Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Jonathan S. Katz"'
Autor:
Jonathan S. Katz, Jeffrey D. Rothstein, Merit E. Cudkowicz, Angela Genge, Björn Oskarsson, Avis B. Hains, Chen Chen, Joshua Galanter, Braydon L. Burgess, William Cho, Geoffrey A. Kerchner, Felix L. Yeh, Arundhati Sengupta Ghosh, Sravanthi Cheeti, Logan Brooks, Lee Honigberg, Jessica A. Couch, Michael E. Rothenberg, Flavia Brunstein, Khema R. Sharma, Leonard van denBerg, James D. Berry, Jonathan D. Glass
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 1, Pp 50-66 (2022)
Abstract Objective Dual leucine zipper kinase (DLK), which regulates the c‐Jun N‐terminal kinase pathway involved in axon degeneration and apoptosis following neuronal injury, is a potential therapeutic target in amyotrophic lateral sclerosis (AL
Externí odkaz:
https://doaj.org/article/fe4980573fc74660b0489437b3effc6d
Autor:
Merit E. Cudkowicz, Stacy R. Lindborg, Namita A. Goyal, Robert G. Miller, Matthew J. Burford, James D. Berry, Katharine A. Nicholson, Tahseen Mozaffar, Jonathan S. Katz, Liberty J. Jenkins, Robert H. Baloh, Richard A. Lewis, Nathan P. Staff, Margaret A. Owegi, Donald A. Berry, Yael Gothelf, Yossef S. Levy, Revital Aricha, Ralph Z. Kern, Anthony J. Windebank, Robert H. Brown
Publikováno v:
Muscle & Nerve. 65:291-302
Autor:
Koji Takei, Erik P Pioro, Fumihiro Takahashi, Stephen Apple, Benjamin Rix Brooks, Jeffrey Zhang, Jonathan S. Katz
Publikováno v:
Muscle & Nerve. 65:180-186
Introduction Phase 3 study MCI186-19 demonstrated less loss of physical function with edaravone versus placebo, as measured by the revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R) total score. A 1-point drop in an individual A
Autor:
Michael Pulley, Mikko Kuoppamäki, Carolyn A Young, Jesus S. Mora Pardina, Kumaraswamy Sivakumar, Toni Sarapohja, Michael A. Elliott, Chafic Karam, Sandeep Rana, Orla Hardiman, Nathan P. Staff, Letizia Mazzini, Gabriele Mora, Thomas F. Meyer, Colleen O'Connell, Stéphanie Delstanche, Elham Bayat, Michael D. Weiss, Waqar Waheed, Nenad Mitrovic, Philippe Corcia, Marie-Hélène Soriani, Edward J. Kasarskis, Claudia Caponnetto, Dale J. Lange, Tuan Vu, Leo McCluskey, Berthold Schrank, Angela Genge, Matthew C. Kiernan, Valtteri V Aho, Manu Jokela, Philip Van Damme, Juan F. Vázquez Costa, Maurizio Inghilleri, Wolfgang Löscher, David Schultz, Tero Tapiola, Susanne Petri, Adriano Chiò, Gary L. Pattee, Julian Großkreutz, Ammar Al-Chalabi, Aziz Shaibani, Susan Mathers, Kevin J. Felice, Kimberly Goslin, James Caress, Matthias Boentert, Albert C. Ludolph, Aleksandar Radunovic, Robert D. Henderson, James Wymer, Todd Levine, Jakob Rath, Merrilee Needham, William Camu, Gaurav Guliani, Rune Johansson, Leonard H. van den Berg, Namita Goyal, Mark B. Bromberg, Bjorn Oskarsson, Annie Dionne, Eduardo Locatelli, Brent T. Harris, Suma Babu, Richard Bedlack, John Ravits, Jinsy A. Andrews, Philippe Couratier, Gabriele Siciliano, Hannu Laaksovirta, Kourosh Rezania, Lawrence Korngut, Eduardo Aguera Morales, Peter M Andersen, Eva Farrero Munoz, David Lacomis, Stephen N. Scelsa, Chris Garratt, Matthew Burford, Merit Cudkowicz, Nicholas J. Maragakis, Wendy Johnston, Martin M. Brown, Johannes Prudlo, Justin Y. Kwan, Dominic B. Fee, Senda Ajroud-Driss, Stephen A. Goutman, John Turnbull, Michael H. Rivner, Timothy M. Miller, Jan De Bleecker, Caroline Ingre, Luis Varona, Genevieve Matte, Daragh Heitzman, Robert Untucht, Lorne Zinman, Adam Quick, Jonathan S. Katz
Publikováno v:
The Lancet Neurology. 20:821-831
Summary Background There is an urgent unmet need for new therapies in amyotrophic lateral sclerosis. In a clinical study with healthy volunteers, levosimendan, a calcium sensitiser, was shown to improve neuromechanical efficiency and contractile func
