Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Jonathan R I, Coleman"'
Autor:
Royce E. Clifford, Adam X. Maihofer, Chris Chatzinakos, Jonathan R. I. Coleman, Nikolaos P. Daskalakis, Marianna Gasperi, Kelleigh Hogan, Elizabeth A. Mikita, Murray B. Stein, Catherine Tcheandjieu, Francesca Telese, Yanning Zuo, Allen F. Ryan, Caroline M. Nievergelt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Tinnitus is a heritable, highly prevalent auditory disorder treated by multiple medical specialties. Previous GWAS indicated high genetic correlations between tinnitus and hearing loss, with little indication of differentiating signals. We p
Externí odkaz:
https://doaj.org/article/30de7f1a439945cab2722d0a874ce2a8
Autor:
Saloni Dattani, Pak C. Sham, Bradley S. Jermy, Jonathan R. I. Coleman, David M. Howard, Cathryn M. Lewis
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Genetic studies in psychiatry have primarily focused on the effects of common genetic variants, but few have investigated the role of rare genetic variants, particularly for major depression. In order to explore the role of rare variants in
Externí odkaz:
https://doaj.org/article/d7ac31e74fc54730b0a4c98f699c8bf2
Autor:
Veera M. Rajagopal, Andrea Ganna, Jonathan R. I. Coleman, Andrea Allegrini, Georgios Voloudakis, Jakob Grove, Thomas D. Als, Henriette T. Horsdal, Liselotte Petersen, Vivek Appadurai, Andrew Schork, Alfonso Buil, Cynthia M. Bulik, Jonas Bybjerg-Grauholm, Marie Bækvad-Hansen, David M. Hougaard, Ole Mors, Merete Nordentoft, Thomas Werge, iPSYCH-Broad Consortium, Preben Bo Mortensen, Gerome Breen, Panos Roussos, Robert Plomin, Esben Agerbo, Anders D. Børglum, Ditte Demontis
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Cognitive functions of individuals with psychiatric disorders differ from that of the general population. Such cognitive differences often manifest early in life as differential school performance and have a strong genetic basis. Here we mea
Externí odkaz:
https://doaj.org/article/ed05f0cb3a754525a813a4518791dddd
Autor:
Ken B. Hanscombe, Elodie Persyn, Matthew Traylor, Kylie P. Glanville, Mark Hamer, Jonathan R. I. Coleman, Cathryn M. Lewis
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-19 (2021)
Abstract Background Cardiorespiratory fitness (CRF) and physical activity (PA) are well-established predictors of morbidity and all-cause mortality. However, CRF is not routinely measured and PA not routinely prescribed as part of standard healthcare
Externí odkaz:
https://doaj.org/article/619993f082df4c9d9a4ad56bdd0a416a
Autor:
Bradley S. Jermy, Saskia Hagenaars, Jonathan R. I. Coleman, Evangelos Vassos, Cathryn M. Lewis
Publikováno v:
BJPsych Open, Vol 8 (2022)
Background Progress towards understanding the aetiology of major depression is compromised by its clinical heterogeneity. The variety of contexts underlying the development of a major depressive episode may contribute to such heterogeneity. Aims To
Externí odkaz:
https://doaj.org/article/f26611c2893944cca26ecff12f98462a
Autor:
