Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jonathan W. Tanner"'
Autor:
Clifford A. Schmiesing, Anthea F. Buchin, H. Rick Ortega, Joshua H. Atkins, Jonathan W. Tanner, David R. Drover, Alex Macario
Publikováno v:
Journal of Clinical Monitoring and Computing. 25:175-181
Monitoring depth of anesthesia via the processed electroencephalogram (EEG) has been found useful in reducing the amount of anesthetic drugs, optimizing wake-up times, and, in some studies, reducing awareness. Our goal was to determine if titrating s
Publikováno v:
Biochemistry. 40:5075-5080
Xenon and dichloromethane are inhalational anesthetic agents whose binding to myoglobin has been demonstrated by X-ray crystallography. We explore the thermodynamic significance of such binding using differential scanning calorimetry, circular dichro
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 42:436-441
Firefly luciferase is considered a reasonable model of in vivo anesthetic targets despite being destabilized by anesthetics, as reflected by differential scanning calorimetry (DSC). We examined the interaction between two inhaled anesthetics, ATP, lu
Publikováno v:
Toxicology Letters. :387-391
1. We have used differential scanning calorimetry to measure the halothane induced change in stability of five lipid-free proteins in aqueous solution. 2. The temperature at peak heat capacity (Tm) as the sample is heated provides a measure of stabil
Publikováno v:
Anesthesia and analgesia. 117(5)
Autor:
Ara A. Chalian, Lee A. Fleisher, Zhe Yan, Joseph S. Savino, Jonathan W. Tanner, David Lin, Renyu Liu
Publikováno v:
Survey of Anesthesiology. 57:313
Background Providing anesthesia and managing airways in the electrophysiology suite can be challenging because of its unique setting outside of the conventional operating room. We report our experience of several cases of reported airway trauma inclu
Publikováno v:
Molecular pharmacology. 56(2)
A loss of potency as one ascends a homologous series of compounds (cutoff effect) is often used to map the dimensions of binding sites on a protein target. The implicit assumption of steric hindrance is rarely confirmed with direct binding measuremen
Publikováno v:
Biochimica et biophysica acta. 1430(1)
Inhalational anesthetic agents are known to alter protein function, but the nature of the interactions underlying these effects remains poorly understood. We have used differential scanning calorimetry to study the effects of the anesthetic agent hal
Publikováno v:
Anesthesiology. 90(1)
Background Recent studies have demonstrated that volatile general anesthetic agents such as halothane and isoflurane may bind to discrete sites on protein targets. In the case of bovine serum albumin, the sites of halothane and chloroform binding hav
Autor:
David A. Katzka, Jeff E. Mandel, Gregory G. Ginsberg, David C. Metz, Michael L. Kochman, Jonathan W. Tanner, Gary R. Lichtenstein
Publikováno v:
American Journal of Gastroenterology. 101:S520-S521