Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jonathan S. Peters"'
Autor:
Adrian L. Oblak, Zackary A. Cope, Sara K. Quinney, Ravi S. Pandey, Carla Biesdorf, Andi R. Masters, Kristen D. Onos, Leslie Haynes, Kelly J. Keezer, Jill A. Meyer, Jonathan S. Peters, Scott A. Persohn, Amanda A. Bedwell, Kierra Eldridge, Rachael Speedy, Gabriela Little, Sean‐Paul Williams, Brenda Noarbe, Andre Obenaus, Michael Sasner, Gareth R. Howell, Gregory W. Carter, Harriet Williams, Bruce T. Lamb, Paul R. Territo, Stacey J. Sukoff Rizzo
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Alzheimer's disease (AD) is the most common form of dementia. Beta‐secretase (BACE) inhibitors have been proposed as potential therapeutic interventions; however, initiating treatment once disease has significantly progressed
Externí odkaz:
https://doaj.org/article/049b9fdfe3964b8f8a93c11191a73a7d
Autor:
Paul R. Territo, Qi Huang Zheng, Jill A. Meyer, Hamideh Zarrinmayeh, Mingzhang Gao, Jonathan S. Peters, Barbara E. Glick-Wilson, Min Wang, Gary D. Hutchins, Mark A. Green
Publikováno v:
Applied Radiation and Isotopes. 144:10-18
The overexpression of P2X7R is associated with neuroinflammation and plays an important role in various neurodegenerative diseases. The [18F]fluoropropyl derivative of GSK1482160, [18F]IUR-1602, has been first prepared and examined as a new potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98cff1ccbebe0580480d22290f7af46b
https://doi.org/10.1016/j.apradiso.2018.11.006
https://doi.org/10.1016/j.apradiso.2018.11.006
Pharmacokinetic, pharmacodynamic and transcriptomic analyses of verubecestat treatment in 5XFAD mice
Autor:
Andrea R. Masters, Amanda A. Bedwell, Paul R. Territo, Jill A. Meyer, Kierra Eldridge, Bruce T. Lamb, Kristen D. Onos, Kelly J. Keezer, Jonathan S. Peters, Zackery A. Cope, Leslie Haynes, Lucas Figueiredo, Michael Sasner, Gregory W. Carter, Stacey J. Sukoff Rizzo, Gareth R. Howell, Carla Biesdorf, Sara K. Quinney, Scott C. Persohn, Rachael Speedy, Adrian L. Oblak
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e0bff3b383dc54cc7fe6bb8301a692c
https://doi.org/10.1002/alz.041491
https://doi.org/10.1002/alz.041491
Autor:
Min Wang, Hamideh Zarrinmayeh, Jonathan S. Peters, Gary D. Hutchins, Mark A. Green, Mingzhang Gao, Paul R. Territo, Qi Huang Zheng, Jill A. Meyer, Barbara E. Glick-Wilson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:1603-1609
The reference standard IUR-1601 ((S)-N-(2-chloro-3-(trifluoromethyl)benzyl)-1-(2-fluoroethyl)-5-oxopyrrolidine-2-carboxamide) was synthesized from tert-butyl (S)-5-oxopyrrolidine-2-carboxylate, fluoroethylbromide, and 2-chloro-3-(trifluoromethyl)benz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a84824cb602f534277dd8198a12ea5a
https://doi.org/10.1016/j.bmcl.2018.03.044
https://doi.org/10.1016/j.bmcl.2018.03.044
Autor:
Mingzhang Gao, Qi Huang Zheng, Jill A. Meyer, Gary D. Hutchins, Jonathan S. Peters, Hamideh Zarrinmayeh, Paul R. Territo, Min Wang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:2727-2730
