Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jonathan V. Dietz"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Mitochondrial cytochrome c oxidase is a heme aa3-copper oxygen reductase. Here, authors report that metal center-specific metallochaperones form dynamic assemblies to control heme a biosynthesis and coordinate copper transfer to the copper sites.
Externí odkaz:
https://doaj.org/article/43d49fed77534d76827f1f25f3c7eb73
Autor:
Jonathan V. Dietz, Mathilda M. Willoughby, Robert B. Piel, III, Teresa A. Ross, Iryna Bohovych, Hannah G. Addis, Jennifer L. Fox, William N. Lanzilotta, Harry A. Dailey, James A. Wohlschlegel, Amit R. Reddi, Amy E. Medlock, Oleh Khalimonchuk
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102125- (2021)
Heme is an essential cofactor required for a plethora of cellular processes in eukaryotes. In metazoans the heme biosynthetic pathway is typically partitioned between the cytosol and mitochondria, with the first and final steps taking place in the mi
Externí odkaz:
https://doaj.org/article/b5b8982ff5e84ce3a38023b6ecfea0bd
Publikováno v:
Cells, Vol 10, Iss 9, p 2198 (2021)
Cellular iron homeostasis and mitochondrial iron homeostasis are interdependent. Mitochondria must import iron to form iron–sulfur clusters and heme, and to incorporate these cofactors along with iron ions into mitochondrial proteins that support e
Externí odkaz:
https://doaj.org/article/b785e6f999f44efb903d5035a2d466cc
Publikováno v:
Cells
Cells, Vol 10, Iss 2198, p 2198 (2021)
Cells, Vol 10, Iss 2198, p 2198 (2021)
Cellular iron homeostasis and mitochondrial iron homeostasis are interdependent. Mitochondria must import iron to form iron–sulfur clusters and heme, and to incorporate these cofactors along with iron ions into mitochondrial proteins that support e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c400f2b99a95c622a6f85e286866fa7
https://pubmed.ncbi.nlm.nih.gov/34571846
https://pubmed.ncbi.nlm.nih.gov/34571846
Autor:
Mathilda M. Willoughby, Arushi Saini, Iryna Bohovych, Amit R. Reddi, Oleh Khalimonchuk, Jonathan V. Dietz, Amy E. Medlock, Osiris Martinez-Guzman
Publikováno v:
Journal of Cell Science.
Heme is a cofactor and signaling molecule that is essential for much of aerobic life. All heme-dependent processes in eukaryotes require that heme is trafficked from its site of synthesis in the mitochondria to hemoproteins located throughout the cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f04ea186cbbfa0af9457843f5fa9f131
https://doi.org/10.1242/jcs.237917
https://doi.org/10.1242/jcs.237917
Publikováno v:
Mitochondrion
Spatiotemporal changes in the abundance, shape, and cellular localization of the mitochondrial network, also known as mitochondrial dynamics, are now widely recognized to play a key role in mitochondrial and cellular physiology as well as disease sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c41e6b7ed51c280a188f91b0b6fe045
https://europepmc.org/articles/PMC6814530/
https://europepmc.org/articles/PMC6814530/
Autor:
Oleh Khalimonchuk, Osiris Martinez-Guzman, Jonathan V. Dietz, Iryna Bohovych, Amit R. Reddi, Amy E. Medlock
Heme is an essential cofactor and signaling molecule. All heme-dependent processes require that heme is trafficked from its site of synthesis in the mitochondria to hemoproteins in virtually every subcellular compartment. However, the mechanisms gove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9106d438499c95b8f45b913d14773393
Publikováno v:
Free Radical Biology and Medicine. 112:142-143
Well-maintained mitochondrial functioning is crucial for cellular physiology. Thus, multiple mechanisms are in place to preserve mitochondrial welfare upon homeostatic challenges. One such mechanism - known as protein quality control (PQC) - comprise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77dfc16ce0445784f9b9869e002584b0
https://doi.org/10.1016/j.freeradbiomed.2017.10.215
https://doi.org/10.1016/j.freeradbiomed.2017.10.215
Autor:
Osiris Martinez-Guzman, Oleh Khalimonchuk, Amit R. Reddi, Amy E. Medlock, Iryna Bohovych, Jonathan V. Dietz
Publikováno v:
Free Radical Biology and Medicine. 128:S51
Heme is an essential cofactor involved in a plethora of vital functions. Heme is required to be in most subcellular compartments, but the way, in which it is transported from the mitochondria - its site of synthesis - to those compartments is poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c5d411f12c2585de04f846957984df2
https://doi.org/10.1016/j.freeradbiomed.2018.10.088
https://doi.org/10.1016/j.freeradbiomed.2018.10.088