Zobrazeno 1 - 2
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pro vyhledávání: '"Jonathan Semidey-Hurtado"'
Autor:
Katherine Stanford, Vrushank Davé, Deepal Patel, Jamaal Hardee, Zhi Tian, Diane Allen-Gipson, Jaymin J. Kathiriya, Jonathan Semidey-Hurtado, Prerna Malaney, Emily Palumbo
PTEN phosphorylation at its C-terminal (C-tail) serine/threonine cluster negatively regulates its tumor suppressor function. However, the consequence of such inhibition and its downstream effects in driving lung cancer remain unexplored. Herein, we a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9367846f79a7c066c698511bccc7a7d2
https://europepmc.org/articles/PMC6103743/
https://europepmc.org/articles/PMC6103743/
Autor:
Jonathan Semidey-Hurtado, Jamaal Hardee, Prerna Malaney, Zhi Tian, Daniel Hennessey, Deepal Patel, Kate Stanford, Vrushank Davé, Diane Allen-Gipson, Emily Palumbo
Publikováno v:
Cancer Research. 76:3682-3682
Loss of function of tumor suppressor PTEN (Phosphatase and tensin homolog) causes cancer in various tissues. PTEN C-terminal phosphorylation (pPTEN) inactivates PTEN, leading to multiple malignancies with increased severity. However, little is known