The reference standard methyl (2-amino-5-(benzylthio)thiazolo[4,5-d]pyrimidin-7-yl)-d-leucinate (5) and its precursor 2-amino-5-(benzylthio)thiazolo[4,5-d]pyrimidin-7-yl)-d-leucine (6) were synthesized from 6-amino-2-mercaptopyrimidin-4-ol and BnBr w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ea5aef1f44e55eef748ddae7977e32e
https://doi.org/10.1016/j.bmcl.2017.04.052
https://doi.org/10.1016/j.bmcl.2017.04.052
Autor:
Paul R. Territo, Amanda A. Riley, Mark A. Green, Jonathan S. Peters, Min Wang, Mingzhang Gao, Brian P. McCarthy, Gary D. Hutchins, Qi Huang Zheng, Jill A. Meyer
Publikováno v:
Journal of Nuclear Medicine. 58:458-465
The purinergic receptor subtype 7 (P2X7R) represents a novel molecular target for imaging neuroinflammation via PET. GSK1482160, a potent P2X7R antagonist, has high receptor affinity, high blood-brain barrier penetration, and the ability to be radiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97423a0528b38589897b75054bf40848
https://doi.org/10.2967/jnumed.116.181354
https://doi.org/10.2967/jnumed.116.181354
Autor:
Mingzhang, Gao, Min, Wang, Barbara E, Glick-Wilson, Jill A, Meyer, Jonathan S, Peters, Paul R, Territo, Mark A, Green, Gary D, Hutchins, Hamideh, Zarrinmayeh, Qi-Huang, Zheng
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 144
The overexpression of P2X7R is associated with neuroinflammation and plays an important role in various neurodegenerative diseases. The [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2833c28796d8e708593fe2a4d68b835
https://pubmed.ncbi.nlm.nih.gov/30476885
https://pubmed.ncbi.nlm.nih.gov/30476885
Autor:
Jill A. Meyer, Amanda A. Riley, Kelly J. Keezer, Paul R. Territo, Michael Sasner, Brian P. McCarthy, Sara K. Quinney, Harriett Williams, Gareth R. Howell, Jonathan S. Peters, Bruce T. Lamb, Kristen D. Onos, David R. Jones, Stacey J. Sukoff Rizzo, Andrea R. Masters, Ingrid F. Metzger, Scott C. Persohn, Adrian L. Oblak
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ad8f2557235a45b3c6ffaf850cd151c
https://doi.org/10.1016/j.jalz.2018.06.729
https://doi.org/10.1016/j.jalz.2018.06.729
Autor:
Mingzhang, Gao, Min, Wang, Barbara E, Glick-Wilson, Jill A, Meyer, Jonathan S, Peters, Paul R, Territo, Mark A, Green, Gary D, Hutchins, Hamideh, Zarrinmayeh, Qi-Huang, Zheng
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(9)
The reference standard IUR-1601 ((S)-N-(2-chloro-3-(trifluoromethyl)benzyl)-1-(2-fluoroethyl)-5-oxopyrrolidine-2-carboxamide) was synthesized from tert-butyl (S)-5-oxopyrrolidine-2-carboxylate, fluoroethylbromide, and 2-chloro-3-(trifluoromethyl)benz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f355d85b2210d8157523ded9009cfcf
https://pubmed.ncbi.nlm.nih.gov/29628324
https://pubmed.ncbi.nlm.nih.gov/29628324
Autor:
Scott C. Persohn, Kierra Eldridge, Stacey J. Sukoff Rizzo, Jonathan S. Peters, Carla Biesdorf, Gareth R. Howell, Paul R. Territo, Harriet M. Williams, Leslie Haynes, Jill A. Meyer, Rachael Speedy, Sara K. Quinney, Adrian L. Oblak, Michael Sasner, Kelly J. Keezer, Amanda A. Bedwell, Bruce T. Lamb, Kristen D. Onos
Publikováno v:
Alzheimer's & Dementia. 15:P1304-P1305
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c427d7f7ca70b36a1e5065c3f2a4509
https://doi.org/10.1016/j.jalz.2019.06.3739
https://doi.org/10.1016/j.jalz.2019.06.3739