Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jonathan T. Sutton"'
Autor:
James Hodovan, O’Neil R. Mason, Brian P. Davidson, Jeffry E. Powers, Paul S. Sheeran, Matthew A. Muller, Jonathan T. Sutton, Jonathan R. Lindner
Publikováno v:
JACC Cardiovasc Imaging
Objectives The authors investigated ideal acoustic conditions on a clinical scanner custom-programmed for ultrasound (US) cavitation-mediated flow augmentation in preclinical models. We then applied these conditions in a first-in-human study to test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35936c3b28c84b9801c08d8665351145
https://europepmc.org/articles/PMC7018586/
https://europepmc.org/articles/PMC7018586/
Autor:
Kevin J. Haworth, J. K. Griffin, Shiva Kumar Shanmukhappa, D. M. Patton, Melvin E. Klegerman, Christy K. Holland, Jonathan T. Sutton, Melanie R. Moody, David D. McPherson
Publikováno v:
Drug Delivery. 23:3594-3605
Ultrasound is both a valuable diagnostic tool and a promoter of beneficial tissue bioeffects for the treatment of cardiovascular disease. Vascular effects can be mediated by mechanical oscillations of circulating microbubbles that may also encapsulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565f8ddf488481342fcbc9bea396efe1
https://doi.org/10.1080/10717544.2016.1212441
https://doi.org/10.1080/10717544.2016.1212441
Autor:
Eric L. Miller, Jonathan T. Sutton, Phillip Alexander, Yongzhi Zhang, Chanikarn Power, Tao Sun, Muna Aryal, Nathan McDannold, Natalia Vykhodtseva
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Cavitation-facilitated microbubble-mediated focused ultrasound therapy is a promising method of drug delivery across the blood-brain barrier (BBB) for treating many neurological disorders. Unlike ultrasound thermal therapies, during which magnetic re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8038c5a2d438500e9f3e45bab24ae38
https://doi.org/10.1073/pnas.1713328114
https://doi.org/10.1073/pnas.1713328114
Autor:
Deborah Vela, Christy K. Holland, Nikolas M. Ivancevich, Jonathan T. Sutton, Stephen R. Perrin
Publikováno v:
Ultrasound in Medicine & Biology. 39:813-824
We investigated ultrasound-enhanced thrombolysis in two whole-blood clot models using a Food and Drug Administration-approved contrast agent (Definity, Lantheus Medical Imaging; Billerica, MA USA) and thrombolytic drug (recombinant tissue-type plasmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cdbed1289f8cd58babfae81337e7499
https://doi.org/10.1016/j.ultrasmedbio.2012.12.008
https://doi.org/10.1016/j.ultrasmedbio.2012.12.008
Autor:
Can Baris Top, Margaret S. Livingstone, Jonathan T. Sutton, Nick Todd, Nathan McDannold, Natalia Vykhodtseva
This study investigated thermal ablation and skull-induced heating with a 230 kHz transcranial MRI-guided focused ultrasound (TcMRgFUS) system in nonhuman primates. We evaluated real-time acoustic feedback and aimed to understand whether cavitation c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dad2283bf3af8700633a17f48abe13f
https://aperta.ulakbim.gov.tr/record/53759
https://aperta.ulakbim.gov.tr/record/53759
Autor:
Deborah Vela, Jonathan T. Sutton, Kathryn E. Hitchcock, Kevin J. Haworth, Danielle N. Caudell Stamper, Nikolas M. Ivancevich, Gail J. Pyne-Geithman, Christy K. Holland
Publikováno v:
Ultrasound in Medicine & Biology. 37:1240-1251
Ultrasound is known to enhance recombinant tissue plasminogen activator (rt-PA) thrombolysis. In this study, occlusive porcine whole blood clots were placed in flowing plasma within living porcine carotid arteries. Ultrasonically induced stable cavit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5121ff6a958377286f97e68db97b4d9
https://doi.org/10.1016/j.ultrasmedbio.2011.05.011
https://doi.org/10.1016/j.ultrasmedbio.2011.05.011
Autor:
Todd Abruzzo, Jonathan T. Sutton, Christy K. Holland, David D. McPherson, Melvin E. Klegerman, Kathryn E. Hitchcock, Deborah Vela, Gail J. Pyne-Geithman, Danielle N. Caudell, Yong-Jian Geng, Peppar E P Cyr
Publikováno v:
Journal of Controlled Release. 144:288-295
The goal of this study was to determine whether targeted, Rhodamine-labeled echogenic liposomes (Rh-ELIP) containing nanobubbles could be delivered to the arterial wall, and whether 1-MHz continuous wave ultrasound would enhance this delivery profile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8760b936fa005745ecad3be6776882cc
https://doi.org/10.1016/j.jconrel.2010.02.030
https://doi.org/10.1016/j.jconrel.2010.02.030
Autor:
Nathan McDannold, Chanikarn Power, Jonathan T. Sutton, Yongzhi Zhang, Tao Sun, Eric L. Miller
Publikováno v:
Applied Physics Letters. 111:163701
Sub-megahertz transmission is not usually adopted in pre-clinical small animal experiments for focused ultrasound (FUS) brain therapy due to the large focal size. However, low frequency FUS is vital for preclinical evaluations due to the frequency-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce1e6837322089ff9e369045d3bb4667
https://doi.org/10.1063/1.5000896
https://doi.org/10.1063/1.5000896
Publikováno v:
International Journal of Nanomedicine
JT Sutton,1 JL Raymond,1 MC Verleye,2 GJ Pyne-Geithman,3 CK Holland4 1University of Cincinnati, Biomedical Engineering Program, Cincinnati,OH, 2University of Notre Dame Department of Chemical Engineering, Notre Dame, IN, 3University of Cincinnati, Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2adccacfff86e6a600c35c8d3015a3d1
https://www.dovepress.com/pulsed-ultrasound-enhances-the-delivery-of-nitric-oxide-from-bubble-li-peer-reviewed-article-IJN
https://www.dovepress.com/pulsed-ultrasound-enhances-the-delivery-of-nitric-oxide-from-bubble-li-peer-reviewed-article-IJN
Publikováno v:
Expert opinion on drug delivery. 10(5)
Ultrasound (US) has been developed as both a valuable diagnostic tool and a potent promoter of beneficial tissue bioeffects for the treatment of cardiovascular disease. These effects can be mediated by mechanical oscillations of circulating microbubb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020baff5bc0fb77031c8c01e86dc4cbd
https://pubmed.ncbi.nlm.nih.gov/23448121
https://pubmed.ncbi.nlm.nih.gov/23448121