Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Jonathan P. Taylor"'
Autor:
Jonathan D. Taylor, Nathalie Barrett, Sergio Martinez Cuesta, Katelyn Cassidy, Fiona Pachl, James Dodgson, Radhika Patel, Tuula M. Eriksson, Aidan Riley, Matthew Burrell, Christin Bauer, D. Gareth Rees, Raffaello Cimbro, Andrew X. Zhang, Ralph R. Minter, James Hunt, Sandrine Legg
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Proteins can be targeted for degradation by engineering biomolecules that direct them to the eukaryotic ubiquitination machinery. For instance, the fusion of an E3 ubiquitin ligase to a suitable target binding domain creates a ‘biological
Externí odkaz:
https://doaj.org/article/82c3864e38134c29b42485f93454e6e6
Autor:
Christine Cocquyt, Jonathan C. Taylor
Publikováno v:
Plant Ecology and Evolution, Vol 157, Iss 2, Pp 149-157 (2024)
Background and aims – Actinella species from Central Africa are only rarely reported. The acid waters from many stream and small rivers in the Congo Basin form a potential environment for species of this genus. We studied several samples from the r
Externí odkaz:
https://doaj.org/article/dba76666c8d4488ebae06f43402a7d61
Publikováno v:
Plant Ecology and Evolution, Vol 157, Iss 1, Pp 88-99 (2024)
Background and aims – Diatoms from tropical Central Africa are rarely studied and documented. Waters of the Congo Basin are often acidic and thus may be dominated by diatoms from the genus Eunotia, usually found in the benthos and periphyton, but r
Externí odkaz:
https://doaj.org/article/0e83b49e27eb484d9d06b383e718f3ab
Autor:
Alice Fletcher, Dean Clift, Emma de Vries, Sergio Martinez Cuesta, Timothy Malcolm, Francesco Meghini, Raghothama Chaerkady, Junmin Wang, Abby Chiang, Shao Huan Samuel Weng, Jonathan Tart, Edmond Wong, Gerard Donohoe, Philip Rawlins, Euan Gordon, Jonathan D. Taylor, Leo James, James Hunt
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Human antigen R (HuR) is a ubiquitously expressed RNA-binding protein, which functions as an RNA regulator. Overexpression of HuR correlates with high grade tumours and poor patient prognosis, implicating it as an attractive therapeutic targ
Externí odkaz:
https://doaj.org/article/0a4a30a2a8bb41ef8d8998148778ebbb
Autor:
Michael J. Sharkey, Jonathan C. Taylor, Samer Alabed, Krit Dwivedi, Kavitasagary Karunasaagarar, Christopher S. Johns, Smitha Rajaram, Pankaj Garg, Dheyaa Alkhanfar, Peter Metherall, Declan P. O'Regan, Rob J. van der Geest, Robin Condliffe, David G. Kiely, Michail Mamalakis, Andrew J. Swift
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
IntroductionComputed tomography pulmonary angiography (CTPA) is an essential test in the work-up of suspected pulmonary vascular disease including pulmonary hypertension and pulmonary embolism. Cardiac and great vessel assessments on CTPA are based o
Externí odkaz:
https://doaj.org/article/17a2944242fa45ea935379de69712608
Autor:
Michael J. Espiritu, Jonathan K. Taylor, Christopher K. Sugai, Parashar Thapa, Nikolaus M. Loening, Emma Gusman, Zenaida G. Baoanan, Michael H. Baumann, Jon-Paul Bingham
Publikováno v:
Marine Drugs, Vol 21, Iss 2, p 61 (2023)
χ-Conotoxins are known for their ability to selectively inhibit norepinephrine transporters, an ability that makes them potential leads for treating various neurological disorders, including neuropathic pain. PnID, a peptide isolated from the venom
Externí odkaz:
https://doaj.org/article/ae427a0baa8a42f0ad484d5d02a4dc23
Autor:
Jonathan M. Taylor, Isabel M. Morris
Publikováno v:
Infrastructures, Vol 7, Iss 12, p 173 (2022)
Determining the material properties and existing capacity of concrete infrastructure using nondestructive techniques is challenging due to evolving design requirements, unknown as-built conditions, and ongoing maintenance and deterioration. Concrete
Externí odkaz:
https://doaj.org/article/9cd06eca2d4e4d2ca5968b4d57924a26
Autor:
Jonathan M. Taylor, Carl J. Nelson, Finnius A. Bruton, Aryan Kaveh, Charlotte Buckley, Carl S. Tucker, Adriano G. Rossi, John J. Mullins, Martin A. Denvir
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Imaging heart development is challenging due to constant tissue movement and changing physical landmarks. Here the authors present an algorithm capable of maintaining phase-locked imaging throughout a 24 hour timespan, enabling long term timelapse im
Externí odkaz:
https://doaj.org/article/178169f074c049959cd3251b5dd86533
Autor:
Unė G. Būtaitė, Graham M. Gibson, Ying-Lung D. Ho, Mike Taverne, Jonathan M. Taylor, David B. Phillips
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Optical tweezing with intense lasers can be harmful to biological specimens and limits the types of materials that can be trapped. Here, the authors demonstrate an indirect optical trapping approach which uses hydrodynamic forces to exert nanoscale-p
Externí odkaz:
https://doaj.org/article/eb3ceae5935d40feb41a9c334e639d61
Autor:
Daniel H. Mai, Jonathan S. Taylor-Fishwick, William Sherred-Smith, Anthony Pang, Justin Yaworsky, Sean Whitty, Alex Lafever, Cody Mcilvain, Mark Schmitt, Michelle Rogers-Johnson, April Pace, Anca D. Dobrian
Publikováno v:
MedEdPORTAL, Vol 16 (2020)
Introduction Evidence-based medicine (EBM) is pivotal in shaping patient care, yet it is challenging to incorporate into undergraduate medical education (UME) due to a lack of dedicated resources within the preclinical curriculum. To address this cha
Externí odkaz:
https://doaj.org/article/68ab258abd6b47528f9b35378140626b