Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jonathan S. Faris"'
Publikováno v:
Journal of Biological Chemistry. 271:19464-19474
Nuclear hormone receptors bind to hormone response elements in DNA consisting of two half-sites of 6 base pairs. The P-box amino acids of each receptor determine the identities of the central nucleotides of the half-site. 57 P-box variants of the hum
Publikováno v:
International Journal of Legal Medicine. 129:465-466
Allele frequency distributions in the Caymanian population were determined using the AmpFlSTR® Identifiler® PCR amplification kit. Little evidence of departure from Hardy-Weinberg equilibrium or the association of alleles of different loci was dete
Autor:
Guy P. Richardson, Lily Ng, Jonathan S. Faris, Lori L. Amma, Douglas Forrest, Richard J. Goodyear, Iwan Jones
Publikováno v:
Molecular and cellular neurosciences. 23(3)
The precise movement of the cochlear basilar membrane (BM) stimulates the sensory hair cells during auditory transduction. However, the molecular composition of the BM that confers its specialized properties of support and elasticity is poorly unders
Autor:
Lori L. Amma, Douglas Forrest, Matthew W. Kelley, Jonathan S. Faris, Ranu Shailam, Angel Campos-Barros
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 97(3)
Thyroid hormone signaling during a postnatal period in the mouse is essential for cochlear development and the subsequent onset of hearing. To study the control of this temporal dependency, we investigated the role of iodothyronine deiodinases, which
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 8(7)
Three "P-box" amino acids within the DNA recognition alpha-helix of members of the steroid hormone and thyroid hormone families of nuclear receptors are known to determine the identity of two of the six base pairs within the half-sites of cognate DNA
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 7(9)
The roles in DNA binding and transcriptional activation of individual amino acids in the putative recognition alpha-helix of the first zinc finger of the beta-isoform of the human thyroid hormone receptor (hT3R beta) have been probed by site-directed