Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jonathon A, Heier"'
Autor:
Joel M. Serre, Bethany Lucas, Sterling C. T. Martin, Jonathon A. Heier, Xiangqiang Shao, Jeff Hardin
Publikováno v:
Development. 149
The cadherin-catenin complex (CCC) is central to embryonic development and tissue repair, yet how CCC binding partners function alongside core CCC components remains poorly understood. Here, we establish a previously unappreciated role for an evoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75afa5060e8cc64ca6f8a5f6188a331
https://doi.org/10.1242/dev.200775
https://doi.org/10.1242/dev.200775
Autor:
Sun Kyung Kim, Sabine Pokutta, Jonathon A. Heier, William I. Weis, Ian W. Dale, Andrew P. Hinck, Adam V. Kwiatkowski
Publikováno v:
The Journal of Biological Chemistry
α-Catenin binds directly to β-catenin and connects the cadherin–catenin complex to the actin cytoskeleton. Tension regulates α-catenin conformation. Actomyosin-generated force stretches the middle (M)-region to relieve autoinhibition and reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a700325b936258de9cb739688fcd0592
http://europepmc.org/articles/PMC8091058
http://europepmc.org/articles/PMC8091058
Autor:
Andrew P. Hinck, Jonathon A. Heier, Sun Kyung Kim, Adam V. Kwiatkowski, Sabine Pokutta, Willaim I. Weis, Ian W. Dale
Alpha-catenin binds directly to beta-catenin and connects the cadherin-catenin complex to the actin cytoskeleton. Tension regulates alpha-catenin conformation: actomyosin-generated force stretches the middle(M)-region to relieve autoinhibition and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c04e394470df001d611195c27393abdb
https://doi.org/10.1101/2020.10.25.354415
https://doi.org/10.1101/2020.10.25.354415
Autor:
Jonathon A. Heier, Adam V. Kwiatkowski, Hyunook Kang, William I. Weis, Junho Lee, W. James Nelson, Hee Jung Choi, Jeff Hardin, Injin Bang, Kyeong Sik Jin, Xiangqiang Shao, Boyun Lee
Publikováno v:
Journal of Biological Chemistry. 292:7077-7086
Intercellular epithelial junctions formed by classical cadherins, β-catenin, and the actin-binding protein α-catenin link the actin cytoskeletons of adjacent cells into a structural continuum. These assemblies transmit forces through the tissue and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50fb8829fd29ee809b4b2de2ce759ef9
https://doi.org/10.1074/jbc.m116.769778
https://doi.org/10.1074/jbc.m116.769778
Autor:
Chelsea D. Merkel, Ian W. Dale, Emily Diane Wickline, Adam V. Kwiatkowski, Jonathon A. Heier, Donna B. Stolz
Publikováno v:
The Journal of Biological Chemistry
α-Catenin is the primary link between the cadherin·catenin complex and the actin cytoskeleton. Mammalian αE-catenin is allosterically regulated: the monomer binds the β-catenin·cadherin complex, whereas the homodimer does not bind β-catenin but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b17df2c619b68f4ec86464cefd68ae8
http://europepmc.org/articles/PMC4957052
http://europepmc.org/articles/PMC4957052
Publikováno v:
Developmental Dynamics. 244:1300-1312
Background: Whole genome duplication is a useful genetic tool because it allows immediate and complete genetic homozygosity in gynogenetic offspring. A whole genome duplication method in zebrafish, Heat Shock, involves a heat pulse in the period 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27d5686b3a9be3d1f074794d26880b88
https://doi.org/10.1002/dvdy.24315
https://doi.org/10.1002/dvdy.24315
Publikováno v:
Journal of Visualized Experiments : JoVE
Filamentous actin (F-actin) organization within cells is regulated by a large number of actin-binding proteins that control actin nucleation, growth, cross-linking and/or disassembly. This protocol describes a technique - the actin co-sedimentation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3dfa491d24199e6aa354a1698ccef5
https://doi.org/10.3791/55613-v
https://doi.org/10.3791/55613-v
Publikováno v:
Journal of Visualized Experiments.
Manipulation of ploidy allows for useful transformations, such as diploids to tetraploids, or haploids to diploids. In the zebrafish Danio rerio, specifically the generation of homozygous gynogenetic diploids is useful in genetic analysis because it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e571c4b9c8698f82f04438caabc7f5
https://doi.org/10.3791/54492
https://doi.org/10.3791/54492
Autor:
Hyunook, Kang, Injin, Bang, Kyeong Sik, Jin, Boyun, Lee, Junho, Lee, Xiangqiang, Shao, Jonathon A, Heier, Adam V, Kwiatkowski, W James, Nelson, Jeff, Hardin, William I, Weis, Hee-Jung, Choi
Publikováno v:
The Journal of biological chemistry. 292(17)
Intercellular epithelial junctions formed by classical cadherins, β-catenin, and the actin-binding protein α-catenin link the actin cytoskeletons of adjacent cells into a structural continuum. These assemblies transmit forces through the tissue and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::595293930b91a160b6dc1b6a64a90776
https://pubmed.ncbi.nlm.nih.gov/28298447
https://pubmed.ncbi.nlm.nih.gov/28298447