Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jonathan R, Davey"'
Autor:
Kate T. Murphy, Kristy Swiderski, James G. Ryall, Jonathan R. Davey, Hongwei Qian, Séverine Lamon, Victoria C. Foletta, Jennifer Trieu, Annabel Chee, Suzannah J. Read, Timur Naim, Paul Gregorevic, Gordon S. Lynch
Publikováno v:
JCSM Rapid Communications, Vol 5, Iss 1, Pp 102-116 (2022)
Abstract Background Cachexia is a debilitating complication of cancer characterized by progressive wasting and weakness of skeletal muscles that reduces quality of life and can compromise survival. Many anticancer treatments, such as chemotherapy, al
Externí odkaz:
https://doaj.org/article/4b80acbe02104dee8ebddccaedd7c9ba
Autor:
Mark A. Febbraio, Darren C. Henstridge, Paul Gregorevic, Jonathan R. Davey, Hongwei Qian, Helen Ludlow, Mark P. Hedger, Martin Whitham, Melinda T. Coughlan, Sean L. McGee, Adam Hagg, Rachel E. Thomson, Emma Estevez, Kevin I. Watt
Publikováno v:
The FASEB Journal. 34:5697-5714
Type 2 diabetes (T2D) manifests from inadequate glucose control due to insulin resistance, hypoinsulinemia, and deteriorating pancreatic β-cell function. The pro-inflammatory factor Activin has been implicated as a positive correlate of severity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0425e1ab158ecfdd0433ae1985430f39
https://doi.org/10.1096/fj.201802059rrr
https://doi.org/10.1096/fj.201802059rrr
Autor:
Erik A. Richter, Zhencheng Li, Jonathan R. Davey, Kirstine N. Bojsen-Møller, Jonas R. Knudsen, Thomas E. Jensen, Carlos Henríquez-Olguín, Lykke Sylow, Lisbeth L. V. Møller, Estelle De Groote, Paul Gregorevic, Xiuqing Han, Sten Madsbad
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 6, Pp 1241-1257 (2019)
Journal of Cachexia, Sarcopenia and Muscle
Han, X, Møller, L L V, De Groote, E, Bojsen-Møller, K N, Davey, J, Henríquez-Olguin, C, Li, Z, Knudsen, J R, Jensen, T E, Madsbad, S, Gregorevic, P, Richter, E A & Sylow, L 2019, ' Mechanisms involved in follistatin-induced hypertrophy and increased insulin action in skeletal muscle ', Journal of Cachexia, Sarcopenia and Muscle, vol. 10, no. 6, pp. 1241-1257 . https://doi.org/10.1002/jcsm.12474
Journal of Cachexia, Sarcopenia and Muscle
Han, X, Møller, L L V, De Groote, E, Bojsen-Møller, K N, Davey, J, Henríquez-Olguin, C, Li, Z, Knudsen, J R, Jensen, T E, Madsbad, S, Gregorevic, P, Richter, E A & Sylow, L 2019, ' Mechanisms involved in follistatin-induced hypertrophy and increased insulin action in skeletal muscle ', Journal of Cachexia, Sarcopenia and Muscle, vol. 10, no. 6, pp. 1241-1257 . https://doi.org/10.1002/jcsm.12474
BackgroundSkeletal muscle wasting is often associated with insulin resistance. A major regulator of muscle mass is the transforming growth factor β (TGF-β) superfamily, including activin A, which causes atrophy. TGF-β superfamily ligands also nega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98dc5f6902917e89108592d7427c4451
https://doaj.org/article/dd8c8c9c3b104cf7b0bbb947b4cf7469
https://doaj.org/article/dd8c8c9c3b104cf7b0bbb947b4cf7469
Autor:
Dorit Samocha-Bonet, Mark Ziemann, Matthew J. Watt, René Koopman, Adam Hagg, Jerry R. Greenfield, Magdalene K. Montgomery, Hongwei Qian, Garron T. Dodd, Simon T. Bond, Darren C. Henstridge, Rachel E. Thomson, Paul Gregorevic, Talhah M. Salmi, Assam El-Osta, K. F. Harvey, Mark A. Febbraio, Choon Boon Sim, Kevin I. Watt, Brian G. Drew, Andrew G. Cox, Jonathan R. Davey, Rachel S. Lee, Benjamin L. Parker, Enzo R. Porrello
