Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jonathan R Roth"'
Autor:
Jonathan R. Roth, Ruan Carlos Macedo de Moraes, Brittney P. Xu, Savannah R. Crawley, Malghalara A. Khan, Girish C. Melkani
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Huntington’s disease (HD) is a neurodegenerative disease characterized by movement and cognitive dysfunction. HD is caused by a CAG expansion in exon 1 of the HTT gene that leads to a polyglutamine (PQ) repeat in the huntingtin protein, which aggre
Externí odkaz:
https://doaj.org/article/798592d43c794b8684d6333d9ac38cd5
Autor:
Andrew E. Arrant, Jonathan R. Roth, Nicholas R. Boyle, Shreya N. Kashyap, Madelyn Q. Hoffmann, Charles F. Murchison, Eliana Marisa Ramos, Alissa L. Nana, Salvatore Spina, Lea T. Grinberg, Bruce L. Miller, William W. Seeley, Erik D. Roberson
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract Loss-of-function mutations in progranulin (GRN) are a major autosomal dominant cause of frontotemporal dementia. Most pathogenic GRN mutations result in progranulin haploinsufficiency, which is thought to cause frontotemporal dementia in GRN
Externí odkaz:
https://doaj.org/article/c318266701f74db1b7c84975e46849dc
Publikováno v:
Obesity. 31:40-49
Autor:
Yuliya Voskobiynyk, Jonathan R Roth, J Nicholas Cochran, Travis Rush, Nancy VN Carullo, Jacob S Mesina, Mohammad Waqas, Rachael M Vollmer, Jeremy J Day, Lori L McMahon, Erik D Roberson
Publikováno v:
eLife, Vol 9 (2020)
Genome-wide association studies identified the BIN1 locus as a leading modulator of genetic risk in Alzheimer’s disease (AD). One limitation in understanding BIN1’s contribution to AD is its unknown function in the brain. AD-associated BIN1 varia
Externí odkaz:
https://doaj.org/article/97be4c7738104900994a17115fbcacfb
Autor:
Travis Rush, Jonathan R. Roth, Samantha J. Thompson, Adam R. Aldaher, J. Nicholas Cochran, Erik D. Roberson
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
The microtubule-associated protein Tau is strongly implicated in Alzheimer's disease (AD) and aggregates into neurofibrillary tangles in AD. Genetic reduction of Tau is protective in several animal models of AD and cell culture models of amyloid-β (
Externí odkaz:
https://doaj.org/article/58995778edfc4af4b8e1cc0a3d2a0f3a
Autor:
Shreya N. Kashyap, Erik D. Roberson, Lea T. Grinberg, Madelyn Q. Hoffmann, William W. Seeley, Andrew E. Arrant, Jonathan R. Roth, Alissa L. Nana, Bruce L. Miller, Eliana Marisa Ramos, Charles F. Murchison, Salvatore Spina, Nicholas R. Boyle
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-17 (2019)
Acta Neuropathologica Communications
Acta neuropathologica communications, vol 7, iss 1
Acta Neuropathologica Communications
Acta neuropathologica communications, vol 7, iss 1
Loss-of-function mutations in progranulin (GRN) are a major autosomal dominant cause of frontotemporal dementia. Most pathogenicGRNmutations result in progranulin haploinsufficiency, which is thought to cause frontotemporal dementia inGRNmutation car
Autor:
Jonathan R Roth, Travis Rush, Derian A Pugh, Hunter B Dean, J. Nicholas Cochran, Samantha J Thompson, Adam R Aldaher, Jacob S Mesina, Pedro Ruiz, Vibha Pathak, Mousheng Wu, J Robert Bostwick, Mark J Suto, Corinne E Augelli‐Szafran, Erik D. Roberson
Publikováno v:
Alzheimer's & Dementia. 17
Autor:
Jonathan R, Roth, Cristin F, Gavin
Publikováno v:
J Undergrad Neurosci Educ
This article details an antiracism exercise completed in an introductory undergraduate neuroscience class. Students completed an online pre-class multimedia module entitled “Race and the Ivory Tower” covering racism in science and medicine, the n
Autor:
Lori L. McMahon, Travis Rush, Rachael M Vollmer, Yuliya Voskobiynyk, J. Nicholas Cochran, Nancy V. N. Carullo, Erik D. Roberson, Jonathan R. Roth, Jeremy J. Day, Mohammad Waqas
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Lori L. McMahon, Nancy V. N. Carullo, J. N. Cochran, Travis Rush, Jacob S Mesina, Yuliya Voskobiynyk, Rachael M Vollmer, Jeremy J. Day, Mohammad Waqas, Erik D. Roberson, Jonathan R. Roth
Publikováno v:
eLife, Vol 9 (2020)
Genome-wide association studies identified the BIN1 locus as a leading modulator of genetic risk in Alzheimer’s disease (AD). One limitation in understanding BIN1’s contribution to AD is its unknown function in the brain. AD-associated BIN1 varia