Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jonathan R. Chabon"'
Autor:
S. Haihua Chu, Jonathan R. Chabon, Chloe N. Matovina, Janna C. Minehart, Bo-Ruei Chen, Jian Zhang, Vipul Kumar, Yijun Xiong, Elsa Callen, Putzer J. Hung, Zhaohui Feng, Richard P. Koche, X. Shirley Liu, Jayanta Chaudhuri, Andre Nussenzweig, Barry P. Sleckman, Scott A. Armstrong
Publikováno v:
iScience, Vol 23, Iss 3, Pp - (2020)
Summary: Repair of DNA double-stranded breaks (DSBs) during lymphocyte development is essential for V(D)J recombination and forms the basis of immunoglobulin variable region diversity. Understanding of this process in lymphogenesis has historically b
Externí odkaz:
https://doaj.org/article/7b6e87225d7445a5aff36d4d395224c3
Autor:
S Haihua, Chu, Evelyn J, Song, Jonathan R, Chabon, Janna, Minehart, Chloe N, Matovina, Jessica L, Makofske, Elizabeth S, Frank, Kenneth, Ross, Richard P, Koche, Zhaohui, Feng, Haiming, Xu, Andrei, Krivtsov, Andre, Nussenzweig, Scott A, Armstrong
Publikováno v:
Blood advances. 2(19)
Mll-Af4 and mutant N-Ras cooperate to generate an aggressive B-acute lymphoblastic leukemia murine model, recapitulating human disease.Combination MEK and ATR inhibitor treatment of Mll-Af4/N-Ras leukemia induces synergistic antileukemic effects in v