Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jonathan S. Kurche"'
Autor:
Rachel Z. Blumhagen, Jonathan S. Kurche, Carlyne D. Cool, Avram D. Walts, David Heinz, Tasha E. Fingerlin, Ivana V. Yang, David A. Schwartz
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a heterogeneous disease that is pathologically characterized by areas of normal-appearing lung parenchyma, active fibrosis (transition zones including fibroblastic foci) and dense fibrosis. D
Externí odkaz:
https://doaj.org/article/01706a12d28340c886415da719d291ac
Publikováno v:
Cells, Vol 11, Iss 20, p 3319 (2022)
Idiopathic pulmonary fibrosis (IPF) is a progressive disease of older adults characterized by fibrotic replacement of functional gas exchange units in the lung. The strongest risk factor for IPF is a genetic variantin the promoter region of the gel-f
Externí odkaz:
https://doaj.org/article/c3ec233daabe4d669eb83a41eaac1275
Autor:
Fabienne Gally, Sarah K. Sasse, Jonathan S. Kurche, Margaret A. Gruca, Jonathan H. Cardwell, Tsukasa Okamoto, Hong W. Chu, Xiaomeng Hou, Olivier B. Poirion, Justin Buchanan, Sebastian Preissl, Bing Ren, Sean P. Colgan, Robin D. Dowell, Ivana V. Yang, David A. Schwartz, Anthony N. Gerber
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
The G/T transversion rs35705950, located approximately 3 kb upstream of the MUC5B start site, is the cardinal risk factor for idiopathic pulmonary fibrosis (IPF). Here, we investigate the function and chromatin structure of this –3 kb region and pr
Externí odkaz:
https://doaj.org/article/b83bf4c5e2db4e1eaeaab26d621e57b0
Autor:
Evgenia Dobrinskikh, Corinne E. Hennessy, Jonathan S. Kurche, Eunjoo Kim, Alani M. Estrella, Jonathan Cardwell, Ivana V. Yang, David A. Schwartz
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 68:62-74
Autor:
Ian T. Stancil, Jacob E. Michalski, Corinne E. Hennessy, Kristina L. Hatakka, Ivana V. Yang, Jonathan S. Kurche, Mercedes Rincon, David A. Schwartz
Publikováno v:
Sci Transl Med
Chronic disease results from the failure of tissues to maintain homeostasis. In the lung, coordinated repair of the epithelium is essential for preserving homeostasis. In animal models and human lung disease, airway epithelial cells mobilize in respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da2f6e5d8daa8074812a2a63d7ba836
https://europepmc.org/articles/PMC9981332/
https://europepmc.org/articles/PMC9981332/
Publikováno v:
Translational Research
While the coronavirus disease 19 (COVID-19) pandemic has transformed the medical and scientific communites since it was first reported in late 2019, we are only beginning to understand the chronic health burdens associated with this disease. Although
Autor:
Naoko Hara, Corinne E. Hennessy, Evgenia Dobrinskikh, Alani Estrella, Jonathan S. Kurche, Ivana V. Yang, Marvin I. Schwarz, David A. Schwartz
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Idiopathic pulmonary fibrosis (IPF) is an incurable genetic disease that affects 5 million people worldwide. The gain-of-function MUC5B promoter variant rs35705950 is the dominant genetic risk factor for IPF, yet has a low penetrance. This raises the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fff4a74bde9ebd283e34dc97fde37f5
https://europepmc.org/articles/PMC8410112/
https://europepmc.org/articles/PMC8410112/
Autor:
Tsukasa Okamoto, Fabienne Gally, Anthony N. Gerber, Bing Ren, Jonathan S. Kurche, Sebastian Preissl, Xiaomeng Hou, Hong W. Chu, Olivier Poirion, David A. Schwartz, Jonathan Cardwell, Sarah K. Sasse, Justin Buchanan, Margaret Gruca, Ivana V. Yang, Robin D. Dowell, Sean P. Colgan
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
JCI Insight
JCI Insight
The G/T transversion rs35705950, located approximately 3 kb upstream of the MUC5B start site, is the cardinal risk factor for idiopathic pulmonary fibrosis (IPF). Here, we investigate the function and chromatin structure of this –3 kb region and pr
Publikováno v:
Thorax. 77(6)
BackgroundInterstitial lung disease (ILD) and pulmonary sarcoidosis are common respiratory diseases with a heterogeneous distribution worldwide. The global burden and temporal trends of ILD and sarcoidosis are rarely explored.MethodsUsing the classif
Autor:
Kevin K. Brown, Jonathan S. Kurche, Paul J. Wolters, Mauricio Rojas, Carlyne D. Cool, Avram D Walts, Jonathan A. Kropski, Iain R. Konigsberg, Tami J. Bang, Joyce S. Lee, David A. Schwartz, Jonathan Cardwell, Marvin I. Schwarz, Tsukasa Okamoto, Haruhiko Furusawa, Ivana V. Yang
Publikováno v:
Am J Respir Crit Care Med
American journal of respiratory and critical care medicine, vol 202, iss 10
American Journal of Respiratory and Critical Care Medicine
American journal of respiratory and critical care medicine, vol 202, iss 10
American Journal of Respiratory and Critical Care Medicine
Rationale: Chronic hypersensitivity pneumonitis (CHP) is caused by an immune response to antigen inhalation and is characterized by variable histopathological and clinical features. A subset of subjects with CHP have usual interstitial pneumonia and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434bad1eed8cd8f9f98cdaff7a93fe94
https://europepmc.org/articles/PMC7667907/
https://europepmc.org/articles/PMC7667907/