Christopher Hübel, Héléna A. Gaspar, Jonathan R. I. Coleman, Ken B. Hanscombe, Kirstin Purves, Inga Prokopenko, Mariaelisa Graff, Julius S. Ngwa, Tsegaselassie Workalemahu, ADHD Working Group of the Psychiatric Genomics Consortium, Meta-Analyses of Glucose and Insulin-related traits consortium (MAGIC), Autism Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, OCD & Tourette Syndrome Working Group of the Psychiatric Genomics Consortium, PTSD Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross Disorder Working Group of the Psychiatric Genomics Consortium, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, International Headache Genetics Consortium, Paul F. O’Reilly, Cynthia M. Bulik, Gerome Breen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Psychiatric disorders are often accompanied by alterations in BMI and body composition due to changes in eating behaviour and physical activity. Here, Hübel et al. study the genetic overlap between these traits and find that genetic correlations bet
Externí odkaz:
https://doaj.org/article/863cf5db36a34aa2af52cbcbf3287303
Autor:
Christopher Rayner, Jonathan R. I. Coleman, Kirstin L. Purves, Ewan Carr, Rosa Cheesman, Molly R. Davies, Jaime Delgadillo, Christopher Hübel, Georgina Krebs, Alicia J. Peel, Megan Skelton, Gerome Breen, Thalia C. Eley
Publikováno v:
BJPsych Open, Vol 7 (2021)
Background Anxiety and depressive disorders can be chronic and disabling. Although there are effective treatments, only a fraction of those impaired receive treatment. Predictors of treatment-seeking and treatment receipt could be informative for ini
Externí odkaz:
https://doaj.org/article/3df8d9e4c70b4075a0de0564611b543d
Autor:
Jennifer A. Sumner, Adam X. Maihofer, Vasiliki Michopoulos, Alex O. Rothbaum, Lynn M. Almli, Ole A. Andreassen, Allison E. Ashley-Koch, Dewleen G. Baker, Jean C. Beckham, Bekh Bradley, Gerome Breen, Jonathan R. I. Coleman, Anders M. Dale, Michelle F. Dennis, Norah C. Feeny, Carol E. Franz, Melanie E. Garrett, Charles F. Gillespie, Guia Guffanti, Michael A. Hauser, Sian M. J. Hemmings, Tanja Jovanovic, Nathan A. Kimbrel, William S. Kremen, Bruce R. Lawford, Mark W. Logue, Adriana Lori, Michael J. Lyons, Jessica Maples-Keller, Matig R. Mavissakalian, Regina E. McGlinchey, Divya Mehta, Rebecca Mellor, William Milberg, Mark W. Miller, Charles Phillip Morris, Matthew S. Panizzon, Kerry J. Ressler, Victoria B. Risbrough, Barbara O. Rothbaum, Peter Roy-Byrne, Soraya Seedat, Alicia K. Smith, Jennifer S. Stevens, Leigh Luella van den Heuvel, Joanne Voisey, Ross McD Young, Lori A. Zoellner, Caroline M. Nievergelt, Erika J. Wolf
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Growing research suggests that posttraumatic stress disorder (PTSD) may be a risk factor for poor cardiovascular health, and yet our understanding of who might be at greatest risk of adverse cardiovascular outcomes after trauma is limited. In this st
Externí odkaz:
https://doaj.org/article/9ef146f5ca404702a0218c13603f37a4
Autor:
Caroline M. Nievergelt, Adam X. Maihofer, Torsten Klengel, Elizabeth G. Atkinson, Chia-Yen Chen, Karmel W. Choi, Jonathan R. I. Coleman, Shareefa Dalvie, Laramie E. Duncan, Joel Gelernter, Daniel F. Levey, Mark W. Logue, Renato Polimanti, Allison C. Provost, Andrew Ratanatharathorn, Murray B. Stein, Katy Torres, Allison E. Aiello, Lynn M. Almli, Ananda B. Amstadter, Søren B. Andersen, Ole A. Andreassen, Paul A. Arbisi, Allison E. Ashley-Koch, S. Bryn Austin, Esmina Avdibegovic, Dragan Babić, Marie Bækvad-Hansen, Dewleen G. Baker, Jean C. Beckham, Laura J. Bierut, Jonathan I. Bisson, Marco P. Boks, Elizabeth A. Bolger, Anders D. Børglum, Bekh Bradley, Megan Brashear, Gerome Breen, Richard A. Bryant, Angela C. Bustamante, Jonas Bybjerg-Grauholm, Joseph R. Calabrese, José