Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jonathon A Ditlev"'
Autor:
Vladimir Zhemkov, Jonathon A Ditlev, Wan-Ru Lee, Mikaela Wilson, Jen Liou, Michael K Rosen, Ilya Bezprozvanny
Publikováno v:
eLife, Vol 10 (2021)
Sigma 1 receptor (S1R) is a 223-amino-acid-long transmembrane endoplasmic reticulum (ER) protein. S1R modulates activity of multiple effector proteins and is a well-established drug target. However, signaling functions of S1R in cells are poorly unde
Externí odkaz:
https://doaj.org/article/151f396a8d22489085371cbc83db875d
Autor:
Jonathon A Ditlev, Anthony R Vega, Darius Vasco Köster, Xiaolei Su, Tomomi Tani, Ashley M Lakoduk, Ronald D Vale, Satyajit Mayor, Khuloud Jaqaman, Michael K Rosen
Publikováno v:
eLife, Vol 8 (2019)
During T cell activation, biomolecular condensates form at the immunological synapse (IS) through multivalency-driven phase separation of LAT, Grb2, Sos1, SLP-76, Nck, and WASP. These condensates move radially at the IS, traversing successive radiall
Externí odkaz:
https://doaj.org/article/4967687a42254a76a7c714088eb669a4
Coupling of protein condensates to ordered lipid domains determines functional membrane organization
Autor:
Hong-Yin Wang, Sze Ham Chan, Simli Dey, Ivan Castello-Serrano, Michael K. Rosen, Jonathon A. Ditlev, Kandice R. Levental, Ilya Levental
Publikováno v:
Science Advances. 9
During T-cell activation, the transmembrane adaptor Linker of Activation of T-cells (LAT) forms biomolecular condensates with Grb2 and Sos1, facilitating signaling. LAT has also been associated with cholesterol-rich condensed lipid domains. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400f56614f6b00b8af505ef68197fc84
https://doi.org/10.1126/sciadv.adf6205
https://doi.org/10.1126/sciadv.adf6205
Autor:
Bin Tean Teh, Craig G. Rogers, Arie Belldegrun, Robert Figlin, David Seligson, Robert Amato, Nicholas G. Vogelzang, Walter Stadler, Theresa Nicol, Richard Kahnoski, John Anema, Maria Tretiakova, Michael Pins, Kim Wang, Chunyan Luan, Bin Sing Teh, Puay Hoon Tan, Hiro-omi Kanayama, Masayuki Takahashi, Kyle A. Furge, Kunihiko Futami, Eric J. Kort, Carolina E. Png, Mark W. Betten, Jonathon A. Ditlev, Hyung L. Kim, Min-Han Tan, Ximing J. Yang
Supplementary Figures C1-C2 from A Molecular Classification of Papillary Renal Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755d3e0c0928c447900de6b856bfd0a3
https://doi.org/10.1158/0008-5472.22365210
https://doi.org/10.1158/0008-5472.22365210
Autor:
Bin Tean Teh, Craig G. Rogers, Arie Belldegrun, Robert Figlin, David Seligson, Robert Amato, Nicholas G. Vogelzang, Walter Stadler, Theresa Nicol, Richard Kahnoski, John Anema, Maria Tretiakova, Michael Pins, Kim Wang, Chunyan Luan, Bin Sing Teh, Puay Hoon Tan, Hiro-omi Kanayama, Masayuki Takahashi, Kyle A. Furge, Kunihiko Futami, Eric J. Kort, Carolina E. Png, Mark W. Betten, Jonathon A. Ditlev, Hyung L. Kim, Min-Han Tan, Ximing J. Yang
Supplementary Table 1 from A Molecular Classification of Papillary Renal Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5864b7babe127783d7f3b9cad960482d
https://doi.org/10.1158/0008-5472.22365207
https://doi.org/10.1158/0008-5472.22365207
Autor:
Bin Tean Teh, Craig G. Rogers, Arie Belldegrun, Robert Figlin, David Seligson, Robert Amato, Nicholas G. Vogelzang, Walter Stadler, Theresa Nicol, Richard Kahnoski, John Anema, Maria Tretiakova, Michael Pins, Kim Wang, Chunyan Luan, Bin Sing Teh, Puay Hoon Tan, Hiro-omi Kanayama, Masayuki Takahashi, Kyle A. Furge, Kunihiko Futami, Eric J. Kort, Carolina E. Png, Mark W. Betten, Jonathon A. Ditlev, Hyung L. Kim, Min-Han Tan, Ximing J. Yang
Despite the moderate incidence of papillary renal cell carcinoma (PRCC), there is a disproportionately limited understanding of its underlying genetic programs. There is no effective therapy for metastatic PRCC, and patients are often excluded from k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19db1240b018d748331eb531dbd277ad
https://doi.org/10.1158/0008-5472.c.6494580.v1
https://doi.org/10.1158/0008-5472.c.6494580.v1
Autor:
Atharva Agashe, Steve Chung, Jonathon A. Ditlev, Mitja Drab, Toshifumi Fujioka, Nir S. Gov, Christian Hernandez-Padilla, Hooi Ting Hu, Madlen Hubert, Aleš Iglič, Takeshi Ijuin, Takehiko Inaba, Takanari Inoue, Toshiki Itoh, Suphamon Janewanthanakul, Asami Kawasaki, Manabu Kitamata, Akio Kitao, Veronika Kralj-Iglič, Elin Larsson, Shin Yong Lee, Kang Cheng Liu, Leshani Ahangama Liyanage, Richard Lundmark, Luka Mesarec, Yuko Mimori-Kiyosue, Eiji Morita, Kojiro Mukai, Makoto Nagano, Amrinder S. Nain, Yoshikazu Nakamura, Fubito Nakatsu, Tamako Nishimura, Mitsuo Osuga, Gaddy Rakhaminov, Yoav Ravid, Shiva Razavi, Raj Kumar Sadhu, Takehiko Sasaki, Kei Shigene, Pei Fang Sim, Shiro Suetsugu, Tomohiko Taguchi, Tetsuya Takeda, Kohji Takei, Kazuhiro Takemura, Jiro Toshima, Junko Y. Toshima, Kazuya Tsujita, Yasunori Uchida, Wan Nurul Izzati Wan Mohamad Noor, Naoki Watanabe, Hiroshi Yamada, Hideki Yamaguchi, Yuko Yamamoto, Kazuma Yasuhara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e494f46889fadc8c3ab64b6dd2c746a
https://doi.org/10.1016/b978-0-323-89911-6.00028-5
https://doi.org/10.1016/b978-0-323-89911-6.00028-5
Publikováno v:
RNA
Exciting recent work has highlighted that numerous cellular compartments lack encapsulating lipid bilayers (often called “membraneless organelles”), and that their structure and function are central to the regulation of key biological processes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c011023b1e832f73afe41c54e816763
https://doi.org/10.1261/rna.079026.121
https://doi.org/10.1261/rna.079026.121
Membrane-associated phase separation: organization and function emerge from a two-dimensional milieu
Autor:
Jonathon A. Ditlev
Publikováno v:
Journal of Molecular Cell Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25067efcd17668aeab45f7cb384f963e
https://doi.org/10.1093/jmcb/mjab010
https://doi.org/10.1093/jmcb/mjab010