Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Jonathan S. Serody"'
Autor:
Sonia J. Laurie, Joseph P. Foster, Danny W. Bruce, Hemamalini Bommiasamy, Oleg V. Kolupaev, Mostafa Yazdimamaghani, Samantha G. Pattenden, Nelson J. Chao, Stefanie Sarantopoulos, Joel S. Parker, Ian J. Davis, Jonathan S. Serody
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Type II innate lymphoid cells (ILC2s) maintain homeostasis and barrier integrity in mucosal tissues. In both mice and humans, ILC2s poorly reconstitute after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Determining the mec
Externí odkaz:
https://doaj.org/article/deafa590173041a485a51c32ab3e3f46
Autor:
Wolfgang Beckabir, Mi Zhou, Jin Seok Lee, Steven P. Vensko, Mark G. Woodcock, Hsing-Hui Wang, Sara E. Wobker, Gatphan Atassi, Alec D. Wilkinson, Kenneth Fowler, Leah M. Flick, Jeffrey S. Damrauer, Michael R. Harrison, Karen P. McKinnon, Tracy L. Rose, Matthew I. Milowsky, Jonathan S. Serody, William Y. Kim, Benjamin G. Vincent
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Neoadjuvant cisplatin-based chemotherapy is standard of care for muscle-invasive bladder cancer (MIBC). Immune checkpoint inhibition (ICI) alone, and ICI in combination with chemotherapy, have demonstrated promising pathologic response (
Externí odkaz:
https://doaj.org/article/20a284baf2454780aedd68c631ea83b7
Autor:
Hsuan Su, Kazuhiro Imai, Wei Jia, Zhiguo Li, Rachel A. DiCioccio, Jonathan S. Serody, Jonathan C. Poe, Benny J. Chen, Phuong L. Doan, Stefanie Sarantopoulos
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
De novo immune responses to myeloid and other blood-borne tumors are notably limited and ineffective, making our ability to promote immune responses with vaccines a major challenge. While focus has been largely on cytotoxic cell-mediated tumor eradic
Externí odkaz:
https://doaj.org/article/e5191fc99d69408f89ec5efebfa81933
Autor:
Ranganatha R. Somasagara, Xiaoyan Huang, Chunyu Xu, Jamil Haider, Jonathan S. Serody, Paul M. Armistead, TinChung Leung
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Personalized medicine holds tremendous promise for improving safety and efficacy of drug therapies by optimizing treatment regimens. Rapidly developed patient-derived xenografts (pdx) could be a helpful tool for analyzing the effect of drugs
Externí odkaz:
https://doaj.org/article/ca05924fb6f54487b4ff2e4948c6d8d3
Chemotherapy and Stem Cell Transplantation Increase p16INK4a Expression, a Biomarker of T-cell Aging
Autor:
William A. Wood, Janakiraman Krishnamurthy, Natalia Mitin, Chad Torrice, Joel S. Parker, Anna C. Snavely, Thomas C. Shea, Jonathan S. Serody, Norman E. Sharpless
Publikováno v:
EBioMedicine, Vol 11, Iss C, Pp 227-238 (2016)
The expression of markers of cellular senescence increases exponentially in multiple tissues with aging. Age-related physiological changes may contribute to adverse outcomes in cancer survivors. To investigate the impact of high dose chemotherapy and
Externí odkaz:
https://doaj.org/article/412c6a5db9574822929292e8cad3a443
Autor:
Jing Zhu, Tejendra Patel, Jordan A. Miller, Chad D. Torrice, Mehak Aggarwal, Margaret R. Sketch, Maurice D. Alexander, Paul M. Armistead, James M. Coghill, Tatjana Grgic, Katarzyna J. Jamieson, Jonathan R. Ptachcinski, Marcie L. Riches, Jonathan S. Serody, John L. Schmitz, J. Ryan Shaw, Thomas C. Shea, Oscar Suzuki, Benjamin G. Vincent, William A. Wood, Kamakshi V. Rao, Tim Wiltshire, Eric T. Weimer, Daniel J. Crona
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 858 (2020)
Tacrolimus exhibits high inter-patient pharmacokinetics (PK) variability, as well as a narrow therapeutic index, and therefore requires therapeutic drug monitoring. Germline mutations in cytochrome P450 isoforms 4 and 5 genes (CYP3A4/5) and the ATP-b
Externí odkaz:
https://doaj.org/article/3c55e94674f84324902c0900d35780ff
Autor:
Benjamin G. Vincent, Danielle M. File, Karen P. McKinnon, Dominic T. Moore, Jeffrey A. Frelinger, Edward J. Collins, Joseph G. Ibrahim, Lisa Bixby, Shannon Reisdorf, Sonia J. Laurie, Yara A. Park, Carey K. Anders, Frances A. Collichio, Hyman B. Muss, Lisa A. Carey, Hendrik W. van Deventer, E. Claire Dees, Jonathan S. Serody
Publikováno v:
J Immunol
Previous work from our group and others has shown that patients with breast cancer can generate a T cell response against specific human epidermal growth factor 2 (HER2) epitopes. In addition, preclinical work has shown that this T cell response can
Autor:
Benjamin G. Vincent, Jonathan S. Serody, Barbara Savoldo, Joel S. Parker, Sara R. Selitsky, Lisa M. Bixby, Jason Garness, Kevin Field, Elisa Landoni, Samuel J. Lee, Amber R. Washington, Shengjie Chai, Christof C. Smith
Supplemental Data File
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df27d3056d30beca5fd660ccccf851d
https://doi.org/10.1158/2326-6066.22542117
https://doi.org/10.1158/2326-6066.22542117
Autor:
Ivana Gojo, Jonathan S. Serody, Leo Luznik, Nathan D. Montgomery, Mark J. Levis, B. Douglas Smith, Amy E. DeZern, Gabrielle T. Prince, Jonathan A. Webster, Hendrik Van Deventer, Katarzyna Jamieson, Catherine C. Coombs, Matthew C. Foster, Hanna A. Knaus, Francesco Mazziotta, Rupkatha Mukhopadhyay, Alec D. Wilkinson, Karen P. McKinnon, Dominic Moore, Anastasia Ivanova, Benjamin G. Vincent, Joshua F. Zeidner
Supplemental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574ae48df49e97c2a4bc9c7170265627
https://doi.org/10.1158/2643-3230.22543396.v1
https://doi.org/10.1158/2643-3230.22543396.v1
Autor:
Benjamin G. Vincent, Jonathan S. Serody, Barbara Savoldo, Joel S. Parker, Sara R. Selitsky, Lisa M. Bixby, Jason Garness, Kevin Field, Elisa Landoni, Samuel J. Lee, Amber R. Washington, Shengjie Chai, Christof C. Smith
Current tumor neoantigen calling algorithms primarily rely on epitope/major histocompatibility complex (MHC) binding affinity predictions to rank and select for potential epitope targets. These algorithms do not predict for epitope immunogenicity usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ea07adc06de419a0a15c70f4ddd4a9
https://doi.org/10.1158/2326-6066.c.6549804
https://doi.org/10.1158/2326-6066.c.6549804