Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jonathan R, Chekan"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 1548-1559 (2024)
In recent years, genome and transcriptome mining have dramatically expanded the rate of discovering diverse natural products from bacteria and fungi. In plants, this approach is often more limited due to the lack of available annotated genomes and tr
Externí odkaz:
https://doaj.org/article/db0a579b8dcd493cbe458373acbf9249
Autor:
Ignacio A. Gallardo, Daniel A. Todd, Stella T. Lima, Jonathan R. Chekan, Norman H. Chiu, Ethan Will Taylor
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 559 (2023)
Associations between dietary selenium status and the clinical outcome of many viral infections, including SARS-CoV-2, are well established. Multiple independent studies have documented a significant inverse correlation between selenium status and the
Externí odkaz:
https://doaj.org/article/0a9ec117bd634094a696cb446d2ecdf4
Autor:
Jennifer L. Cordoza, Percival Yang-Ting Chen, Linnea R. Blaustein, Stella T. Lima, Marli F. Fiore, Jonathan R. Chekan, Bradley S. Moore, Shaun M. K. McKinnie
Publikováno v:
bioRxiv
Cyclic arginine noncanonical amino acids (ncAAs) are found in several actinobacterial peptide natural products with therapeutically useful antibacterial properties. The preparation of ncAAs like enduracididine and capreomycidine currently takes multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d9a9980c6c51cf2b04fc07767e862e
https://doi.org/10.1101/2023.03.21.533663
https://doi.org/10.1101/2023.03.21.533663
Autor:
Stella T. Lima, Brigitte G. Ampolini, Ethan B. Underwood, Tyler N. Graf, Cody E. Earp, Imani C. Khedi, Michael A. Pasquale, Jonathan R. Chekan
Publikováno v:
Angewandte Chemie. 135
Cyclopeptide alkaloids are an abundant class of plant cyclopeptides with over 200 analogs described and bioactivities ranging from analgesic to antiviral. While these natural products have been known for decades, their biosynthetic basis remains uncl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e35fd221ce9ed069f438ae6c3588fe1
https://doi.org/10.1002/ange.202218082
https://doi.org/10.1002/ange.202218082
Autor:
Stella T. Lima, Brigitte G. Ampolini, Ethan B. Underwood, Tyler N. Graf, Cody E. Earp, Imani C. Khedi, Jonathan R. Chekan
Cyclopeptide alkaloids are an abundant class of plant cyclopeptides with over 200 analogs described and bioactivities ranging from analgesic to antiviral. While these natural products have been known for decades, their biosynthetic basis remains uncl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a2233d275fab4dca0efa936f807f575
https://doi.org/10.1101/2022.09.15.507631
https://doi.org/10.1101/2022.09.15.507631
Autor:
Terry R. Wright, Daniel L. Siehl, Andrew E. Robinson, Samantha Griffin, Jonathan R. Chekan, Satish K. Nair, Justin M. Lira, Yerkes Carla N, Robert M. Cicchillo
Publikováno v:
Journal of Agricultural and Food Chemistry. 69:5096-5104
Natural and modified versions of the 5-enolpyruvylshikimate-3-phosphate synthase (epsps) gene have been used to confer tolerance to the broad-spectrum herbicide glyphosate in a variety of commercial crops. The most widely utilized trait was obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cae08459876b05e544581926e00c6cc
https://doi.org/10.1021/acs.jafc.1c00439
https://doi.org/10.1021/acs.jafc.1c00439
Publikováno v:
Natural Product Reports
Covering: 2016 to 2021 With genetic information available for hundreds of thousands of organisms in publicly accessible databases, scientists have an unprecedented opportunity to meticulously survey the diversity and inner workings of life. The natur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad7dba4babc266a09a0cd0be15a45c7
https://doi.org/10.1039/d1np00032b
https://doi.org/10.1039/d1np00032b
Autor:
Taylor S. Steele, John K. Brunson, Yukari Maeno, Ryuta Terada, Andrew E. Allen, Mari Yotsu-Yamashita, Jonathan R. Chekan, Bradley S. Moore
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 6
Domoic acid (DA), the causative agent of amnesic shellfish poisoning, is produced by select organisms within two distantly related algal clades: planktonic diatoms and red macroalgae. The biosynthetic pathway to isodomoic acid A was recently solved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6e298431f7e7eff6b8dbd6f9486257
https://doi.org/10.1073/pnas.2117407119
https://doi.org/10.1073/pnas.2117407119
Autor:
Taylor S, Steele, John K, Brunson, Yukari, Maeno, Ryuta, Terada, Andrew E, Allen, Mari, Yotsu-Yamashita, Jonathan R, Chekan, Bradley S, Moore
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(6)
Domoic acid (DA), the causative agent of amnesic shellfish poisoning, is produced by select organisms within two distantly related algal clades: planktonic diatoms and red macroalgae. The biosynthetic pathway to isodomoic acid A was recently solved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72fcbb67f2234de3ab285264d6b69a90
https://pubmed.ncbi.nlm.nih.gov/35110408
https://pubmed.ncbi.nlm.nih.gov/35110408
Autor:
Jonathan R. Chekan, Shaun M. K. McKinnie, Malia L. Moore, Shane G. Poplawski, Todd P. Michael, Bradley S. Moore
Publikováno v:
Angewandte Chemie (International ed. in English), vol 58, iss 25
Angew Chem Int Ed Engl
Angew Chem Int Ed Engl
Kainic acid, the flagship member of the kainoid family of natural neurochemicals, is a widely used neuro-pharmacological agent that helped unravel the key role of ionotropic glutamate receptors, including the kainate receptor, in the central nervous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14008ae6e9f079612aba64c74eee74b3
https://doi.org/10.1002/anie.201902910
https://doi.org/10.1002/anie.201902910