Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Jonathan Woodsmith"'
Autor:
Manuel Scimeca, Valentina Rovella, Sabrina Caporali, Yufang Shi, Julia Bischof, Jonathan Woodsmith, Giuseppe Tisone, Giuseppe Sica, Ivano Amelio, Gerry Melino, Alessandro Mauriello, Pierluigi Bove
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Renal cell carcinoma originates from the lining of the proximal convoluted renal tubule and represents the most common type of kidney cancer. Risk factors and comorbidities might be associated to renal cell carcinoma, while a small fraction
Externí odkaz:
https://doaj.org/article/c904afa5ec8948d3acd1283ee3170297
Autor:
Mengting Zhu, Valentina Rovella, Manuel Scimeca, Alessandro Mauriello, Yufang Shi, Julia Bischof, Jonathan Woodsmith, Alessandro Anselmo, Gerry Melino, Giuseppe Tisone, Massimiliano Agostini
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide, occurring predominantly in patients with underlying chronic liver disease and cirrhosis. Here, we describe a case of a 62-year-old man that was admi
Externí odkaz:
https://doaj.org/article/e71f761457cc4fd788dcaa1af9f1b8e0
Autor:
Xue Yang, Artem Smirnov, Oreste Claudio Buonomo, Alessandro Mauriello, Yufang Shi, Julia Bischof, Jonathan Woodsmith, TOR CENTRE, Gerry Melino, Eleonora Candi, Francesca Bernassola
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract Here, we present the case of a 47-year-old woman diagnosed with luminal B breast cancer subtype and provide an in-depth analysis of her gene mutations, chromosomal alterations, mRNA and protein expression changes. We found a point mutation i
Externí odkaz:
https://doaj.org/article/10e91730b0314122b32db25daa82b180
Autor:
Roland Bruderer, Marco Tognetti, Lukas Reiter, Ilja E Shapiro, Luca Raess, Tikira Temu, Oliver M Bernhardt, Yuehan Feng, Jonathan Woodsmith
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/a2bd5bb8daa8491185b5dd1be8228905
Autor:
Stefanie Jehle, Natalia Kunowska, Nouhad Benlasfer, Jonathan Woodsmith, Gert Weber, Markus C Wahl, Ulrich Stelzl
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 3, Pp n/a-n/a (2022)
Abstract Protein kinases play an important role in cellular signaling pathways and their dysregulation leads to multiple diseases, making kinases prime drug targets. While more than 500 human protein kinases are known to collectively mediate phosphor
Externí odkaz:
https://doaj.org/article/933ab559b4b04370bec15ae3542245dc
Autor:
Jonathan Poh, Amy H. Ponsford, James Boyd, Jonathan Woodsmith, Ulrich Stelzl, Erich Wanker, Nicholas Harper, David MacEwan, Christopher M. Sanderson
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101686- (2020)
NRF2 (NFE2L2) is a cytoprotective transcription factor associated with >60 human diseases, adverse drug reactions and therapeutic resistance. To provide insight into the complex regulation of NRF2 responses, 1962 predicted NRF2-partner interactions w
Externí odkaz:
https://doaj.org/article/7cf911239b8246beb0bcaf25f01086c0
Autor:
Shuang Yang, Kriti Bahl, Hui-Ting Chou, Jonathan Woodsmith, Ulrich Stelzl, Thomas Walz, Maxence V Nachury
Publikováno v:
eLife, Vol 9 (2020)
Dynamic trafficking of G protein-coupled receptors (GPCRs) out of cilia is mediated by the BBSome. In concert with its membrane recruitment factor, the small GTPase ARL6/BBS3, the BBSome ferries GPCRs across the transition zone, a diffusion barrier a
Externí odkaz:
https://doaj.org/article/e59a3eff2c394329b90389b66d19d2e9
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 3, p e1002933 (2013)
Post-translational modifications (PTMs) regulate protein activity, stability and interaction profiles and are critical for cellular functioning. Further regulation is gained through PTM interplay whereby modifications modulate the occurrence of other
Externí odkaz:
https://doaj.org/article/af07f9cd7f89409587665aa16f51eeef
Autor:
Christina S Moesslacher, Jonathan Woodsmith, Elisabeth Auernig, Andreas Feichtner, Evelyne Jany-Luig, Stefanie Jehle, Josephine M Worseck, Christian L Heine, Eduard Stefan, Ulrich Stelzl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::266d3e782731c48dab3fa116afc35454
https://doi.org/10.15252/rc.2023269367
https://doi.org/10.15252/rc.2023269367
Autor:
Christina S. Moesslacher, Jonathan Woodsmith, Elisabeth Auernig, Andreas Feichtner, Evelyne Jany-Luig, Stefanie Jehle, Josephine M. Worseck, Christian L. Heine, Eduard Stefan, Ulrich Stelzl
NF2 (Neurofibromine 2, merlin) is frequently inactivated in cancer, where its NF2 tumor suppressor functionality is tightly coupled to protein conformation. How NF2 conformation is regulated and how NF2 conformation influences tumor suppressor activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af409b006bfb78ec24da39043fee8777
https://doi.org/10.1101/2022.12.11.519953
https://doi.org/10.1101/2022.12.11.519953