Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jonathan Warrel"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract For the COVID-19 pandemic, viral transmission has been documented in many historical and geographical contexts. Nevertheless, few studies have explicitly modeled the spatiotemporal flow based on genetic sequences, to develop mitigation strat
Externí odkaz:
https://doaj.org/article/0a68916765484e4a875126b56157bd78
Autor:
Laurens Manning, Moses Laman, Anna Rosanas-Urgell, Berwin Turlach, Susan Aipit, Cathy Bona, Jonathan Warrell, Peter Siba, Ivo Mueller, Timothy M E Davis
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48701 (2012)
BACKGROUND: Although rapid diagnostic tests (RDTs) have practical advantages over light microscopy (LM) and good sensitivity in severe falciparum malaria in Africa, their utility where severe non-falciparum malaria occurs is unknown. LM, RDTs and pol
Externí odkaz:
https://doaj.org/article/4c4d6d3cadf0490f8037e0d6e3a70f3b
Autor:
Moses Laman, Brioni R Moore, John M Benjamin, Gumul Yadi, Cathy Bona, Jonathan Warrel, Johanna H Kattenberg, Tamarah Koleala, Laurens Manning, Bernadine Kasian, Leanne J Robinson, Naomi Sambale, Lina Lorry, Stephan Karl, Wendy A Davis, Anna Rosanas-Urgell, Ivo Mueller, Peter M Siba, Inoni Betuela, Timothy M E Davis
Publikováno v:
PLoS Medicine, Vol 11, Iss 12, p e1001773 (2014)
BackgroundArtemisinin combination therapies (ACTs) with broad efficacy are needed where multiple Plasmodium species are transmitted, especially in children, who bear the brunt of infection in endemic areas. In Papua New Guinea (PNG), artemether-lumef
Externí odkaz:
https://doaj.org/article/ef696de515304ce4b62fb7e240ed75be
Autor:
Ivo Mueller, Timothy M. E. Davis, Louise Turner, Thor G. Theander, Janavi S. Rambhatla, James G. Beeson, Stephen J. Rogerson, Thomas Lavstsen, Jonathan Warrel, Laurens Manning, Moses Laman
Publikováno v:
The Journal of infectious diseases. 219(5)
BACKGROUND Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) mediates parasite sequestration in postcapillary venules in P. falciparum malaria. PfEMP1 types can be classified based on their cysteine-rich interdomain region (CIDR) domains.
Autor:
Arif Harmanci, Ekta Khurana, William Meyerson, Jonathan Warrel, Carl Herrmann, Xiaotong Li, Shantao Li, Leonidas Salichos, Sushant Kumar, Calvin Wing Yiu Chan, Patrick McGillivray, Yan Zhang, Alexander Martinez Fundichely, Mark Gerstein, Gad Getz, Morten Nielsen, Lucas Lochovsky
Publikováno v:
Cancer Research. 78:1279-1279
Cancer progression is an evolutionary process during which thousands of somatic variants are accumulated within an individual. In the classic view of cancer progression, a handful of driver variants are thought to give a positive selection advantage
Autor:
Jonathan Warrel, Johanna H Kattenberg, Tamarah Koleala, Timothy M. E. Davis, Brioni R. Moore, Wendy A. Davis, Naomi Sambale, Ivo Mueller, Stephan Karl, John Benjamin, Bernadine Kasian, Anna Rosanas-Urgell, Inoni Betuela, Gumul Yadi, Leanne J. Robinson, Moses Laman, Laurens Manning, Lina Lorry, Peter Siba, Cathy Bona
Publikováno v:
PLoS Medicine, Vol 11, Iss 12, p e1001773 (2014)
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS Medicine
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS Medicine
In a randomized controlled trial Tim Davis and colleagues investigate Artemisinin-naphthoquine versus artemether-lumefantrine for the treatment of P. falciparum and P. vivax malaria. Please see later in the article for the Editors' Summary
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Autor:
Ivo Mueller, Laurens Manning, Susan Aipit, Peter Siba, Timothy M. E. Davis, Moses Laman, Ilomo Hwaiwhange, Jonathan Warrel, Trevor Mare, John D Vince, Harin Karunajeewa
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 51(5)
Background. Although routine lumbar puncture (LP) is often recommended as part of the assessment of fever-associated seizures in children, accumulating evidence questions its value and reveals a decrease in its frequency. Our primary hypothesis was t
Autor:
Jing Zhang, Donghoon Lee, Vineet Dhiman, Peng Jiang, Jie Xu, Patrick McGillivray, Hongbo Yang, Jason Liu, William Meyerson, Declan Clarke, Mengting Gu, Shantao Li, Shaoke Lou, Jinrui Xu, Lucas Lochovsky, Matthew Ung, Lijia Ma, Shan Yu, Qin Cao, Arif Harmanci, Koon-Kiu Yan, Anurag Sethi, Gamze Gürsoy, Michael Rutenberg Schoenberg, Joel Rozowsky, Jonathan Warrell, Prashant Emani, Yucheng T. Yang, Timur Galeev, Xiangmeng Kong, Shuang Liu, Xiaotong Li, Jayanth Krishnan, Yanlin Feng, Juan Carlos Rivera-Mulia, Jessica Adrian, James R Broach, Michael Bolt, Jennifer Moran, Dominic Fitzgerald, Vishnu Dileep, Tingting Liu, Shenglin Mei, Takayo Sasaki, Claudia Trevilla-Garcia, Su Wang, Yanli Wang, Chongzhi Zang, Daifeng Wang, Robert J. Klein, Michael Snyder, David M. Gilbert, Kevin Yip, Chao Cheng, Feng Yue, X. Shirley Liu, Kevin P. White, Mark Gerstein
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
ENCODE is a resource comprising thousands of functional genomic datasets. Here, the authors present custom annotation within ENCODE for cancer, highlighting a workflow that can help prioritise key elements in oncogenesis.
Externí odkaz:
https://doaj.org/article/d3ef1766b33842a5aa6bd3194efeba4e
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
There are many methods to detect cancer-driving mutations. Here, the authors harness the variant allele frequency of mutations in tumor cells of a single individual to present a method that can estimate growth patterns and identify driver gene evolut
Externí odkaz:
https://doaj.org/article/6c6a5bf56eac4983a05e8f4f824a7d1c
Autor:
Timothy M. E. Davis, Ivo Mueller, Peter Siba, David W. Smith, Cathy Bona, Joanna Noronha, Inoni Betuela, Jonathan Warrel, Ilomo Hwaiwhanje, Laurens Manning, Susan Aipit, Moses Laman
Publikováno v:
BMC Infectious Diseases
Background Viral central nervous system (CNS) infections are common in countries where malaria is endemic but, due to limited laboratory facilities, few studies have systematically examined the prevalence and clinical consequences of the presence of