seeded first with GFP-tagged aggregates followed 24 h later by a CAF single-cell suspension. Time-lapse microscopy was immediately after CAF seeding. Scale bar, 200 μm. Movie compiled at 8 frames per second.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6adc06feb8a0e90434ce55a27f9c815
https://doi.org/10.1158/1541-7786.22512120
https://doi.org/10.1158/1541-7786.22512120
Autor:
Jonathan M. Kurie, Chad J. Creighton, John V. Heymach, Pierre Saintigny, Diane D. Liu, Nishan Thilaganathan, Cristina Alvarez, Brandi N. Baird, Don L. Gibbons, Yanan Yang, Young-Ho Ahn, Yi Zang, Jonathon D. Roybal
PDF file - 57K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fad276ffb1525d2674e5c03fce0f757
https://doi.org/10.1158/1541-7786.22519428.v1
https://doi.org/10.1158/1541-7786.22519428.v1
Autor:
Jonathan M. Kurie, Chad J. Creighton, John V. Heymach, Pierre Saintigny, Diane D. Liu, Nishan Thilaganathan, Cristina Alvarez, Brandi N. Baird, Don L. Gibbons, Yanan Yang, Young-Ho Ahn, Yi Zang, Jonathon D. Roybal
PDF file - 49K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7af6a979da9d0793e22bbeda831cb3
https://doi.org/10.1158/1541-7786.22519434.v1
https://doi.org/10.1158/1541-7786.22519434.v1
Autor:
Jonathan M. Kurie, Chad J. Creighton, John V. Heymach, Pierre Saintigny, Diane D. Liu, Nishan Thilaganathan, Cristina Alvarez, Brandi N. Baird, Don L. Gibbons, Yanan Yang, Young-Ho Ahn, Yi Zang, Jonathon D. Roybal
PDF file - 34K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56421f909bbd6ff97c32342a27a76f70
https://doi.org/10.1158/1541-7786.22519431
https://doi.org/10.1158/1541-7786.22519431
Autor:
Jonathan M. Kurie, Mitsuo Yamauchi, Samir M. Hanash, K. Jane Grande-Allen, Jennifer L. West, Mary E. Dickinson, John M. Hicks, Don L. Gibbons, Chad J. Creighton, Ignacio I. Wistuba, Jaime Rodriguez, Edwin Roger Parra Cuentas, Xin Liu, Jonathon D. Roybal, Young-Ho Ahn, Min P. Kim, Tegy J. Vadakkan, Bartley J. Gill, Li Sun, Monica Fahrenholtz, Brandi N. Baird, Mark J. Schliekelman, Masahiko Terajima, Yulong Chen, Daniela Pankova
A Matrigel surface was seeded first with GFP-tagged aggregates followed 24 h later by a CAF single-cell suspension. Time-lapse microscopy was initiated 24 hours after CAF seeding. Dissociating tumor aggregates migrate toward each other (arrow). Scale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f683823f0756c14a4609cd2607c0368
https://doi.org/10.1158/1541-7786.22512117
https://doi.org/10.1158/1541-7786.22512117
Autor:
Jonathan M. Kurie, Mitsuo Yamauchi, Samir M. Hanash, K. Jane Grande-Allen, Jennifer L. West, Mary E. Dickinson, John M. Hicks, Don L. Gibbons, Chad J. Creighton, Ignacio I. Wistuba, Jaime Rodriguez, Edwin Roger Parra Cuentas, Xin Liu, Jonathon D. Roybal, Young-Ho Ahn, Min P. Kim, Tegy J. Vadakkan, Bartley J. Gill, Li Sun, Monica Fahrenholtz, Brandi N. Baird, Mark J. Schliekelman, Masahiko Terajima, Yulong Chen, Daniela Pankova
Intratumoral collagen cross-links heighten stromal stiffness and stimulate tumor cell invasion, but it is unclear how collagen cross-linking is regulated in epithelial tumors. To address this question, we used KrasLA1 mice, which develop lung adenoca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfbe9b0c7bbf014e842f399f6eca511c
https://doi.org/10.1158/1541-7786.c.6540138.v1
https://doi.org/10.1158/1541-7786.c.6540138.v1
Autor:
Jennifer L. West, Jonathan M. Kurie, Jonathon D. Roybal, Zain H. Rizvi, Jennifer E. Saik, Laila C. Roudsari, Don L. Gibbons, Bartley J. Gill
PDF file - 35K, q-PCR data for several EMT markers shows that TGFbeta induces changes in expression of EMT-related genes in PEG-encapsulated 344SQ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724a85c3586e228f310a3df3014036ac
https://doi.org/10.1158/0008-5472.22396040
https://doi.org/10.1158/0008-5472.22396040
Autor:
Jennifer L. West, Jonathan M. Kurie, Jonathon D. Roybal, Zain H. Rizvi, Jennifer E. Saik, Laila C. Roudsari, Don L. Gibbons, Bartley J. Gill
PDF file - 60K, Immunostaining of PEG-encapsulated structures following TGFbeta treatment shows loss of polar organization and cells undergo random apoptosis and proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862320f65ce72dddaf830540d69b9e85
https://doi.org/10.1158/0008-5472.22396058
https://doi.org/10.1158/0008-5472.22396058
Autor:
Jennifer L. West, Jonathan M. Kurie, Jonathon D. Roybal, Zain H. Rizvi, Jennifer E. Saik, Laila C. Roudsari, Don L. Gibbons, Bartley J. Gill
PDF file - 19K, echanical testing of differently stiff hydrogels with cells encapsulated at Day 1 and Day 12 (compared to acellular) shows no change in mechanical property difference with cell encapsulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0922fb1e21fdc53bb84ea0cb29d477cf
https://doi.org/10.1158/0008-5472.22396067
https://doi.org/10.1158/0008-5472.22396067