The Antiviral Potential of AdipoRon, an Adiponectin Receptor Agonist, Reveals the Ability of Zika Virus to Deregulate Adiponectin Receptor Expression

Autor: Daed El Safadi, Grégorie Lebeau, Jonathan Turpin, Christian Lefebvre d’Hellencourt, Nicolas Diotel, Wildriss Viranaicken, Pascale Krejbich-Trotot

Publikováno v: Viruses, Vol 16, Iss 1, p 24 (2023)

Zika virus (ZIKV) is a pathogenic member of the flavivirus family, with several unique characteristics. Unlike any other arbovirus, ZIKV can be transmitted sexually and maternally, and thus produce congenital syndromes (CZS) due to its neurotropism.

Externí odkaz: https://doaj.org/article/4d38b04deab24ae8b134af996c21850a

The epidemic of Dengue virus type-2 Cosmopolitan genotype on Reunion Island relates to its active circulation in the Southwestern Indian Ocean neighboring islands

Autor: Hervé Pascalis, Jonathan Turpin, Marjolaine Roche, Pascale Krejbich, Gilles Gadea, Célestine Atyame Nten, Philippe Desprès, Patrick Mavingui

Publikováno v: Heliyon, Vol 5, Iss 4, Pp e01455- (2019)

Reunion Island is currently experiencing an epidemic caused by Dengue virus type-2 (DENV-2) resulting in over 6,763 cases from austral summer 2017 to winter 2018. Phylogenetic analyses on two non-imported cases of dengue infection from Reunion Island

Externí odkaz: https://doaj.org/article/31e3b1cf9e76443985c693be6283fa0b

The ZIKA Virus Delays Cell Death Through the Anti-Apoptotic Bcl-2 Family Proteins

Autor: Jonathan Turpin, Etienne Frumence, Philippe Desprès, Wildriss Viranaicken, Pascale Krejbich-Trotot

Publikováno v: Cells, Vol 8, Iss 11, p 1338 (2019)

Zika virus (ZIKV) is an emerging human mosquito-transmitted pathogen of global concern, known to be associated with complications such as congenital defects and neurological disorders in adults. ZIKV infection is associated with induction of cell dea

Externí odkaz: https://doaj.org/article/cd8192b83838423194e6b4b357c6aa44

ZIKA Virus Envelope Protein Forms Disulfide Bond-Dependent Polymers: Evidence for A Redox Imbalance during Infection

Autor: Grégorie Lebeau, Jonathan Turpin, Etienne Frumence, Daed El Safadi, Wissal harrabi, Philippe Desprès, Pascale Krejbich-Trotot, wildriss viranaïcken

Flaviviruses replicate in membrane factories associated with the endoplasmic reticulum (ER). Significant levels of flavivirus viral protein accumulation contribute to ER stress. As a consequence, the host cell exhibits an Unfolded Protein Response (U

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd93949e7cfa4e74312eb7feae6c6d7
https://doi.org/10.20944/preprints202204.0030.v1

CHOP Pro-Apoptotic Transcriptional Program in Response to ER Stress Is Hacked by Zika Virus

Autor: Grégorie Lebeau, Wildriss Viranaicken, Jonathan Turpin, Pascale Krejbich-Trotot, Daed El-Safadi, Philippe Desprès, Etienne Frumence

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2021, 22, pp.3750. ⟨10.3390/ijms22073750⟩
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3750, p 3750 (2021)

International audience; Zika virus (ZIKV) is an emerging mosquito-borne flavivirus considered as a threat to human health due to large epidemics and serious clinical outcomes such as microcephaly in new-borns. Like all flaviviruses, ZIKV relies on th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17856bdb8e56140fd1a547114fbd9897
http://europepmc.org/articles/PMC8038490