Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jonathan Powlson"'
Autor:
Jonathan Powlson, Daniel Wright, Antra Zeltina, Mark Giza, Morten Nielsen, Tommy Rampling, Navin Venkatrakaman, Thomas A. Bowden, Adrian V.S. Hill, Katie J. Ewer
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2537-2545.e3 (2019)
Summary: Ebolavirus causes highly lethal hemorrhagic fever in humans. The envelope-displayed viral glycoprotein (GP) is the primary target of humoral immunity induced by natural exposure and vaccination. No T cell epitopes in the GP have been charact
Externí odkaz:
https://doaj.org/article/ebe16cc1a325464592d23c4905d28974
Autor:
Pedro M. Folegatti, Duncan Bellamy, Rachel Roberts, Jonathan Powlson, Nick J. Edwards, Catherine F. Mair, Georgina Bowyer, Ian Poulton, Celia H. Mitton, Nicky Green, Eleanor Berrie, Alison M. Lawrie, Adrian V.S. Hill, Katie J. Ewer, John Hermon-Taylor, Sarah C. Gilbert
Publikováno v:
Vaccines, Vol 7, Iss 2, p 40 (2019)
Adenovirus vectored vaccines are a highly effective strategy to induce cellular immune responses which are particularly effective against intracellular pathogens. Recombinant simian adenovirus vectors were developed to circumvent the limitations impo
Externí odkaz:
https://doaj.org/article/972193b6a1c54ddca8bc7ac33f7fdf5c
Autor:
Georgina Bowyer, Tommy Rampling, Jonathan Powlson, Richard Morter, Daniel Wright, Adrian V.S. Hill, Katie J. Ewer
Publikováno v:
Vaccines, Vol 6, Iss 3, p 50 (2018)
Immunogenicity of T cell-inducing vaccines, such as viral vectors or DNA vaccines and Bacillus Calmette-Guérin (BCG), are frequently assessed by cytokine-based approaches. While these are sensitive methods that have shown correlates of protection in
Externí odkaz:
https://doaj.org/article/b0d8d3805861473aae29e13c8708410a
Autor:
Tommy Rampling, Antra Zeltina, Morten Nielsen, Mark Giza, Jonathan Powlson, Thomas A. Bowden, Adrian V. S. Hill, Daniel B. Wright, Katie J. Ewer, Navin Venkatrakaman
Publikováno v:
Cell Reports
Cell Reports, Vol 29, Iss 9, Pp 2537-2545.e3 (2019)
Powlson, J, Wright, D, Zeltina, A, Giza, M, Nielsen, M, Rampling, T, Venkatrakaman, N, Bowden, T A, Hill, A V S & Ewer, K J 2019, ' Characterization of Antigenic MHC-Class-I-Restricted T Cell Epitopes in the Glycoprotein of Ebolavirus ', Cell Reports, vol. 29, no. 9, pp. 2537-2545.e3 . https://doi.org/10.1016/j.celrep.2019.10.105
Cell Reports, Vol 29, Iss 9, Pp 2537-2545.e3 (2019)
Powlson, J, Wright, D, Zeltina, A, Giza, M, Nielsen, M, Rampling, T, Venkatrakaman, N, Bowden, T A, Hill, A V S & Ewer, K J 2019, ' Characterization of Antigenic MHC-Class-I-Restricted T Cell Epitopes in the Glycoprotein of Ebolavirus ', Cell Reports, vol. 29, no. 9, pp. 2537-2545.e3 . https://doi.org/10.1016/j.celrep.2019.10.105
Summary Ebolavirus causes highly lethal hemorrhagic fever in humans. The envelope-displayed viral glycoprotein (GP) is the primary target of humoral immunity induced by natural exposure and vaccination. No T cell epitopes in the GP have been characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453d595c85aa7dfae6aae446d1b262ee
https://doi.org/10.1016/j.celrep.2019.10.105
https://doi.org/10.1016/j.celrep.2019.10.105
Autor:
Sarah C. Gilbert, Hill Avs., John Hermon-Taylor, Nick J. Edwards, Katie J. Ewer, Georgina Bowyer, Eleanor Berrie, P M Folegatti, C Mair, Jonathan Powlson, D Bellamy, N Green, Rachel Roberts, Ian D. Poulton, Celia Mitton, Alison M. Lawrie
