Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jonathan T Haselman"'
Autor:
Christine M. Custer, Paul M. Dummer, Matthew A. Etterson, Jonathan T. Haselman, Sandra Schultz, Natalie Karouna-Renier, Cole Matson
Publikováno v:
Toxics, Vol 12, Iss 9, p 660 (2024)
Tree swallow nest boxes were deployed at sites proximal to two putative aqueous film forming foam (AFFF) sources in the Duluth, MN area, as well as along the St. Louis River and a reference lake for comparative purposes in 2019, 2020 and 2021. The tw
Externí odkaz:
https://doaj.org/article/956ce884de69404bb50f68347f06c651
Autor:
Jonathan T Haselman, Jennifer H Olker, Patricia A Kosian, Joseph J Korte, Jeffrey S Denny, Joseph E Tietge, Michael W Hornung, Sigmund J Degitz
Publikováno v:
Toxicol Sci
Iodothyronine deiodinases (DIO) are key enzymes that influence tissue-specific thyroid hormone levels during thyroid-mediated amphibian metamorphosis. Within the larger context of evaluating chemicals for thyroid system disrupting potential, chemical
Autor:
Jonathan T. Haselman, John W. Nichols, Kali Z. Mattingly, Michael W. Hornung, Sigmund J. Degitz
Publikováno v:
Mathematical Biosciences. :109021
Autor:
Joseph J. Korte, Jeffrey S. Denny, Jennifer H Olker, Joseph A. Swintek, Patricia A. Kosian, Joseph E. Tietge, John W. Nichols, Sigmund J. Degitz, Jonathan T. Haselman, Michael W. Hornung
Publikováno v:
Toxicol Sci
Chemical safety evaluation is in the midst of a transition from traditional whole-animal toxicity testing to molecular pathway-based in vitro assays and in silico modeling. However, to facilitate the shift in reliance on apical effects for risk asses
Autor:
Jennifer H. Olker, Joseph J. Korte, Jonathan T. Haselman, Michael W. Hornung, Sigmund J. Degitz
Publikováno v:
Aquatic toxicology (Amsterdam, Netherlands). 249
The transition to include in vitro-based data in chemical hazard assessment has resulted in the development and implementation of screening assays to cover a diversity of biological pathways, including recently added assays to interrogate chemical di
Autor:
Sigmund J. Degitz, Jennifer H Olker, Phillip C. Hartig, Mary C. Cardon, Jonathan T. Haselman, Joseph J. Korte, Jeffrey S. Denny, Michael W. Hornung
Publikováno v:
Toxicol In Vitro
The iodide recycling enzyme, iodotyrosine deiodinase (IYD), is a largely unstudied molecular mechanism through which environmental chemicals can potentially cause thyroid disruption. This highly conserved enzyme plays an essential role in maintaining
Autor:
Joseph J. Korte, Jonathan T. Haselman, Patricia A. Kosian, Sigmund J. Degitz, Allen W. Olmstead
Publikováno v:
Aquatic Toxicology. 199:240-251
The Larval Amphibian Growth and Development Assay (LAGDA) is an internationally harmonized testing guideline for evaluating effects of chronic chemical exposure in amphibians. In order to evaluate the effects of chronic exposure to an antiandrogenic
Autor:
Steven O. Simmons, Sigmund J. Degitz, Joseph E. Tietge, Susan C. Laws, Jonathan T. Haselman, Kevin M. Crofton, Michael W. Hornung, Tammy E. Stoker, Pamela D. Noyes, Patience Browne, Katie Paul Friedman, Mary E. Gilbert, Stan Barone
Publikováno v:
Environmental Health Perspectives
Background: Extensive clinical and experimental research documents the potential for chemical disruption of thyroid hormone (TH) signaling through multiple molecular targets. Perturbation of TH signaling can lead to abnormal brain development, cognit
Autor:
Joseph J. Korte, Sigmund J. Degitz, Rodney D. Johnson, Yasushi Goto, Naoko Watanabe, Yu Onoda, Patricia A. Kosian, Yuta Onishi, Maki Sakurai, Taisen Iguchi, Jonathan T. Haselman, Yuki Ito
Publikováno v:
Journal of Applied Toxicology. 36:1651-1661
The Larval Amphibian Growth and Development Assay (LAGDA) is a globally harmonized chemical testing guideline developed by the U.S. Environmental Protection Agency in collaboration with Japan's Ministry of Environment to support risk assessment. The
Autor:
Patricia A. Kosian, Sigmund J. Degitz, Rodney D. Johnson, Jonathan T. Haselman, Taisen Iguchi, Joseph J. Korte, Allen W. Olmstead
Publikováno v:
Journal of Applied Toxicology. 36:1639-1650
The Larval Amphibian Growth and Development Assay (LAGDA) is a globally harmonized test guideline developed by the U.S. Environmental Protection Agency in collaboration with Japan's Ministry of the Environment. The LAGDA was designed to evaluate apic