Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jonathan Stefanowski"'
Autor:
René Riedel, Richard Addo, Marta Ferreira-Gomes, Gitta Anne Heinz, Frederik Heinrich, Jannis Kummer, Victor Greiff, Daniel Schulz, Cora Klaeden, Rebecca Cornelis, Ulrike Menzel, Stefan Kröger, Ulrik Stervbo, Ralf Köhler, Claudia Haftmann, Silvia Kühnel, Katrin Lehmann, Patrick Maschmeyer, Mairi McGrath, Sandra Naundorf, Stefanie Hahne, Özen Sercan-Alp, Francesco Siracusa, Jonathan Stefanowski, Melanie Weber, Kerstin Westendorf, Jakob Zimmermann, Anja E. Hauser, Sai T. Reddy, Pawel Durek, Hyun-Dong Chang, Mir-Farzin Mashreghi, Andreas Radbruch
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Memory B cells are important for protecting the host from pathogen rechallenge, but their properties and locations remain ill-defined. Here the authors show, using single-cell transcriptomics and repertoire analyses, that mouse spleen and bone marrow
Externí odkaz:
https://doaj.org/article/d1c99a7f8c7f4d7ab186f53fdfc1db4e
Autor:
Jonathan Stefanowski, Annemarie Lang, Ariana Rauch, Linus Aulich, Markus Köhler, Alexander F. Fiedler, Frank Buttgereit, Katharina Schmidt-Bleek, Georg N. Duda, Timo Gaber, Raluca A. Niesner, Anja E. Hauser
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Macrophages are essential players in the process of fracture healing, acting by remodeling of the extracellular matrix and enabling vascularization. Whilst activated macrophages of M1-like phenotype are present in the initial pro-inflammatory phase o
Externí odkaz:
https://doaj.org/article/778f8005d396428fa4d6a882223e736b
Autor:
David Reismann, Jonathan Stefanowski, Robert Günther, Asylkhan Rakhymzhan, Romano Matthys, Reto Nützi, Sandra Zehentmeier, Katharina Schmidt-Bleek, Georg Petkau, Hyun-Dong Chang, Sandra Naundorf, York Winter, Fritz Melchers, Georg Duda, Anja E. Hauser, Raluca A. Niesner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Longitudinal imaging of bone marrow would shed insight into long-term cellular dynamics within this compartment. Here, the authors develop a multi-photon imaging approach for the mouse femur and reveal extensive vascular plasticity within the bone ma
Externí odkaz:
https://doaj.org/article/5461e2efd91248698ccbbea37bccb7fc
Autor:
Jonathan Stefanowski, Romano Matthys, Martin Tschaikner, Ralf H. Adams, Markus Köhler, Robert Günther, Wjatscheslaw Liublin, Raluca A. Niesner, Alexander Ferdinand Fiedler, Reto Nützi, Georg N. Duda, Ariana Rauch, Maria Gabriele Bixel, David Reismann, Anja E. Hauser
Publikováno v:
Cytometry Part A. 97:483-495
Bone healing involves the interplay of immune cells, mesenchymal cells, and vasculature over the time course of regeneration. Approaches to quantify the spatiotemporal aspects of bone healing at cellular resolution during long bone healing do not yet
Autor:
Anja E. Hauser, Georg N. Duda, Paula Hoff, Jonathan Stefanowski, Annemarie Lang, Max Löhning, Alexandra Damerau, Shabnam Hemmati-Sadeghi, Angelique Wolter, Timo Gaber, Frank Buttgereit, Moritz Pfeiffenberger, Rainer Haag, Katharina Schmidt-Bleek
Publikováno v:
Bone. 154
The initial phase of fracture healing is crucial for the success of bone regeneration and is characterized by an inflammatory milieu and low oxygen tension (hypoxia). Negative interference with or prolongation of this fine-tuned initiation phase will
Autor:
Katharina Schmidt-Bleek, A. Kuppe, Rainer Haag, Georg N. Duda, Annemarie Lang, M. Loehning, Moritz Pfeiffenberger, Vikram Sunkara, Angelique Wolter, Timo Gaber, Anja E. Hauser, S. Helfmeier, Alexandra Damerau, Shabnam Hemmati-Sadeghi, Carsten Perka, Jochen Ringe, Jonathan Stefanowski, Frank Buttgereit, Paula Hoff
The initial phase of fracture healing decides on success of bone regeneration and is characterized by an inflammatory milieu and low oxygen tension (hypoxia). Negative interference with or prolongation of this fine-tuned initiation phase will ultimat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b2e8187d7943294744fbc714b368bf9
https://doi.org/10.1101/2020.07.02.182832
https://doi.org/10.1101/2020.07.02.182832
Autor:
