Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jonathan Sabio-Ortiz"'
Autor:
Gabriele Stephan, Sara Haddock, Shuai Wang, Hediye Erdjument-Bromage, Wenke Liu, Niklas Ravn-Boess, Joshua D. Frenster, Devin Bready, Julia Cai, Rebecca Ronnen, Jonathan Sabio-Ortiz, David Fenyo, Thomas A. Neubert, Dimitris G. Placantonakis
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114229- (2024)
Summary: GPR133 (ADGRD1) is an adhesion G-protein-coupled receptor that signals through Gαs/cyclic AMP (cAMP) and is required for the growth of glioblastoma (GBM), an aggressive brain malignancy. The regulation of GPR133 signaling is incompletely un
Externí odkaz:
https://doaj.org/article/22cad31820a94f3da72fef14f8760c05
Autor:
Niklas Ravn-Boess, Nainita Roy, Takamitsu Hattori, Devin Bready, Hayley Donaldson, Christopher Lawson, Cathryn Lapierre, Aryeh Korman, Tori Rodrick, Enze Liu, Joshua D. Frenster, Gabriele Stephan, Jordan Wilcox, Alexis D. Corrado, Julia Cai, Rebecca Ronnen, Shuai Wang, Sara Haddock, Jonathan Sabio Ortiz, Orin Mishkit, Alireza Khodadadi-Jamayran, Aris Tsirigos, David Fenyö, David Zagzag, Julia Drube, Carsten Hoffmann, Fabiana Perna, Drew R. Jones, Richard Possemato, Akiko Koide, Shohei Koide, Christopher Y. Park, Dimitris G. Placantonakis
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113374- (2023)
Summary: Glioblastoma (GBM) is the most common and aggressive primary brain malignancy. Adhesion G protein-coupled receptors (aGPCRs) have attracted interest for their potential as treatment targets. Here, we show that CD97 (ADGRE5) is the most promi
Externí odkaz:
https://doaj.org/article/e954f101e34e4454841a124bf6a6e405