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Obesity is a major risk factor underlying the development of metabolic disease and a growing public health concern globally. Strategies to promote skeletal muscle metabolism can be effective to limit the progression of metabolic disease. Here, we dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2fc401ce1ea70c3f249978ef0882f2b
https://doi.org/10.1038/s41467-021-23240-7
https://doi.org/10.1038/s41467-021-23240-7
Publikováno v:
Molecular & Cellular Proteomics : MCP
Mol Cell Proteomics
Mol Cell Proteomics
Ubiquitination is a posttranslational protein modification that has been shown to have a range of effects, including regulation of protein function, interaction, localization, and degradation. We have previously shown that the muscle-specific ubiquit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88a5086222dd382a409e9eec910c431
http://europepmc.org/articles/PMC8042406
http://europepmc.org/articles/PMC8042406
Autor:
D. Donner, Rachel S. Wallace, Jarmon G Lees, Laura J. Parry, Miles J. De Blasio, Shiang Y. Lim, Amy J. Davidoff, Rebecca H. Ritchie, Hongwei Qian, Darnel Prakoso, Minh Deo, Mitchel Tate, Jeffrey R. Erickson, Darren C. Henstridge, Paul Gregorevic, John C. Chatham, Helen Kiriazis, Jonathan R. Davey
Publikováno v:
Cardiovascular research. 118(1)
Aims: The glucose-driven enzymatic modification of myocardial proteins by the sugar moiety, β-N-acetylglucosamine (O-GlcNAc), is increased in pre-clinical models of diabetes, implicating protein O-GlcNAc modification in diabetes-induced heart failur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657a8b251a8eda558612db9c64f2ddac
https://pubmed.ncbi.nlm.nih.gov/34254135
https://pubmed.ncbi.nlm.nih.gov/34254135
Publikováno v:
Molecular & Cellular Proteomics. 21:100146
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a496c40c253b08c26bd4112e802baa6
https://doi.org/10.1016/j.mcpro.2021.100146
https://doi.org/10.1016/j.mcpro.2021.100146
Autor:
Louise Cunningham, Marco Sandri, David E. James, Paul Gregorevic, Hongwei Qian, Benjamin L. Parker, Jonathan R. Davey, James G. Ryall, Kevin I. Watt, Rima Chaudhuri, Jeffrey S. Chamberlain, Vittorio Sartorelli
Publikováno v:
JCI Insight. 1
The transforming growth factor-β (TGF-β) signaling network is a critical regulator of skeletal muscle mass and function and, thus, is an attractive therapeutic target for combating muscle disease, but the underlying mechanisms of action remain unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677acadfc27e2f47b00e1b61337b0ea4
https://doi.org/10.1172/jci.insight.85477
https://doi.org/10.1172/jci.insight.85477
Autor:
Sean J. Humphrey, Jagath Reddy Junutula, Ashwini K. Mishra, David E. James, Jacqueline Stöckli, David G. Lambright, Jonathan R. Davey
Publikováno v:
Traffic. 13:1429-1441
Insulin stimulates glucose transport in adipocytes by triggering translocation of GLUT4 glucose transporters to the plasma membrane (PM) and several Rabs including Rab10 have been implicated in this process. To delineate the molecular regulation of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43d6b2bd373751ef0765977ece9a2604
https://doi.org/10.1111/j.1600-0854.2012.01397.x
https://doi.org/10.1111/j.1600-0854.2012.01397.x
Autor:
David E. James, Jacqueline Stöckli, Jonathan R. Davey, Georg Ramm, Aimin Xu, Cordula Hohnen-Behrens
Publikováno v:
Monash University
Insulin-stimulated translocation of the glucose transporter GLUT4 to the plasma membrane in muscle and fat cells depends on the phosphatidylinositide 3-kinase/Akt pathway. The downstream target AS160/TBC1D4 is phosphorylated upon insulin stimulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a567638ca68151f7b2eff50f8667eebb
https://doi.org/10.1210/me.2008-0111
https://doi.org/10.1210/me.2008-0111