Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jonathan W. Paul"'
Autor:
Christopher W. Rowe, Sam Faulkner, Jonathan W. Paul, Jorge M. Tolosa, Craig Gedye, Cino Bendinelli, Katie Wynne, Shaun McGrath, John Attia, Roger Smith, Hubert Hondermarck
Publikováno v:
BMC Endocrine Disorders, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Nerves and neurotrophic growth factors are emerging promoters of cancer growth. The precursor for Nerve Growth Factor (proNGF) is overexpressed in thyroid cancer, but its potential role as a clinical biomarker has not been reporte
Externí odkaz:
https://doaj.org/article/472217499a334f7eb9d616eb0fd394ef
Autor:
Tamas Zakar, Jonathan W. Paul
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The characteristics of fetal membrane cells and their phenotypic adaptations to support pregnancy or promote parturition are defined by global patterns of gene expression controlled by chromatin structure. Heritable epigenetic chromatin modifications
Externí odkaz:
https://doaj.org/article/3d0fb073eab2482ca725badf85d3f938
Publikováno v:
Symmetry, Vol 7, Iss 4, Pp 1981-1988 (2015)
We present a hypothesis for a mechanism involving self-organization of small functional units that leads to organ-level synchronization of uterine contractions in human labor. This view is in contrast to the long-held presumption that the synchronize
Externí odkaz:
https://doaj.org/article/93305da580014443a9fd7af4279dbdae
Publikováno v:
Reproductive Sciences. 30:203-220
The intracellular signaling pathways that regulate myometrial contractions can be targeted by drugs for tocolysis. The agents, 2-APB, glycyl-H-1152, and HC-067047, have been identified as inhibitors of uterine contractility and may have tocolytic pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4cebaa407e26d96e9e86d02eef3ca57
https://doi.org/10.1007/s43032-022-01000-2
https://doi.org/10.1007/s43032-022-01000-2
Autor:
Marina Paul, Tamas Zakar, Jason Phung, Amy Gregson, Anna Paredes Barreda, Trent A. Butler, Frederick R. Walker, Craig Pennell, Roger Smith, Jonathan W. Paul
Publikováno v:
Reproductive Sciences.
The mechanism by which human labor is initiated in the presence of elevated circulating progesterone levels remains unknown. Recent evidence indicates that the progesterone-metabolizing enzyme, 20α-hydroxysteroid dehydrogenase (20α-HSD), encoded by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::602e1e896121d3a8bccd366ce3e9f4ae
https://doi.org/10.1007/s43032-023-01183-2
https://doi.org/10.1007/s43032-023-01183-2
Publikováno v:
Reproductive Sciences. 29:3134-3146
The pregnant uterus remains relaxed throughout fetal gestation before transforming to a contractile phenotype at term to facilitate birth. Despite ongoing progress, the precise mechanisms that regulate this phenotypic transformation are not yet under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe5364451bfd4d0388a974f3e36a70b
https://doi.org/10.1007/s43032-021-00778-x
https://doi.org/10.1007/s43032-021-00778-x
Publikováno v:
Integrative Psychological and Behavioral Science. 56:180-205
A perennial challenge of evolutionary psychology is explaining prosocial traits such as a preference for fairness rather than inequality, compassion towards suffering, and an instinctive ability to coordinate within small teams. Considering recent fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a540910c6cc552e618d4e0c5e4d3a357
https://doi.org/10.1007/s12124-021-09606-y
https://doi.org/10.1007/s12124-021-09606-y
Autor:
Jason Phung, Carol Wang, Jocelyn Reeders, Tamas Zakar, Jonathan W. Paul, Sonika Tyagi, Craig E. Pennell, Roger Smith
Publikováno v:
American journal of obstetrics and gynecology.
The onset of preterm labor is associated with inflammation. Previous studies suggested that this is distinct from the inflammation observed during term labor. Our previous work on 44 genes differentially expressed in myometria in term labor demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3215bce4b8eb1188fd044528dddc511
https://pubmed.ncbi.nlm.nih.gov/36002050
https://pubmed.ncbi.nlm.nih.gov/36002050
Publikováno v:
Current Opinion in Physiology. 13:145-154
The mechanisms that bring about the onset of labor in humans remain poorly understood. Previous research has extensively explored signalling pathways that maintain myometrial relaxation and identified roles for key molecules, including cyclic nucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e581337984699b5436ff09160a757df6
https://doi.org/10.1016/j.cophys.2019.11.010
https://doi.org/10.1016/j.cophys.2019.11.010
Autor:
Roger Smith, Jonathan W. Paul, Michael B. Thompson, Trent Butler, Camilla M. Whittington, Jorge M. Tolosa, Joshua O Kemsley
Publikováno v:
Journal of Comparative Physiology B. 190:49-62
Nonapeptides and their receptors regulate a diverse range of physiological processes. We assessed the contractile responsiveness of uteri from the squamate viviparous-oviparous species pair, Pseudemoia entrecasteauxii and Lampropholis guichenoti, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7480bd2d0e77d984f090b35e0937b36
https://doi.org/10.1007/s00360-019-01254-4
https://doi.org/10.1007/s00360-019-01254-4