Autor:
Meghan Hall, Janet P. Wittes, Gary L. Pattee, Eric A. Macklin, Eric Tustison, Tuan Vu, Zi-Fan Yu, Samuel P. Dickson, Rudolph E. Tanzi, Liberty Jenkins, Suma Babu, Michael A. Elliott, Jonathan S. Katz, Chafic Karam, Patricia L. Andres, Terry Heiman-Patterson, Stephen N. Scelsa, Christina Fournier, Joseph Ostrow, Timothy M. Miller, Joshua N Cohen, Daragh Heitzman, Edward J. Kasarskis, Derek Dagostino, Patrick D. Yeramian, Colin Quinn, Rebecca Randall, Lindsay Pothier, James Wymer, Hong Yu, Gale Kittle, Newman Knowlton, Michelle McGovern, Shafeeq Ladha, Jason Walker, Jeffrey D. Rothstein, Adam Quick, James Chan, Kent L. Leslie, Prasha Vigneswaran, Maria E. St. Pierre, Kristin M. Johnson, Walter Gilbert, Namita Goyal, James B. Caress, Marianne Chase, Sabrina Paganoni, Jonathan D. Glass, Justin Klee, Merit Cudkowicz, Jeremy M. Shefner, Suzanne Hendrix, Carlayne E. Jackson, Margaret Owegi, James D. Berry, David A. Schoenfeld, Alexander Sherman, Stephen A. Goutman, Matthew Eydinov, Andrea Swenson, Samuel Maiser
Publikováno v:
Muscle & Nerve
An orally administered, fixed‐dose coformulation of sodium phenylbutyrate‐taurursodiol (PB‐TURSO) significantly slowed functional decline in a randomized, placebo‐controlled, phase 2 trial in ALS (CENTAUR). Herein we report results of a long
Autor:
Sumaira Hussain, Jonathan S. Katz, James Caress, David Walk, Nancy Smider, Tom Yosick, Carlayne E. Jackson, Jessica Hernandez, Anne-Laure Grignon, Michael Benatar, Volkan Granit, Joanne Wuu
Publikováno v:
Muscle Nerve
The electronic health record (EHR) is designed principally to support the provision and documentation of clinical care, as well as billing and insurance claims. Broad implementation of the EHR, however, also yields an opportunity to use EHR data for
Publikováno v:
RRNMF Neuromuscular Journal. 1:22-24
Isolated bilateral ptosis as an initial sign of Guillain-Barré Syndrome (GBS) with subsequent limb paralysis or paresis has been reported. However, to our knowledge, bilateral ptosis with subsequent limb myokymia but without ophthalmoplegia, facial
Publikováno v:
Journal of the Neurological Sciences. 397:84-91
To evaluate how neurologists make decisions regarding chronic inflammatory demyelinating polyneuropathy (CIDP), we conducted a cross-sectional quantitative survey of 100 community neurologists in the United States. Only 13% cited using the European F
Autor:
Regina M. Santella, Chafic Karam, Sharon P. Nations, Ghazala Hayat, Yunxia Wang, Laura Herbelin, Maureen Walsh, Heather M. Wilkins, Hiroshi Mitsumoto, Jeffrey Statland, Richard J. Barohn, Tahseen Mozaffar, Jonathan S. Katz, J. Americo Fernandes, Lauren Elman, David Saperstein, Russell H. Swerdlow, Dan H. Moore, Abdulbaki Agbas, Mazen M. Dimachkie
Publikováno v:
Muscle & Nerve. 59:201-207
Introduction Rasagiline is a monoamine oxidase B (MAO-B) inhibitor with possible neuroprotective effects in patients with amyotrophic lateral sclerosis (ALS). Methods We performed a randomized, double-blind, placebo-controlled trial of 80 ALS partici
Autor:
Sonya Fabricius, Kenneth C. Gorson, Richard J. Barohn, Ted M. Burns, Karen Easton, John T. Kissel, Marc Wallis, Richard Dubinsky, Gretchen Ayer, Jeffrey M. Burns, Carlayne E. Jackson, Omar Jawdat, Anthony Amato, Gil I. Wolfe, Joshua Freeman, Todd Levine, Aziz Shaibani, Dave Saperstein, Russel Swerdlow, Mamatha Pasnoor, Tahseen Mozafar, J. Statland, Walter Anderson, Erik R. Ensrud, Mazen M. Dimachkie, Laura Herbelin, Joel Barohn, Jonathan S. Katz
Publikováno v:
RRNMF Neuromuscular Journal. 2