Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jonathan Witztum"'
Publikováno v:
Neurobiology of Stress, Vol 24, Iss , Pp 100518- (2023)
Working memory is a process for actively maintaining and updating task-relevant information, despite interference from competing inputs, and is supported in part by sustained activity in prefrontal cortical pyramidal neurons and coordinated interacti
Externí odkaz:
https://doaj.org/article/f3a1d3f87c794f00be5bdc7757e9f23e
Autor:
Siobhan S. Pattwell, Conor Liston, Deqiang Jing, Ipe Ninan, Rui R. Yang, Jonathan Witztum, Mitchell H. Murdock, Iva Dincheva, Kevin G. Bath, B. J. Casey, Karl Deisseroth, Francis S. Lee
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Flexible fear-related responses may be advantageous in adolescence. Here the authors use microprisms to image prefrontal cortical spine maturation across development and report that plasticity in adolescent fear extinction responses is associated wit
Externí odkaz:
https://doaj.org/article/4d58c976b94049eb80787cf1cc8bf9b2
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90282 (2014)
The availability of many complete, annotated proteomes enables the systematic study of the relationships between protein conservation and functionality. We explore this question based solely on the presence or absence of protein homologues (a.k.a. co
Externí odkaz:
https://doaj.org/article/7b126516fb4c4aceb76919f9b15f9981
Autor:
Megan Allen, Ben S. Huang, Michael J. Notaras, Aiman Lodhi, Estibaliz Barrio-Alonso, Pablo J. Lituma, Paul Wolujewicz, Jonathan Witztum, Francesco Longo, Maoshan Chen, David W. Greening, Eric Klann, M. Elizabeth Ross, Conor Liston, Dilek Colak
Publikováno v:
Molecular Psychiatry. 27:2470-2484
The cellular mechanisms of autism spectrum disorder (ASD) are poorly understood. Cumulative evidence suggests that abnormal synapse function underlies many features of this disease. Astrocytes regulate several key neuronal processes, including the fo
Autor:
Megan, Allen, Ben S, Huang, Michael J, Notaras, Aiman, Lodhi, Estibaliz, Barrio-Alonso, Pablo J, Lituma, Paul, Wolujewicz, Jonathan, Witztum, Francesco, Longo, Maoshan, Chen, David W, Greening, Eric, Klann, M Elizabeth, Ross, Conor, Liston, Dilek, Colak
Publikováno v:
Molecular psychiatry. 27(5)
The cellular mechanisms of autism spectrum disorder (ASD) are poorly understood. Cumulative evidence suggests that abnormal synapse function underlies many features of this disease. Astrocytes regulate several key neuronal processes, including the fo
Autor:
Megan Allen, Ben S. Huang, Michael J. Notaras, Aiman Lodhi, Estibaliz Barrio-Alonso, Pablo J. Lituma, Paul Wolujewicz, Jonathan Witztum, Francesco Longo, Maoshan Chen, David W. Greening, Eric Klann, M. Elizabeth Ross, Conor Liston, Dilek Colak
Publikováno v:
Molecular Psychiatry. 27:2369-2369
Autor:
D. L. Rosenthal, Ben S. Huang, Thu N. Huynh, D. C. Shaver, Haruo Kasai, Katherine Lopez, Robert N. Fetcho, Y. Meng, R. N. Moda-Sava, Emily Alway, Teresa A. Milner, L. Nellissen, Puja K. Parekh, Conor Liston, Mitchell H. Murdock, Jonathan Witztum, Haruhiko Bito, Logan Grosenick, Karl Deisseroth
Publikováno v:
Science. 364
Why is ketamine an antidepressant? A better understanding of the mechanisms underlying the action of antidepressants is urgently needed. Moda-Sava et al. explored a possible mode of action for the drug ketamine, which has recently been shown to help
Autor:
Iva Dincheva, Karl Deisseroth, Deqiang Jing, Francis S. Lee, Kevin G. Bath, B. J. Casey, Siobhan S. Pattwell, Conor Liston, Mitchell H. Murdock, Jonathan Witztum, Ipe Ninan, Rui R. Yang
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Nature Communications
Nature Communications
Fear can be highly adaptive in promoting survival, yet it can also be detrimental when it persists long after a threat has passed. Flexibility of the fear response may be most advantageous during adolescence when animals are prone to explore novel, p
Hierarchical partitioning of metazoan protein conservation profiles provides new functional insights
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 3, p e90282 (2014)
PLoS ONE, Vol 9, Iss 3, p e90282 (2014)
The availability of many complete, annotated proteomes enables the systematic study of the relationships between protein conservation and functionality. We explore this question based solely on the presence or absence of protein homologues (a.k.a. co
Publikováno v:
Journal of Vision. 15:999