Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Jonathan S. Fisher"'
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 10, Pp 8040-8052 (2023)
Metabolic stress in skeletal muscle cells causes sustained metabolic changes, but the mechanisms of the prolonged effects are not fully known. In this study, we tested C2C12 cells with the AMP-activated protein kinase (AMPK) stimulator AICAR and meas
Externí odkaz:
https://doaj.org/article/c0435aae3aa94c1bb9710df18b7d3ffe
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 261-273 (2022)
Globins constitute an ancient superfamily of proteins, exhibiting enormous structural and functional diversity, as demonstrated by many heme-binding families and two non-heme binding families that were discovered in bacterial stressosome component Rs
Externí odkaz:
https://doaj.org/article/52a3596fabb04ced940320bc71ce8a5f
Publikováno v:
Redox Biology, Vol 27, Iss , Pp - (2019)
The reduction of extracellular oxidants by intracellular electrons is known as trans-plasma membrane electron transport (tPMET). The goal of this study was to characterize a role of tPMET in the sensing of glucose as a physiological signal. tPMET fro
Externí odkaz:
https://doaj.org/article/22e11ebedf6640d2a20621a19d730915
Autor:
Mark H. Mannino, Rishi S. Patel, Amanda M. Eccardt, Blythe E. Janowiak, David C. Wood, Fahu He, Jonathan S. Fisher
Publikováno v:
Antioxidants, Vol 9, Iss 6, p 549 (2020)
Myoglobin (Mb), an oxygen-binding heme protein highly expressed in heart and skeletal muscle, has been shown to undergo oxidative modifications on both an inter- and intramolecular level when exposed to hydrogen peroxide (H2O2) in vitro. Here, we sho
Externí odkaz:
https://doaj.org/article/79efca5a14f14b159e54902ee85d0482
Autor:
Stanley Andrisse, Rikki M. Koehler, Joseph E. Chen, Gaytri D. Patel, Vivek R. Vallurupalli, Benjamin A. Ratliff, Daniel E. Warren, Jonathan S. Fisher
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 764-771 (2014)
In skeletal muscle cells, GLUT1 is responsible for a large portion of basal uptake of glucose and dehydroascorbic acid, both of which play roles in antioxidant defense. We hypothesized that conditions that would decrease GLUT1-mediated transport woul
Externí odkaz:
https://doaj.org/article/d006588b09194e43ae8201c6b1845a7d
Autor:
Larry D. Spears, Andrew V. Tran, Charles Y. Qin, Supriya B. Hobbs, Cheryl A. Liang Burns, Nathaniel K. Royer, Zhihong Zhang, Lyle Ralston, Jonathan S. Fisher
Publikováno v:
Heliyon, Vol 2, Iss 3 (2016)
Aims: There are reports that ataxia telangiectasia mutated (ATM) can activate the AMP-activated protein kinase (AMPK) and also Akt, two kinases that play integral parts in cardioprotection and metabolic function. We hypothesized that chloroquine and
Externí odkaz:
https://doaj.org/article/78b9801cf1df4ce99c1a1b1e468c835d
Autor:
Amanda M. Eccardt, Thomas P. Bell, Lyn Mattathil, Rohan Prasad, Shannon C. Kelly, Jonathan S. Fisher
Publikováno v:
Antioxidants, Vol 6, Iss 4, p 89 (2017)
Trans-plasma membrane electron transport (tPMET) and the antioxidant roles of ascorbate reportedly play a role in protection of cells from damage by reactive oxygen species, which have been implicated in causing metabolic dysfunction such as insulin
Externí odkaz:
https://doaj.org/article/6214ed887a6640e9b4c565864170b37b
Autor:
Sunil M. Kurian, Paul R Lewis, Jamie Case, Christopher L. Marsh, Randolph Schaffer, Steven Steuterman, Mary A. Decoteau, Jonathan S. Fisher
Publikováno v:
Journal of Radiological Protection. 41:N1-N11
Yttrium-90 (Y-90) radioembolization for the treatment of hepatocellular carcinoma can present safety challenges when transplanting recently treated Y-90 patients. To reduce surgeons' contact with radioactive tissue and remain within occupational dose
Autor:
Jonathan S. Fisher, Sunil M. Kurian, Randolph Schaffer, Bethany Barrick, Jamie Case, Alice E. Toll, Elaine F. Reed, Christopher L. Marsh, Michael M. Quigley, James C. Rice, Ryan J. Schutt, Samantha R. Spierling Bagsic, Qiuheng Zhang
Publikováno v:
Transplantation Proceedings. 53:950-961
Although interest in the role of donor-specific antibodies (DSAs) in kidney transplant rejection, graft survival, and histopathological outcomes is increasing, their impact on steroid avoidance or minimization in renal transplant populations is poorl
Autor:
Chiron L.C. Robinson, Rodrigo A. Perez Magnelli, Rishi S. Patel, Mark H. Mannino, Daniel E. Warren, Blythe E. Janowiak, Amanda M. Eccardt, Jonathan S. Fisher
Publikováno v:
Comp Biochem Physiol B Biochem Mol Biol
Myoglobins (Mb) are ubiquitous proteins found in striated muscle of nearly all vertebrate taxa. Although their function is most commonly associated with facilitating oxygen storage and diffusion, Mb has also been implicated in cellular antioxidant de