Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Jonathan W. Arthur"'
Autor:
Jonathan W. Arthur, Hilda A. Pickett, Pasquale M. Barbaro, Tatjana Kilo, Raja S. Vasireddy, Traude H. Beilharz, David R. Powell, Emma L. Hackett, Bruce Bennetts, Julie A. Curtin, Kristi Jones, John Christodoulou, Roger R. Reddel, Juliana Teo, Tracy M. Bryan
Publikováno v:
eJHaem, Vol 2, Iss 2, Pp 157-166 (2021)
Abstract Telomere biology disorders (TBDs), including dyskeratosis congenita (DC), are a group of rare inherited diseases characterized by very short telomeres. Mutations in the components of the enzyme telomerase can lead to insufficient telomere ma
Externí odkaz:
https://doaj.org/article/36c1fe6971a84a47afc842d5b03c9c42
Autor:
Matloob Khushi, Imraan M. Dean, Erdahl T. Teber, Megan Chircop, Jonathan W. Arthur, Neftali Flores-Rodriguez
Publikováno v:
BMC Bioinformatics, Vol 18, Iss S16, Pp 149-159 (2017)
Abstract Background Cell division (mitosis) results in the equal segregation of chromosomes between two daughter cells. The mitotic spindle plays a pivotal role in chromosome alignment and segregation during metaphase and anaphase. Structural or func
Externí odkaz:
https://doaj.org/article/6060a3a615214ba6a716a631795c3dcf
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Protein colocalisation is often studied using pixel intensity-based coefficients such as Pearson, Manders, Li or Costes. However, these methods cannot be used to study object-based colocalisations in biological systems. Therefore, a novel me
Externí odkaz:
https://doaj.org/article/2faddc290bb648358aa38548d73e9b1a
Autor:
Rebecca A. Dagg, Hilda A. Pickett, Axel A. Neumann, Christine E. Napier, Jeremy D. Henson, Erdahl T. Teber, Jonathan W. Arthur, C. Patrick Reynolds, Jayne Murray, Michelle Haber, Alexander P. Sobinoff, Loretta M.S. Lau, Roger R. Reddel
Publikováno v:
Cell Reports, Vol 19, Iss 12, Pp 2544-2556 (2017)
Summary: Acquisition of replicative immortality is currently regarded as essential for malignant transformation. This is achieved by activating a telomere lengthening mechanism (TLM), either telomerase or alternative lengthening of telomeres, to coun
Externí odkaz:
https://doaj.org/article/949142d7003c4a95bf12c9b1f0e62d36
Autor:
Samantha L. Ginn, Claus V. Hallwirth, Sophia H.Y. Liao, Erdahl T. Teber, Jonathan W. Arthur, Jianmin Wu, Hong Ching Lee, Szun S. Tay, Min Hu, Roger R. Reddel, Matthew P. McCormack, Adrian J. Thrasher, Marina Cavazzana, Stephen I. Alexander, Ian E. Alexander
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 6, Iss , Pp 1-14 (2017)
In early gene therapy trials for SCID-X1, using γ-retroviral vectors, T cell leukemias developed in a subset of patients secondary to insertional proto-oncogene activation. In contrast, we have reported development of T cell leukemias in SCID-X1 mic
Externí odkaz:
https://doaj.org/article/b02280667afa4fc3ad72ef3d4c6c6486
Autor:
Traude H. Beilharz, Roger R. Reddel, Tatjana Kilo, Kristi J. Jones, David R. Powell, Bruce Bennetts, Jonathan W. Arthur, Raja S. Vasireddy, Tracy M. Bryan, Julie Curtin, Pasquale M Barbaro, Hilda A. Pickett, John Christodoulou, Juliana Teo, Emma L. Hackett
Publikováno v:
eJHaem. 2:157-166
Autor:
Jonathan W, Arthur, Hilda A, Pickett, Pasquale M, Barbaro, Tatjana, Kilo, Raja S, Vasireddy, Traude H, Beilharz, David R, Powell, Emma L, Hackett, Bruce, Bennetts, Julie A, Curtin, Kristi, Jones, John, Christodoulou, Roger R, Reddel, Juliana, Teo, Tracy M, Bryan
Publikováno v:
EJHaem. 2(2)
Telomere biology disorders (TBDs), including dyskeratosis congenita (DC), are a group of rare inherited diseases characterized by very short telomeres. Mutations in the components of the enzyme telomerase can lead to insufficient telomere maintenance
Autor:
Pablo Fernandez-Penas, Jonathan W. Arthur, Marina Ali, Ali Azimi, Kimberley L. Kaufman, Steven Kossard
Publikováno v:
Journal of Dermatological Science. 91:69-78
Background The boundaries between actinic keratosis (AK), Bowen’s disease (BD), and cutaneous squamous cell carcinoma (cSCC) are sometimes not clear. Large-scale proteomic profiling studies of these lesions are also non-existent. Objective To evalu
Autor:
Erdahl Teber, Oliver Holmes, Nicholas K. Hayward, Katia Nones, Loretta Lau, Hilda A. Pickett, Jonathan W. Arthur, Nicola Waddell, Graham J. Mann, James S. Wilmott, Christine E. Napier, Michael Lee, Rebecca A. Dagg, Roger R. Reddel, Sean M. Grimmond, Joyce H. Y. Lee, Ann-Marie Patch, Richard A. Scolyer, Peter Johansson, John V. Pearson
Publikováno v:
Nucleic Acids Research
The replicative immortality of human cancer cells is achieved by activation of a telomere maintenance mechanism (TMM). To achieve this, cancer cells utilise either the enzyme telomerase, or the Alternative Lengthening of Telomeres (ALT) pathway. Thes
Autor:
Erdahl Teber, Hong Ching Lee, Jonathan W. Arthur, Sophia H.Y. Liao, Adrian J. Thrasher, Claus V. Hallwirth, Stephen I. Alexander, Roger R. Reddel, Szun S. Tay, Ian E. Alexander, Jianmin Wu, Matthew P. McCormack, Samantha L. Ginn, Marina Cavazzana, Min Hu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 6, Iss, Pp 1-14 (2017)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
In early gene therapy trials for SCID-X1, using γ-retroviral vectors, T cell leukemias developed in a subset of patients secondary to insertional proto-oncogene activation. In contrast, we have reported development of T cell leukemias in SCID-X1 mic