Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Jonathan S.T. Sham"'
Autor:
Daniel T.T. Chua, Dan Xie, Ning-Fang Ma, Wings T.Y. Loo, Jiong Bi, Min Yue Zhang, Jackie M.W. Fung, Li Fu, Jonathan S.T. Sham, Betty H Y Chow, Louis W.C. Chow, Xin Yuan Guan
Publikováno v:
PROTEOMICS - Clinical Applications. 3:654-662
Adjuvant chemotherapy alongside radiotherapy is one of the effective therapies in nasopharyngeal carcinoma (NPC) treatment. However, the appearance of drug resistance is a major obstacle for anti-cancer chemotherapy and often causes failure of the ch
Autor:
Gordon K.H. Au, Jonathan S.T. Sham, Maria P. Wong, William I. Wei, John M. Nicholls, Daniel T.T. Chua
Publikováno v:
Head & Neck. 30:863-867
Background This single-center, phase II study assessed the safety/tolerability and initial efficacy of gefitinib in patients with nasopharyngeal carcinoma (NPC) pretreated with platinum-based chemotherapy. Methods Patients with recurrent and metastat
Autor:
Gavin P. Robertson, Carmen Chak-Lui Wong, Nathalie Wong, Evan Wai Lok Law, Maria Li Lung, Jonathan S.T. Sham, Ka Fu Cheong, Eric J. Stanbridge, Cathy Carfield Lo, Yue Cheng, King Chi Chan, Arthur Kwok Leung Cheung, Daniel Chua, Sai Wah Tsao, Fung Mei Kwong, Hong Lok Lung
Publikováno v:
International Journal of Cancer. 122:1288-1296
In previous studies, we successfully refined nasopharyngeal carcinoma (NPC) critical regions (CRs) mapping to chromosome 11q13 and 11q22-23. The chromosome 11 fragment containing the 1.8 Mb NPC CR at 11q13 (CR1), the CR at 11q22.3 mapped near D11S200
Autor:
Yuanhong Gao, Feng Yan Li, Zhi Fan Zeng, Jonathan S.T. Sham, Mei Ling Deng, Daniel T.T. Chua, Chong Zhao, Shao Xiong Wu, Han Yu Wang, Yong Bao
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 69:761-769
Local recurrence remains one of the major causes of failure in nasopharyngeal carcinoma (NPC). Stereotactic radiosurgery and fractionated stereotactic radiation therapy (FSRT) have recently evolved as a salvage option of NPC. This study was conducted
Autor:
Igor Kuzmin, Jonathan S.T. Sham, King Chi Chan, Dan Xie, Paulisally Hau Yi Lo, Daniel Chua, Fang Ping Xu, Michael I. Lerman, Maria Li Lung, Simon Law
Publikováno v:
Cancer Letters. 257:199-205
Reduced expression or loss of tumor suppressor genes play a key role in many cancers. In this study, we investigated the role of RASSF1A in the pathogenesis of esophageal squamous cell carcinoma (ESCC) and nasopharyngeal carcinoma (NPC). We detected
Publikováno v:
Cancer Letters. 252:36-42
Recently, we established a hepatocellular carcinoma (HCC) cell line (named H4-M) from a metastatic HCC tumor. In H4-M, a marker chromosome containing a homogeneously staining region (hsr) was identified by cytogenetic analysis. The hsr was characteri
Autor:
Gordon K.H. Au, Peter W. H. Lee, Anne S. McMillan, Jonathan S.T. Sham, Dora L.W. Kwong, Edmond H.N. Pow, Tracy T. C. Kwan
Publikováno v:
Cancer. 109:1344-1354
BACKGROUND. Radiotherapy (RT) promises optimistic results in the treatment of nasopharyngeal cancer (NPC). The objective of the current study was to map out prospectively the impact of NPC and RT on patients from diagnosis to 1 year posttreatment. ME
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 66:1415-1421
Background: Stereotactic radiosurgery has been employed as a salvage treatment of local failures of nasopharyngeal carcinoma (NPC). To identify patients that would benefit from radiosurgery, we reviewed our data with emphasis on factors that predicte
Autor:
Jonathan S.T. Sham, Dora L.W. Kwong, Mun-Hon Ng, Daniel T.T. Chua, Kai-Yuan Cao, Ying Zheng, Bo-Jian Zheng, Sze Park Ng, Liwei Lu
Publikováno v:
Cancer Science. 97:912-919
NK cells and alphabeta- and gammadelta-CTL play important roles in cellular immunity against tumors. We previously demonstrated that NPC patients have a quantitative and qualitative deficit in gammadelta-CTL and EBV-specific alphabeta-CTL when compar
Autor:
Shirley L. Xu, Jonathan S.T. Sham, Rick Chappell, Xiu Fang Liu, Ellie S.Y. Pang, To-Wai Leung, Stewart Y. Tung, Wing Hong Kwan, Tai Xiang Lu, Eng Huat Tan, Lillian L. Siu, Terence Tan, Yiu Tong Fu, Daniel T.T. Chua, Wai Hon Lau, Wai Man Sze, Anne W.M. Lee, Anthony T.C. Chan, Brian O'Sullivan, Paddy T M Chan
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 66:142-151
To compare the benefit achieved by concurrent chemoradiotherapy (CRT) and/or accelerated fractionation (AF) vs. radiotherapy (RT) alone with conventional fractionation (CF) for patients with T3-4N0-1M0 nasopharyngeal carcinoma (NPC).All patients were