Zobrazeno 1 - 10
of 516
pro vyhledávání: '"Jonathan S. Dordick"'
Autor:
Rebecca T. Miceli, Noah G. Allen, Bhagyashree Subramaniam, Livia Carmody, Jonathan S. Dordick, David T. Corr, Myriam Cotten, Richard A. Gross
Publikováno v:
ACS Omega, Vol 9, Iss 31, Pp 33408-33424 (2024)
Externí odkaz:
https://doaj.org/article/edefa93177c14a9ea92aceab82344fb0
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109186- (2024)
Summary: Magnetogenetics represents a method for remote control of cellular function. Previous work suggests that generation of reactive oxygen species (ROS) initiates downstream signaling. Herein, a chemical biology approach was used to elucidate fu
Externí odkaz:
https://doaj.org/article/60e6d65975824a90aa6e7c8cc7e14917
Autor:
Manuel Castro Berman, Allison R. Hrycik, Angelica Costello, Yang Bai, Kevin C. Rose, Rick Relyea, Jonathan S. Dordick
Publikováno v:
Ecological Indicators, Vol 159, Iss , Pp 111738- (2024)
Understanding spatial and temporal heterogeneity in ecosystems is essential to forecasting the effects of environmental changes. Freshwater microbes, including cyanobacteria, play a crucial role in food-web structures and biochemical processes, yet c
Externí odkaz:
https://doaj.org/article/3f48e18698974d248d49e2c60bb68da4
Autor:
Jiyuan Yang, Yuefan Song, Ke Xia, Vitor H. Pomin, Chunyu Wang, Mingqiang Qiao, Robert J. Linhardt, Jonathan S. Dordick, Fuming Zhang
Publikováno v:
Marine Drugs, Vol 22, Iss 5, p 232 (2024)
Mycoplasma pneumoniae, a notable pathogen behind respiratory infections, employs specialized proteins to adhere to the respiratory epithelium, an essential process for initiating infection. The role of glycosaminoglycans, especially heparan sulfate,
Externí odkaz:
https://doaj.org/article/67ebfea3f0544ab5bdfa9a3a29c24e5e
Autor:
Paul S. Kwon, Shirley Xu, Hanseul Oh, Seok-Joon Kwon, Andre L. Rodrigues, Maisha Feroz, Keith Fraser, Peng He, Fuming Zhang, Jung Joo Hong, Robert J. Linhardt, Jonathan S. Dordick
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Suramin, a polysulfated synthetic drug, binds to the ACE2 receptor and heparan sulfate binding sites on SARS-CoV-2 RBDs with preferential binding for Omicron RBD and inhibition of infection by the Omicron variant in vitro.
Externí odkaz:
https://doaj.org/article/f9c4ce0ff01c4a649d774200f246e2fd
Autor:
Bhanushee Sharma, Vijil Chenthamarakshan, Amit Dhurandhar, Shiranee Pereira, James A. Hendler, Jonathan S. Dordick, Payel Das
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Explainable machine learning for molecular toxicity prediction is a promising approach for efficient drug development and chemical safety. A predictive ML model of toxicity can reduce experimental cost and time while mitigating ethical conce
Externí odkaz:
https://doaj.org/article/90011f1b0e144c0483392cab2a7862e4
Autor:
Jiyuan Yang, Yuefan Song, Weihua Jin, Ke Xia, Grace C. Burnett, Wanjin Qiao, John T. Bates, Vitor H. Pomin, Chunyu Wang, Mingqiang Qiao, Robert J. Linhardt, Jonathan S. Dordick, Fuming Zhang
Publikováno v:
Viruses, Vol 16, Iss 2, p 237 (2024)
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus with high contagion and mortality rates. Heparan sulfate proteoglycans (HSPGs) are ubiquitously expressed on the surface of mammalian cells. Owing to its high negatively char
Externí odkaz:
https://doaj.org/article/a85e0c11f5ad435dbfcfef4089272a77
Autor:
Deling Shi, Peng He, Yuefan Song, Robert J. Linhardt, Jonathan S. Dordick, Lianli Chi, Fuming Zhang
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: The unexpected surge of respiratory syncytial virus (RSV) cases following pandemic phase of COVID-19 has drawn much public attention. Drawing on the latest antiviral research, revisiting this heightened annual outbreak of respiratory di
Externí odkaz:
https://doaj.org/article/5c07cb5c2fdd485d8d24e10316bafc3d
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSustained neuroinflammation is a major contributor to the progression of neurodegenerative diseases such as Alzheimer’s (AD) and Parkinson’s (PD) diseases. Neuroinflammation, like other cellular processes, is affected by the circadian
Externí odkaz:
https://doaj.org/article/28e0e1d5665f4796b26a416da821bf52
Autor:
Kriti Kapil, Shirley Xu, Inseon Lee, Hironobu Murata, Seok-Joon Kwon, Jonathan S. Dordick, Krzysztof Matyjaszewski
Publikováno v:
Polymers, Vol 15, Iss 12, p 2723 (2023)
Infectious diseases caused by pathogens are a health burden, but traditional pathogen identification methods are complex and time-consuming. In this work, we have developed well-defined, multifunctional copolymers with rhodamine B dye synthesized by
Externí odkaz:
https://doaj.org/article/44e0573cdad54635bf5884718dbbbc8a