M. Caldas- de- Almeida, Anders M. Dale, Mark J. Daly, Nikolaos P. Daskalakis, Jürgen Deckert, Douglas L. Delahanty, Michelle F. Dennis, Seth G. Disner, Katharina Domschke, Alma Dzubur-Kulenovic, Christopher R. Erbes, Alexandra Evans, Lindsay A. Farrer, Norah C. Feeny, Janine D. Flory, David Forbes, Carol E. Franz, Sandro Galea, Melanie E. Garrett, Bizu Gelaye, Elbert Geuze, Charles Gillespie, Aferdita Goci Uka, Scott D. Gordon, Guia Guffanti, Rasha Hammamieh, Supriya Harnal, Michael A. Hauser, Andrew C. Heath, Sian M. J. Hemmings, David Michael Hougaard, Miro Jakovljevic, Marti Jett, Eric Otto Johnson, Ian Jones, Tanja Jovanovic, Xue-Jun Qin, Angela G. Junglen, Karen-Inge Karstoft, Milissa L. Kaufman, Ronald C. Kessler, Alaptagin Khan, Nathan A. Kimbrel, Anthony P. King, Nastassja Koen, Henry R. Kranzler, William S. Kremen, Bruce R. Lawford, Lauren A. M. Lebois, Catrin E. Lewis, Sarah D. Linnstaedt, Adriana Lori, Bozo Lugonja, Jurjen J. Luykx, Michael J. Lyons, Jessica Maples-Keller, Charles Marmar, Alicia R. Martin, Nicholas G. Martin, Douglas Maurer, Matig R. Mavissakalian, Alexander McFarlane, Regina E. McGlinchey, Katie A. McLaughlin, Samuel A. McLean, Sarah McLeay, Divya Mehta, William P. Milberg, Mark W. Miller, Rajendra A. Morey, Charles Phillip Morris, Ole Mors, Preben B. Mortensen, Benjamin M. Neale, Elliot C. Nelson, Merete Nordentoft, Sonya B. Norman, Meaghan O’Donnell, Holly K. Orcutt, Matthew S. Panizzon, Edward S. Peters, Alan L. Peterson, Matthew Peverill, Robert H. Pietrzak, Melissa A. Polusny, John P. Rice, Stephan Ripke, Victoria B. Risbrough, Andrea L. Roberts, Alex O. Rothbaum, Barbara O. Rothbaum, Peter Roy-Byrne, Ken Ruggiero, Ariane Rung, Bart P. F. Rutten, Nancy L. Saccone, Sixto E. Sanchez, Dick Schijven, Soraya Seedat, Antonia V. Seligowski, Julia S. Seng, Christina M. Sheerin, Derrick Silove, Alicia K. Smith, Jordan W. Smoller, Scott R. Sponheim, Dan J. Stein, Jennifer S. Stevens, Jennifer A. Sumner, Martin H. Teicher, Wesley K. Thompson, Edward Trapido, Monica Uddin, Robert J. Ursano, Leigh Luella van den Heuvel, Miranda Van Hooff, Eric Vermetten, Christiaan H. Vinkers, Joanne Voisey, Yunpeng Wang, Zhewu Wang, Thomas Werge, Michelle A. Williams, Douglas E. Williamson, Sherry Winternitz, Christiane Wolf, Erika J. Wolf, Jonathan D. Wolff, Rachel Yehuda, Ross McD. Young, Keith A. Young, Hongyu Zhao, Lori A. Zoellner, Israel Liberzon, Kerry J. Ressler, Magali Haas, Karestan C. Koenen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Post-traumatic stress disorder (PTSD) is a common mental health problem. Here, the authors report a GWAS from the Psychiatric Genomics Consortium in which they identify two risk loci in European ancestry and one locus in African ancestry individuals
Externí odkaz:
https://doaj.org/article/d39ff05b76b746a5b312681b5db7b9fc
Autor:
Oliver Pain, Kylie P Glanville, Saskia P Hagenaars, Saskia Selzam, Anna E Fürtjes, Héléna A Gaspar, Jonathan R I Coleman, Kaili Rimfeld, Gerome Breen, Robert Plomin, Lasse Folkersen, Cathryn M Lewis
Publikováno v:
PLoS Genetics, Vol 17, Iss 5, p e1009021 (2021)
The predictive utility of polygenic scores is increasing, and many polygenic scoring methods are available, but it is unclear which method performs best. This study evaluates the predictive utility of polygenic scoring methods within a reference-stan
Externí odkaz:
https://doaj.org/article/16d89b298f4a47c48c8b77552d412603