Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jonathan R. T. Jeffers"'
Autor:
Stylianos Kechagias, Konstantinos Theodoridis, Joseph Broomfield, Kenny Malpartida-Cardenas, Ruth Reid, Pantelis Georgiou, Richard J. van Arkel, Jonathan R. T. Jeffers
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Modern orthopaedic implants use lattice structures that act as 3D scaffolds to enhance bone growth into and around implants. Stochastic scaffolds are of particular interest as they mimic the architecture of trabecular bone and can combine isotropic p
Externí odkaz:
https://doaj.org/article/7eba9594a36a4ad0b1faa685b93d50df
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The aim of this study was to develop an automated pipeline capable of designing custom total knee replacement implants from CT scans. The developed pipeline firstly utilised a series of machine learning methods including classification, obje
Externí odkaz:
https://doaj.org/article/e0a8b6d0d0a24127a54663c07bd47f14
Autor:
Maxwell J. Munford, Jennifer C. Stoddart, Alexander D. Liddle, Justin P. Cobb, Jonathan R. T. Jeffers
Publikováno v:
Bone & Joint Research, Vol 11, Iss 2, Pp 91-101 (2022)
Aims Unicompartmental and total knee arthroplasty (UKA and TKA) are successful treatments for osteoarthritis, but the solid metal implants disrupt the natural distribution of stress and strain which can lead to bone loss over time. This generates pro
Externí odkaz:
https://doaj.org/article/f0d624c464124f0fab3e60edbe39ab35
Autor:
Kabelan J. Karunaseelan, Oliver Dandridge, Sarah K. Muirhead-Allwood, Richard J. van Arkel, Jonathan R. T. Jeffers
Publikováno v:
Bone & Joint Research, Vol 10, Iss 9, Pp 594-601 (2021)
Aims: In the native hip, the hip capsular ligaments tighten at the limits of range of hip motion and may provide a passive stabilizing force to protect the hip against edge loading. In this study we quantified the stabilizing force vectors generated
Externí odkaz:
https://doaj.org/article/5d9eb24de355451898ca78eefec02f99
Autor:
Øystein Øvrebø, Giuseppe Perale, Jonathan P. Wojciechowski, Cécile Echalier, Jonathan R. T. Jeffers, Molly M. Stevens, Håvard J. Haugen, Filippo Rossi
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 2, Pp n/a-n/a (2022)
Abstract Musculoskeletal defects are an enormous healthcare burden and source of pain and disability for individuals. With an aging population, the proportion of individuals living with these medical indications will increase. Simultaneously, there i
Externí odkaz:
https://doaj.org/article/33983d573e9e499893d9fb21324b1ee6
Autor:
Jeffrey N. Clark, Saman Tavana, Agathe Heyraud, Francesca Tallia, Julian R. Jones, Ulrich Hansen, Jonathan R. T. Jeffers
Publikováno v:
Materials, Vol 13, Iss 17, p 3890 (2020)
Regenerative medicine solutions require thoughtful design to elicit the intended biological response. This includes the biomechanical stimulus to generate an appropriate strain in the scaffold and surrounding tissue to drive cell lineage to the desir
Externí odkaz:
https://doaj.org/article/2f1df3bc77114ff5b349073b33b47949
Autor:
Jeffrey N. Clark, Agathe Heyraud, Saman Tavana, Talal Al-Jabri, Francesca Tallia, Brett Clark, Gordon W. Blunn, Justin P. Cobb, Ulrich Hansen, Julian R. Jones, Jonathan R. T. Jeffers
Publikováno v:
Materials, Vol 13, Iss 18, p 3911 (2020)
Osteochondral injuries are increasingly prevalent, yet success in articular cartilage regeneration remains elusive, necessitating the development of new surgical interventions and novel medical devices. As part of device development, animal models ar
Externí odkaz:
https://doaj.org/article/6fbc958c39544e6ea83fbe6bbec4a7d4
Autor:
Thomas A. Burge, Maxwell J. Munford, Stylianos Kechagias, Jonathan R. T. Jeffers, Connor W. Myant
Publikováno v:
The International Journal of Advanced Manufacturing Technology. 126:3725-3737
Autor:
Thomas A, Burge, Gareth G, Jones, Christopher M, Jordan, Jonathan R T, Jeffers, Connor W, Myant
Publikováno v:
Frontiers in Bioengineering and Biotechnology. 10
Purpose: The aim of this study was to outline a fully automatic tool capable of reliably predicting the most suitable total knee replacement implant sizes for patients, using bi-planar X-ray images. By eliminating the need for manual templating or gu
Publikováno v:
Journal of Medical Devices. 16
The objective of this study was to outline a fully automated, X-ray-based, mass-customization pipeline for knee replacement surgery, thoroughly evaluate its robustness across a range of demographics, and quantify necessary input requirements. The pip