Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jonathan W Armond"'
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 11, p e1004607 (2015)
Kinetochores are multi-protein complexes that mediate the physical coupling of sister chromatids to spindle microtubule bundles (called kinetochore (K)-fibres) from respective poles. These kinetochore-attached K-fibres generate pushing and pulling fo
Externí odkaz:
https://doaj.org/article/91035537a0d249fc8b9d51c36d375eab
Autor:
Francesco Paolo Casale, Giorgio Giurato, Giovanni Nassa, Jonathan W Armond, Chris J Oates, Davide Corá, Andrea Gamba, Sach Mukherjee, Alessandro Weisz, Mario Nicodemi
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88485 (2014)
Estrogen responsive breast cancer cell lines have been extensively studied to characterize transcriptional patterns in hormone-responsive tumors. Nevertheless, due to current technological limitations, genome-wide studies have typically been limited
Externí odkaz:
https://doaj.org/article/41f927f14c2b4216af613dacc620646e
Publikováno v:
Journal of cell science. 135(17)
Chromosomal instability (CIN), the process of increased chromosomal alterations, compromises genomic integrity and has profound consequences on human health. Yet, our understanding of the molecular and mechanistic basis of CIN initiation remains limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de21234c64ce024348abe8e2ffb52e95
https://pubmed.ncbi.nlm.nih.gov/35929456
https://pubmed.ncbi.nlm.nih.gov/35929456
Publikováno v:
Bioinformatics
Summary: During mitosis, chromosomes are attached to the mitotic spindle via large protein complexes called kinetochores. The motion of kinetochores throughout mitosis is intricate and automated quantitative tracking of their motion has already revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb01d8ea12f712c7c1db75bc3361a3e4
https://doi.org/10.1093/bioinformatics/btw087
https://doi.org/10.1093/bioinformatics/btw087
Autor:
Patrick Meraldi, Andrew D. McAinsh, Elina Vladimirou, Catarina P. Samora, Ivana Gasic, Jonathan W. Armond, Nunu Mchedlishvili
Publikováno v:
DEVELOPMENTAL CELL
Developmental Cell, Vol. 27, No 1 (2013) pp. 60-71
Developmental Cell, Vol. 27, No 1 (2013) pp. 60-71
SummaryKinetochores are the central force-generating machines that move chromosomes during cell division. It is generally assumed that kinetochores move in an autonomous manner. However, we reveal here that movements of neighboring sister-kinetochore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a85cf0b2338a5919cea05d334e1ba3
Autor:
Jonathan W. Armond, Sach Mukherjee, Anas A. Rana, Krishanu Saha, Mario Nicodemi, Rudolf Jaenisch, Chris J. Oates
Publikováno v:
Nature Publishing Group
Scientific Reports
Scientific Reports
Many biological processes, including differentiation, reprogramming, and disease transformations, involve transitions of cells through distinct states. Direct, unbiased investigation of cell states and their transitions is challenging due to several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca62e857ca032a714e67bf65ea5f5ad8
https://doi.org/10.1038/srep03692
https://doi.org/10.1038/srep03692
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 27(13)
The force required to form a nanoscale tube from a supported lipid bilayer (SLB) by pulling was measured using an atomic force microscope (AFM). The equilibrium membrane shape during an AFM pulling experiment was calculated and used to derive a gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1a4d88e664832e0bbb9f2f3234e346
https://pubmed.ncbi.nlm.nih.gov/21650171
https://pubmed.ncbi.nlm.nih.gov/21650171
Autor:
Jonathan W. Armond, Matthew S. Turner
Publikováno v:
Biophysical Journal. (8):1598-1607
The coupling between the depolymerization of microtubules (MTs) and the motion of the Dam1 ring complex is now thought to play an important role in the generation of forces during mitosis. Our current understanding of this motion is based on a number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0d60d5116250d31d0a254fa626386c