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pro vyhledávání: '"Jonathan Yde"'
Autor:
Jonathan Yde, Stephen Keely, Qi Wu, Johan Fredrik Borg, Natalia Lajczak, Aoife O’Dwyer, Peter Dalsgaard, Robert A Fenton, Hanne Bjerregaard Moeller
Publikováno v:
Frontiers in Nutrition, Vol 3 (2016)
In normal individuals, the epithelium of the colon absorbs 1.5-2 L of water a day to generate dehydrated feces. However, in the condition of bile acid malabsorption (BAM), an excess of bile acids in the colon results in diarrhea. Several studies have
Externí odkaz:
https://doaj.org/article/df8c5177e7de4428bd0616dc9fe58518
Publikováno v:
Yde, J, Wu, Q, Borg, J F, Fenton, R A & Moeller, H B 2022, ' A systems-level analysis of bile acids effects on rat colon epithelial cells ', American Journal of Physiology-Gastrointestinal and Liver Physiology, vol. 322, no. 1, pp. G34-G48 . https://doi.org/10.1152/ajpgi.00178.2021
Bile acid diarrhea is a chronic condition caused by increased delivery of bile acids to the colon. The underlying mechanisms remain to be elucidated. To investigate genes involved in bile acid diarrhea, systems-level analyses were used on a rat bile
Publikováno v:
Yde, J, Keely, S J & Møller, H B 2021, ' Expression, regulation and function of Aquaporin-3 in colonic epithelial cells ', Biochimica et Biophysica Acta-Biomembranes, vol. 1863, no. 7, 183619 . https://doi.org/10.1016/j.bbamem.2021.183619
The human colon balances water and electrolyte absorption and secretion while also forming a barrier protecting the body from the entry of harmful components. Aquaporin-3 (AQP3) is a water, glycerol and H2O2 transporting channel expressed in colonic
Publikováno v:
International Journal of Colorectal Disease. 33:683-694
The growing population of survivors after colon cancer warrants increased attention to the long-term outcome of surgical treatment. The change in bowel anatomy after resection disrupts normal gastrointestinal function and may cause symptoms. Thus, ma
Characterization of AQPs in Mouse, Rat, and Human Colon and Their Selective Regulation by Bile Acids
Autor:
Peter Dalsgaard, Qi Wu, Johan Fredrik Borg, Jonathan Yde, Aoife M. O'Dwyer, Stephen J. Keely, Natalia Lajczak, Robert A. Fenton, Hanne B. Moeller
Publikováno v:
Frontiers in Nutrition
Frontiers in Nutrition, Vol 3 (2016)
Yde, J, Keely, S, Wu, Q, Borg, J F, Lajczak, N, O'Dwyer, A, Dalsgaard, P, Fenton, R A & Moeller, H B 2016, ' Characterization of AQPs in Mouse, Rat, and Human Colon and Their Selective Regulation by Bile Acids ', Frontiers in nutrition, vol. 3, 46 . https://doi.org/10.3389/fnut.2016.00046
Frontiers in Nutrition, Vol 3 (2016)
Yde, J, Keely, S, Wu, Q, Borg, J F, Lajczak, N, O'Dwyer, A, Dalsgaard, P, Fenton, R A & Moeller, H B 2016, ' Characterization of AQPs in Mouse, Rat, and Human Colon and Their Selective Regulation by Bile Acids ', Frontiers in nutrition, vol. 3, 46 . https://doi.org/10.3389/fnut.2016.00046
In normal individuals, the epithelium of the colon absorbs 1.5-2 l of water a day to generate dehydrated feces. However, in the condition of bile acid malabsorption (BAM), an excess of bile acids in the colon results in diarrhea. Several studies have
Autor:
Aoife M. O'Dwyer, Hanne B. Moeller, Jonathan Yde, Natalia Lajczak, Robert A. Fenton, Stephen J. Keely
Publikováno v:
The FASEB Journal. 29
Bile acids (BAs) affect water transport in the colon, as evident in Bile acid malabsorption (BAM). In BAM patients, an increased production of BAs or a decrease in the capacity for BA reabsorption in the ileum cause BAs to overflow into the colon, wh