Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jonathan Schmid-Burgk"'
Autor:
Jonathan Strecker, Sara Jones, Balwina Koopal, Jonathan Schmid-Burgk, Bernd Zetsche, Linyi Gao, Kira S. Makarova, Eugene V. Koonin, Feng Zhang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
The Cas12b family of CRISPR nucleases has been underutilized in mammalian cells due to the high temperature requirement of known members. Here the authors engineer BhCas12b to overcome this limitation for robust and specific genome editing applicatio
Externí odkaz:
https://doaj.org/article/e6ea12311957487294bb0381d2fecb20
Autor:
Jianzhong Zhu, Yugeng Zhang, Rolando Cuevas, Adriana Forero, Jayeeta Dhar, Mikkel Ibsen, Jonathan Schmid-Burgk, Tobias Schmidt, Madhavi Ganapathiraju, Takashi Fujita, Rune Hartmann, Zhijian Chen, Sailen Barik, Veit Hornung, Carolyn Coyne, Saumendra Sarkar
Publikováno v:
The Journal of Immunology. 192:122.18-122.18
Virus infection is sensed in the cytoplasm by RIG-I, which requires RNA and poly-ubiquitin binding to induce type I interferon (IFN), and activate cellular innate immunity. We show that unlike mouse, the human IFN-inducible oligoadenylate synthetases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f20b81dfcf94255a09db52e6e1749fa5
https://doi.org/10.4049/jimmunol.192.supp.122.18
https://doi.org/10.4049/jimmunol.192.supp.122.18