Zobrazeno 1 - 10
of 347
pro vyhledávání: '"Jonathan S, Stamler"'
Autor:
Nicholas M. Venetos, Colin T. Stomberski, Zhaoxia Qian, Richard T. Premont, Jonathan S. Stamler
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 5, Pp 100542- (2024)
Nitric oxide (NO), produced primarily by nitric oxide synthase enzymes, is known to influence energy metabolism by stimulating fat uptake and oxidation. The effects of NO on de novo lipogenesis (DNL), however, are less clear. Here we demonstrate that
Externí odkaz:
https://doaj.org/article/3cc03f53e51e45339f1a1a0980076d37
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102430- (2023)
Summary: S-nitrosothiol (SNO)-Resin Assisted Capture (SNO-RAC) relies on a Thiopropyl Sepharose resin to identify S-nitrosylated proteins (SNO-proteins) and sites of S-nitrosylation. Here, we present a protocol for preparing Thiopropyl Sepharose resi
Externí odkaz:
https://doaj.org/article/326719b1f07647af88ef334e100a4cfc
Autor:
John T. Hancock, Grace Russell, Tim J. Craig, Jennifer May, H. Ruth Morse, Jonathan S. Stamler
Publikováno v:
Oxygen, Vol 2, Iss 4, Pp 578-590 (2022)
Hydrogen gas (molecular hydrogen, H2) has significant effects in a range of organisms, from plants to humans. Many inert gases have been reported to have similar effects, and such responses may be most pronounced when cells are stressed. Xenon (Xe),
Externí odkaz:
https://doaj.org/article/c331ef61aa2043b596d2442ad98d7780
Autor:
Ryan Nazemian, Maroun Matta, Amer Aldamouk, Lin Zhu, Mohamed Awad, Megan Pophal, Nicole R. Palmer, Tonya Armes, Alfred Hausladen, Jonathan S. Stamler, James D. Reynolds
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Current human donor care protocols following death by neurologic criteria (DNC) can stabilize macro-hemodynamic parameters but have minimal ability to preserve systemic blood flow and microvascular oxygen delivery. S-nitrosylated hemoglobin
Externí odkaz:
https://doaj.org/article/74a4b1c6ee4b4d37b7fb5f4398f4978e
Autor:
Rongli Zhang, Alfred Hausladen, Zhaoxia Qian, Xudong Liao, Richard T. Premont, Jonathan S. Stamler
Publikováno v:
JCI Insight, Vol 7, Iss 3 (2022)
Systemic hypoxia is characterized by peripheral vasodilation and pulmonary vasoconstriction. However, the system-wide mechanism for signaling hypoxia remains unknown. Accumulating evidence suggests that hemoglobin (Hb) in RBCs may serve as an O2 sens
Externí odkaz:
https://doaj.org/article/65ec0b327e2144c8a3a56c4409e37220
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100547- (2021)
Summary: Post-translational modification by S-nitrosylation regulates numerous cellular functions and impacts most proteins across phylogeny. We describe a protocol for isolating S-nitrosylated proteins (SNO-proteins) from C. elegans, suitable for as
Externí odkaz:
https://doaj.org/article/53735b47ff124f3a8cab49ba24758e9a
Autor:
Hua-Lin Zhou, Alfred Hausladen, Puneet Anand, Malligarjunan Rajavel, Colin T. Stomberski, Rongli Zhang, Richard T. Premont, William J. Greenlee, Focco van den Akker, Jonathan S. Stamler
Publikováno v:
Journal of Medicinal Chemistry. 66:5657-5668
Autor:
Megan Pophal, Zachary W. Grimmett, Clara Chu, Seunghee Margevicius, Thomas Raffay, Kristie Ross, Anjum Jafri, Olivia Giddings, Jonathan S. Stamler, Benjamin Gaston, James D. Reynolds
Publikováno v:
Antioxidants, Vol 10, Iss 10, p 1527 (2021)
Thiol-NO adducts such as S-nitrosoglutathione (GSNO) are endogenous bronchodilators in human airways. Decreased airway S-nitrosothiol concentrations are associated with asthma. Nitric oxide (NO), a breakdown product of GSNO, is measured in exhaled br
Externí odkaz:
https://doaj.org/article/d1a130a4543a4d1bb3d6263a060b364e
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 382:1-10
Autor:
Divya Seth, Colin T. Stomberski, Precious J. McLaughlin, Richard T Premont, Kathleen Lundberg, Jonathan S Stamler
Publikováno v:
Antioxidants & Redox Signaling.