Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Jonathan P. Katz"'
KLF5 and p53 comprise an incoherent feed-forward loop directing cell-fate decisions following stress
Autor:
Yizeng Yang, Dharmendra Bhargava, Xiao Chen, Taicheng Zhou, Gizem Dursuk, Wenpeng Jiang, Jinshen Wang, Zhen Zong, Sharyn I. Katz, Gwen A. Lomberk, Raul A. Urrutia, Jonathan P. Katz
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-10 (2023)
Abstract In response to stress, cells make a critical decision to arrest or undergo apoptosis, mediated in large part by the tumor suppressor p53. Yet the mechanisms of these cell fate decisions remain largely unknown, particularly in normal cells. H
Externí odkaz:
https://doaj.org/article/ec7f0cfa3b1b4e0b99fa62ec85368f3d
Autor:
Lei Li, Rui Zhu, Honghong Zhou, Chun‐Ping Cui, Xiao Yu, Yuhao Liu, Yin Yin, Yang Li, Riyue Feng, Jonathan P. Katz, Yahui Zhao, Yun Zhang, Lingqiang Zhang, Zhihua Liu
Publikováno v:
Advanced Science, Vol 10, Iss 16, Pp n/a-n/a (2023)
Abstract β‐TrCP is an E3 ubiquitin ligase that plays important roles in multiple human cancers including esophageal squamous cell carcinoma (ESCC). Analysis of ESCC patient samples reveal that only protein level but not transcript level of β‐Tr
Externí odkaz:
https://doaj.org/article/b242253180974424bb1c215e632f7a0b
Autor:
Abhishek Dutta, Shrikrishna Bhagat, Swastika Paul, Jonathan P. Katz, Debomita Sengupta, Dharmendra Bhargava
Publikováno v:
Vaccines, Vol 11, Iss 6, p 1028 (2023)
Neutrophils are the most abundant immune cells and make up about 70% of white blood cells in human blood and play a critical role as the first line of defense in the innate immune response. They also help regulate the inflammatory environment to prom
Externí odkaz:
https://doaj.org/article/a782c241548a4f7eaa39bcd058663906
Autor:
Mitsuteru Natsuizaka, Kelly A. Whelan, Shingo Kagawa, Koji Tanaka, Veronique Giroux, Prasanna M. Chandramouleeswaran, Apple Long, Varun Sahu, Douglas S. Darling, Jianwen Que, Yizeng Yang, Jonathan P. Katz, E. Paul Wileyto, Devraj Basu, Yoshiaki Kita, Shoji Natsugoe, Seiji Naganuma, Andres J. Klein-Szanto, J. Alan Diehl, Adam J. Bass, Kwok-Kin Wong, Anil K. Rustgi, Hiroshi Nakagawa
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Notch receptors can exert different roles in cancer. In this manuscript, the authors reveal that Notch1 activation and EMT promote tumor initiation and cancer cell heterogeneity in squamous cell carcinoma, while the repression of Notch3 by ZEB1 limit
Externí odkaz:
https://doaj.org/article/6f8691ad6d324ab0a967f60181be89c5
Autor:
Mingang Xu, Jeremy Horrell, Melinda Snitow, Jiawei Cui, Heather Gochnauer, Camille M. Syrett, Staci Kallish, John T. Seykora, Fei Liu, Dany Gaillard, Jonathan P. Katz, Klaus H. Kaestner, Brooke Levin, Corinne Mansfield, