Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jonathan W. Lovelace"'
Autor:
Patricia S. Pirbhoy, Carrie R. Jonak, Rashid Syed, Donovan A. Argueta, Pedro A. Perez, Mark B. Wiley, Keon Hessamian, Jonathan W. Lovelace, Khaleel A. Razak, Nicholas V. DiPatrizio, Iryna M. Ethell, Devin K. Binder
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 13, Iss 1, Pp 1-19 (2021)
Abstract Background Individuals with Fragile X syndrome (FXS) and autism spectrum disorder (ASD) exhibit an array of symptoms, including sociability deficits, increased anxiety, hyperactivity, and sensory hyperexcitability. It is unclear how endocann
Externí odkaz:
https://doaj.org/article/01f84f04ae0b44e19a2193954cf12657
Autor:
Maham Rais, Jonathan W. Lovelace, Xinghao S. Shuai, Walker Woodard, Steven Bishay, Leo Estrada, Ashwin R. Sharma, Austin Nguy, Anna Kulinich, Patricia S. Pirbhoy, Arnold R. Palacios, David L. Nelson, Khaleel A. Razak, Iryna M. Ethell
Publikováno v:
Neurobiology of Disease, Vol 162, Iss , Pp 105577- (2022)
Background: Fragile X syndrome (FXS) is a leading genetic cause of autism and intellectual disability with cortical hyperexcitability and sensory hypersensitivity attributed to loss and hypofunction of inhibitory parvalbumin-expressing (PV) cells. Ou
Externí odkaz:
https://doaj.org/article/59d4773c4e2a47b0bd3f51d0b57d3dd3
Minocycline Treatment Reverses Sound Evoked EEG Abnormalities in a Mouse Model of Fragile X Syndrome
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Fragile X Syndrome (FXS) is a leading known genetic cause of intellectual disability. Many symptoms of FXS overlap with those in autism including repetitive behaviors, language delays, anxiety, social impairments and sensory processing deficits. Elec
Externí odkaz:
https://doaj.org/article/8d270ad9337949bcb61292f5f8fb02fc
Publikováno v:
Neurobiology of Disease, Vol 138, Iss , Pp 104794- (2020)
Fragile X Syndrome (FXS) is a leading known genetic cause of intellectual disability with symptoms that include increased anxiety and social and sensory processing deficits. Recent EEG studies in humans with FXS have identified neural oscillation def
Externí odkaz:
https://doaj.org/article/bbf1b4ed1a434892b1ca9a1472b5a2e7
Autor:
Anna O. Kulinich, Sarah M. Reinhard, Maham Rais, Jonathan W. Lovelace, Veronica Scott, Devin K. Binder, Khaleel A. Razak, Iryna M. Ethell
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
Background: Fragile X syndrome (FXS) is the most common genetic cause of autism and intellectual disability. Fragile X mental retardation gene (Fmr1) knock-out (KO) mice display core deficits of FXS, including abnormally increased sound-evoked respon
Externí odkaz:
https://doaj.org/article/108f5851c377418eb303a2016ddaffd0
Publikováno v:
Neurobiology of Disease, Vol 115, Iss , Pp 39-48 (2018)
Identification of comparable biomarkers in humans and validated animal models will facilitate pre-clinical to clinical therapeutic pipelines to treat neurodevelopmental disorders. Fragile X Syndrome (FXS) is a leading known genetic cause of intellect
Externí odkaz:
https://doaj.org/article/1cc18bd730804721b25fb4daed81274d
Autor:
Jonathan W. Lovelace, Teresa H. Wen, Sarah Reinhard, Mike S. Hsu, Harpreet Sidhu, Iryna M. Ethell, Devin K. Binder, Khaleel A. Razak
Publikováno v:
Neurobiology of Disease, Vol 89, Iss , Pp 126-135 (2016)
Sensory processing deficits are common in autism spectrum disorders, but the underlying mechanisms are unclear. Fragile X Syndrome (FXS) is a leading genetic cause of intellectual disability and autism. Electrophysiological responses in humans with F
Externí odkaz:
https://doaj.org/article/a81fff4772fd45278235d0617b513808
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 12 (2018)
Translational comparison of rodent models of neurological and neuropsychiatric diseases to human electroencephalography (EEG) biomarkers in these conditions will require multisite rodent EEG on the skull surface, rather than local area electrocortico
Externí odkaz:
https://doaj.org/article/ee95f88d301c4dbabf031d848eaf8cec
Publikováno v:
Neurobiology of Aging. 120:10-26
Neural oscillations at specific frequency bands are associated with cognitive functions and can identify abnormalities in cortical dynamics. In this study, we analyzed EEG signals recorded from auditory and frontal cortex of awake mice across young,
Autor:
Keon Hessamian, Carrie R. Jonak, Patricia S Pirbhoy, Jonathan W. Lovelace, Nicholas V. DiPatrizio, Khaleel A. Razak, Rashid Syed, Donovan A Argueta, Mark B Wiley, Iryna M. Ethell, Pedro A. Perez, Devin K. Binder
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 13, Iss 1, Pp 1-19 (2021)
Journal of neurodevelopmental disorders, vol 13, iss 1
Journal of Neurodevelopmental Disorders
Journal of neurodevelopmental disorders, vol 13, iss 1
Journal of Neurodevelopmental Disorders
Background Individuals with Fragile X syndrome (FXS) and autism spectrum disorder (ASD) exhibit an array of symptoms, including sociability deficits, increased anxiety, hyperactivity, and sensory hyperexcitability. It is unclear how endocannabinoid (