Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jonathan Ryves"'
Autor:
Jason King, Melanie Keim, Regina Teo, Karin E Weening, Mridu Kapur, Karina McQuillan, Jonathan Ryves, Ben Rogers, Emma Dalton, Robin S B Williams, Adrian J Harwood
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11151 (2010)
Lithium (Li(+)) is a common treatment for bipolar mood disorder, a major psychiatric illness with a lifetime prevalence of more than 1%. Risk of bipolar disorder is heavily influenced by genetic predisposition, but is a complex genetic trait and, to
Externí odkaz:
https://doaj.org/article/49baaca3187a4a04bd08a67aaae112cf
Autor:
Huw Jones, Dylan Phillips, Jonathan Ryves, Daniel Fenton, Anne Louise Maddison, Christopher H. George
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Cell permeating peptides (CPPs) are attracting great interest for use as molecular delivery vehicles for the transport of biologically active cargo across the cell membrane. The sequence of a novel CPP sequence, termed ‘Cupid’, was identified fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec37527c0b3aacb81bfbc69e9616a0ed
https://cronfa.swan.ac.uk/Record/cronfa54856/Download/54856__18178__70e76befe1124bc59374ad4481083a7c.pdf
https://cronfa.swan.ac.uk/Record/cronfa54856/Download/54856__18178__70e76befe1124bc59374ad4481083a7c.pdf
Autor:
Jonathan Ryves, W1 (AUTHOR), Dalton, Emma C1 (AUTHOR), Harwood, Adrian J1 (AUTHOR), Williams, Robin SB2 (AUTHOR)
Publikováno v:
Bipolar Disorders. Jun2005, Vol. 7 Issue 3, p260-265. 6p.
Autor:
Robin S.B. Williams, Oliver Hoeller, Adrian J. Harwood, Regina Teo, Jonathan Ryves, Owen M. Peters, Ben Orabi, Jason S. King, Jonathan Venkat Reddy
Publikováno v:
Disease Models & Mechanisms. 2:306-312
SUMMARY Bipolar mood disorder (manic depression) is a major psychiatric disorder whose molecular origins are unknown. Mood stabilisers offer patients both acute and prophylactic treatment, and experimentally, they provide a means to probe the underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05704363560bdb747e764b8cde97948c
https://doi.org/10.1242/dmm.001271
https://doi.org/10.1242/dmm.001271
Autor:
W. Jonathan Ryves, Adrian J. Harwood
Publikováno v:
Molecular Biotechnology. 33:123-132
The plasma membrane is an effective barrier to most macromolecules and hydrophilic molecules. Remarkably, a class of positively charged cell-penetrating peptides (CPPs) has been discovered that can translocate themselves and associated cargoes into t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8674656f7ff0d1a6337a63a958f657
https://doi.org/10.1385/mb:33:2:123
https://doi.org/10.1385/mb:33:2:123
Publikováno v:
Bipolar Disorders. 7:260-265
Objectives: Lithium (Li+) has been suggested to target the enzyme glycogen synthase kinase 3 (GSK-3) as a mechanism of mood stabilization. Inhibition of GSK-3 by a second mood-stabilizer, valproic acid (VPA), has also been reported, but this effect i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb857add181432445120ac9565bc681
https://doi.org/10.1111/j.1399-5618.2005.00194.x
https://doi.org/10.1111/j.1399-5618.2005.00194.x
Autor:
Jonathan Ryves, Matthew J. Smalley, Adrian J. Harwood, Marie-Therese Webster, Robin S.B. Williams, Trevor Clive Dale, Margaret Yeo, Rana Dajani, Elizabeth Fraser, Christopher A. Richardson, Neville Young, Laurence H. Pearl, Jonathan Franca-Koh
Publikováno v:
Journal of Biological Chemistry. 277:2176-2185
Glycogen synthase kinase-3 (GSK-3) is a key component of several signaling pathways including those regulated by Wnt and insulin ligands. Specificity in GSK-3 signaling is thought to involve interactions with scaffold proteins that localize GSK-3 reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a1def7066b7355adee5876800bd763
https://doi.org/10.1074/jbc.m109462200
https://doi.org/10.1074/jbc.m109462200
Autor:
Adrian J. Harwood, Mridu Kapur, Melanie Keim, Karina McQuillan, Robin S.B. Williams, Jonathan Ryves, Karin E. Weening, Emma Dalton, Regina Teo, Ben Rogers, Jason S. King
Publikováno v:
PLoS One, 5 (6)
PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e11151 (2010)
PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e11151 (2010)
Lithium (Li(+)) is a common treatment for bipolar mood disorder, a major psychiatric illness with a lifetime prevalence of more than 1%. Risk of bipolar disorder is heavily influenced by genetic predisposition, but is a complex genetic trait and, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e058e1a9c3a977285127ac45d2250f2
https://repository.royalholloway.ac.uk/items/f3d441f9-de40-d036-f9cd-5d573b26e4ea/6/
https://repository.royalholloway.ac.uk/items/f3d441f9-de40-d036-f9cd-5d573b26e4ea/6/
Autor:
William Jonathan Ryves, Adrian J. Harwood, Regina Teo, Kimberley Lewis, Benjamin James Rogers, Josephine E. Forde, Jonathan Venkat Reddy
Publikováno v:
Molecular Biology of the Cell
We present a new role for glycogen synthase kinase (GSK) in the regulation of aggregation and chemotaxis in Dictyostelium. GSK regulates two chemotactic pathways, PIP3 and TORC2; hence, a loss of function of GSK leads to poor chemotaxis, an observati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d027bcbcb2a0abc30c6491fc59a37005
Autor:
Michael J. Clemens, Shaun Thomas, Juan Menaya, Kati Hudson, Vinod Devalia, Fred J. Evans, Jonathan Ryves, Robert I. James
Publikováno v:
European Journal of Biochemistry. 209:813-822
Recent studies have suggested that protein kinase C (PKC) may be involved in the mechanism of signal transduction by which members of the interferon (IFN) family regulate gene expression and cell phenotype. We have investigated the role of PKC in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9421b9a8c4a604fcdac8f3e97010f3
https://doi.org/10.1111/j.1432-1033.1992.tb17352.x
https://doi.org/10.1111/j.1432-1033.1992.tb17352.x