Publikováno v:
Vaccines, Vol 7, Iss 2, p 40 (2019)
Vaccines
Volume 7
Issue 2
Vaccines
Volume 7
Issue 2
Adenovirus vectored vaccines are a highly effective strategy to induce cellular immune responses which are particularly effective against intracellular pathogens. Recombinant simian adenovirus vectors were developed to circumvent the limitations impo
Autor:
Benedict R. Halbroth, Eleanor Berrie, N Venkatraman, Adam A Walters, Chris J. Janse, Alison M. Lawrie, Ahmed M. Salman, Adrian V. S. Hill, Stefan Uderhardt, Ian D. Poulton, D Silman, Ronald N. Germain, Alexandra J. Spencer, Shahid M. Khan, Megan Baker, Jonathan Powlson, Anita Gola, Brian Angus, Saranya Sridhar, Katie J. Ewer, Georgina Bowyer, Rachel Roberts, D Bellamy
Publikováno v:
Science Translational Medicine, 10(460)
Despite recent advances in treatment and vector control, malaria is still a leading cause of death, emphasizing the need for an effective vaccine. The malaria life-cycle can be sub divided into three stages: the invasion and growth within liver hepat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0492e325f89178288a21bf94c97d20cf
http://hdl.handle.net/1887/96217
http://hdl.handle.net/1887/96217
Autor:
Adrian V. S. Hill, Katie J. Ewer, Georgina Bowyer, Jonathan Powlson, Daniel B. Wright, Tommy Rampling, R Morter
Publikováno v:
Vaccines, Vol 6, Iss 3, p 50 (2018)
Vaccines
Volume 6
Issue 3
Vaccines
Volume 6
Issue 3
Immunogenicity of T cell-inducing vaccines, such as viral vectors or DNA vaccines and Bacillus Calmette-Gué
rin (BCG), are frequently assessed by cytokine-based approaches. While these are sensitive methods that have shown correlates of pr
rin (BCG), are frequently assessed by cytokine-based approaches. While these are sensitive methods that have shown correlates of pr
Autor:
Katie Ewer, Tommy Rampling, Navin Venkatraman, Georgina Bowyer, Danny Wright, Teresa Lambe, Egeruan B. Imoukhuede, Ruth Payne, Sarah Katharina Fehling, Thomas Strecker, Nadine Biedenkopf, Verena Krähling, Claire M. Tully, Nick J. Edwards., Emma M. Bentley, Dhanraj Samuel, Geneviève Labbé, Jing Jin, Malick Gibani., Alice Minhinnic, Morven Wilkie, Ian Poulton, Natalie Lella, Rachel Roberts, Felicity Hartnell, Carly Bliss, Kailan Sierra-Davidson, Jonathan Powlson, Eleanor Berrie, Richard Tedder, B. Chir., Francois Roman, Iris De Ryck, Alfredo Nicosia, Nancy J. Sullivan, Daphne A. Stanley, Olivier T. Mbaya, Julie E. Ledgerwood, Richard M. Schwartz, Loredana Siani, Stefano Colloca, Antonella Folgori, Stefania Di Marco, Riccardo Cortese, Edward Wright, Stephan Becker, Barney S. Graham, Richard A. Koup, Myron M. Levine, Ariane Volkmann, Paul Chaplin, Andrew J. Pollard, Simon J. Draper, D. Phil., W. Ripley Ballou, Alison Lawrie, Sarah C. Gilbert, and Adrian V. S. Hill
BACKGROUND\ud The West African outbreak of Ebola virus disease that peaked in 2014 has caused more than 11,000 deaths. The development of an effective Ebola vaccine is a priority for control of a future outbreak.\ud \ud METHODS\ud In this phase 1 stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180dc9091c76e4ca78fdb439784cfb18
https://westminsterresearch.westminster.ac.uk/download/73fc5235cecfad936d01e4885891d2bdbd8509ccc9118034132a348b6eac7ac2/444979/nejmoa1411627.pdf
https://westminsterresearch.westminster.ac.uk/download/73fc5235cecfad936d01e4885891d2bdbd8509ccc9118034132a348b6eac7ac2/444979/nejmoa1411627.pdf