Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jonathan W Nelson"'
Autor:
Greg J. Duncan, Sam D. Ingram, Katie Emberley, Jo Hill, Christian Cordano, Ahmed Abdelhak, Michael McCane, Jennifer E. Jenks, Nora Jabassini, Kirtana Ananth, Skylar J. Ferrara, Brittany Stedelin, Benjamin Sivyer, Sue A. Aicher, Thomas S. Scanlan, Trent A. Watkins, Anusha Mishra, Jonathan W. Nelson, Ari J. Green, Ben Emery
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Chronic demyelination and oligodendrocyte loss deprive neurons of crucial support. It is the degeneration of neurons and their connections that drives progressive disability in demyelinating disease. However, whether chronic demyelination tr
Externí odkaz:
https://doaj.org/article/157dbf6e704c453ab56f2275e3086749
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0152742 (2016)
The epoxyeicosatrienoic acid (EET) neutralizing enzyme soluble epoxide hydrolase (sEH) is a neuronal enzyme, which has been localized in both the cytosol and peroxisomes. The molecular basis for its dual localization remains unclear as sEH contains a
Externí odkaz:
https://doaj.org/article/39113a645c4b423bae9e43079003efdc
Autor:
Alejandra Becerra Calderon, Urvi Nikhil Shroff, Sachin Deepak, Audrey Izuhara, Greta Trogen, Alicia A. McDonough, Susan B. Gurley, Jonathan W. Nelson, János Peti‐Peterdi, Georgina Gyarmati
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 10 (2024)
Background The vasoconstrictor effects of angiotensin II via type 1 angiotensin II receptors in vascular smooth muscle cells are well established, but the direct effects of angiotensin II on vascular endothelial cells (VECs) in vivo and the mechanism
Externí odkaz:
https://doaj.org/article/b22d9c46fc7f4fb09a92d8b207f080bd
Autor:
Catherine M. Davis, Thierno M. Bah, Wenri H. Zhang, Jonathan W. Nelson, Kirsti Golgotiu, Xiao Nie, Farah N. Alkayed, Jennifer M. Young, Randy L. Woltjer, Lisa C. Silbert, Marjorie R. Grafe, Nabil J. Alkayed
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 7, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction The pathogenesis of vascular cognitive impairment (VCI) is not fully understood. GPR39, an orphan G‐protein coupled receptor, is implicated in neurological disorders but its role in VCI is unknown. Methods We performed GPR39 i
Externí odkaz:
https://doaj.org/article/4d536f292a5248eaa224b392eaaa42b2
Autor:
Jonathan W. Nelson, David I. Ortiz-Melo, Natalie K. Mattocks, Jacqueline M. Emathinger, Jessica Prescott, Katherine Xu, Robert C. Griffiths, Rumie Wakasaki, Paul D. Piehowski, Michael P. Hutchens, Thomas M. Coffman, Susan B. Gurley
Publikováno v:
Kidney360
BACKGROUND: ACE2 is a key enzyme in the renin-angiotensin system (RAS) capable of balancing the RAS by metabolizing angiotensin II (AngII). First described in cardiac tissue, abundance of ACE2 is highest in the kidney, and it is also expressed in sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b439da9c86ad6af99a218de45a6160b6
https://doi.org/10.34067/kid.0001622022
https://doi.org/10.34067/kid.0001622022
Autor:
Vanderlene L. Kung, Jonathan W. Nelson
Publikováno v:
Kidney360. 4:578-579
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6af4e466547bcd5a55c8e9de643868b
https://doi.org/10.34067/kid.0000000000000111
https://doi.org/10.34067/kid.0000000000000111
Autor:
Alicia A. McDonough, Kenneth E. Bernstein, Susan B. Gurley, Zhidan Xiang, Jorge F. Giani, Jonathan W. Nelson, Joshua A. Robertson, Donna L. Ralph
Publikováno v:
Am J Physiol Renal Physiol
The renal nephron consists of a series of distinct cell types that function in concert to maintain fluid and electrolyte balance and blood pressure. The renin-angiotensin system (RAS) is central to Na(+) and volume balance. We aimed to determine how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f0c28ec2d5ddca71ad3a0db1fb5f26
https://doi.org/10.1152/ajprenal.00014.2021
https://doi.org/10.1152/ajprenal.00014.2021
Publikováno v:
Am J Physiol Renal Physiol
Cullin-RING ligases are a family of E3 ubiquitin ligases that control cellular processes through regulated degradation. Cullin 3 targets with-no-lysine kinase 4 (WNK4), a kinase that activates the Na(+)-Cl(−) cotransporter (NCC), the main pathway f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f055f35553dafda93bfc0317e8c24d6
https://europepmc.org/articles/PMC9236871/
https://europepmc.org/articles/PMC9236871/
Autor:
Nabil J. Alkayed, Zhiping Cao, Zu Yuan Qian, Shanthi Nagarajan, Xuehong Liu, Jonathan W. Nelson, Fuchun Xie, Bingbing Li, Wei Fan, Lijuan Liu, Marjorie R. Grafe, Catherine M. Davis, Xiangshu Xiao, Anthony P. Barnes, Sanjiv Kaul
Publikováno v:
Am J Physiol Cell Physiol
Arachidonic acid metabolites epoxyeicosatrienoates (EETs) and hydroxyeicosatetraenoates (HETEs) are important regulators of myocardial blood flow and coronary vascular resistance (CVR), but their mechanisms of action are not fully understood. We appl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d83b90989936980b9196f801431338
https://europepmc.org/articles/PMC9255704/
https://europepmc.org/articles/PMC9255704/
Autor:
Randy Woltjer, Chris Kizzar, Rupali S. Avasare, Naly Setthavongsack, Victoria Krajbich, Vy Nguyen, Kelly D. Smith, Nicole K. Andeen, Daphne Garcia, Susan B. Gurley, Jonathan W. Nelson, Phillip W. Raess, Bridget A. Robinson
Publikováno v:
Kidney International Reports
Kidney International Reports, Vol 5, Iss 3, Pp 368-372 (2020)
Kidney International Reports, Vol 5, Iss 3, Pp 368-372 (2020)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e074461c92a4c2d42deb9af3de5ef6c
http://europepmc.org/articles/PMC7056856
http://europepmc.org/articles/PMC7056856