Stefanie Hahne, Katrin Lehmann, Claudia Haftmann, Jannis Kummer, Melanie Weber, Silvia Kühnel, Daniel Schulz, Stefan Kröger, Ralf Köhler, Richard K. Addo, Jakob Zimmermann, Ulrike Menzel, Frederik Heinrich, Andreas Radbruch, Patrick Maschmeyer, Rebecca Cornelis, Anja E. Hauser, Sai T. Reddy, Francesco Siracusa, Gitta Anne Heinz, Ulrik Stervbo, Özen Sercan-Alp, Mir-Farzin Mashreghi, Jonathan Stefanowski, Pawel Durek, René Riedel, Hyun-Dong Chang, Victor Greiff, Marta Ferreira-Gomes, Cora Klaeden, Mairi McGrath, Kerstin Westendorf, Sandra Naundorf
Publikováno v:
Nature Communications
Riedel, René; Addo, Richard; Ferreira-Gomes, Marta; Heinz, Gitta Anne; Heinrich, Frederik; Kummer, Jannis; Greiff, Victor; Schulz, Daniel; Klaeden, Cora; Cornelis, Rebecca; Menzel, Ulrike; Kröger, Stefan; Stervbo, Ulrik; Köhler, Ralf; Haftmann, Claudia; Kühnel, Silvia; Lehmann, Katrin; Maschmeyer, Patrick; McGrath, Mairi; Naundorf, Sandra; ... (2020). Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow. Nature Communications, 11(1), p. 2570. Springer Nature 10.1038/s41467-020-16464-6
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 11 (1)
bioRxiv
Riedel, René; Addo, Richard; Ferreira-Gomes, Marta; Heinz, Gitta Anne; Heinrich, Frederik; Kummer, Jannis; Greiff, Victor; Schulz, Daniel; Klaeden, Cora; Cornelis, Rebecca; Menzel, Ulrike; Kröger, Stefan; Stervbo, Ulrik; Köhler, Ralf; Haftmann, Claudia; Kühnel, Silvia; Lehmann, Katrin; Maschmeyer, Patrick; McGrath, Mairi; Naundorf, Sandra; ... (2020). Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow. Nature Communications, 11(1), p. 2570. Springer Nature 10.1038/s41467-020-16464-6
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 11 (1)
bioRxiv
At present, it is not clear how memory B lymphocytes are maintained over time, and whether only as circulating cells or also residing in particular tissues. Here we describe distinct populations of isotype-switched memory B lymphocytes (Bsm) of murin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1ec09bf63ee32a01767615ebc3627d
http://edoc.rki.de/176904/6894
http://edoc.rki.de/176904/6894
Autor:
Timo Gaber, Annemarie Lang, Anja E. Hauser, Alexandra Damerau, Marie-Christin Weber, Marieluise Kirchner, Moritz Pfeiffenberger, Katharina Schmidt-Bleek, Mattea Durst, Frank Buttgereit, Georg N. Duda, Jonathan Stefanowski, Paula Hoff
Publikováno v:
Acta biomaterialia. 86
Although several biomaterials for bone regeneration have been developed in the last decades, clinical application of bone morphogenetic protein 2 is clinically only approved when applied on an absorbable bovine collagen I scaffold (ACS) (Helistat; AC
Autor:
Sandra Zehentmeier, York Winter, Romano Matthys, Jonathan Stefanowski, Raluca Niesner, Asylkhan Rakhymzhan, Georg Petkau, Anja E. Hauser, Hyun-Dong Chang, Reto Nützi, David Reismann, Robert Günther, Georg N. Duda, Katharina Schmidt-Bleek, Fritz Melchers, Sandra Naundorf
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Nature Communications
The bone marrow is a central organ of the immune system, which hosts complex interactions of bone and immune compartments critical for hematopoiesis, immunological memory, and bone regeneration. Although these processes take place over months, most e
Autor:
Thomas Haaf, Daniel Erny, Laura Herrtwich, Dirk Wagner, Torsten Goldmann, Marie Follo, Dietmar Pfeifer, Christoph Hölscher, Reinhard E. Voll, Dominic Grün, Sachin D. Deshmukh, Thomas Ness, Marco Prinz, Teodora Nikolova, Bernhard Kremer, Vassilis G. Gorgoulis, Konstantinos Evangelou, Anja E. Hauser, Indrajit Nanda, Jonathan Stefanowski, Claudius Klein, Christine Dierks, Michael H. Sieweke, Antigoni Triantafyllopoulou, Manfred Fliegauf, Leif Rogell, Tom Aschman, Andreas Diefenbach, Sandrine Sarrazin, Sagar, Andrés J. López-Contreras, Nikolas Münke, Julia Senges, Mario M. Zaiss, Philipp Henneke, Veronika Horn, Maximilian Seidl, Kourosh Gharun
Publikováno v:
Cell
Granulomas are immune cell aggregates formed in response to persistent inflammatory stimuli. Granuloma macrophage subsets are diverse and carry varying copy numbers of their genomic information. The molecular programs that control the differentiation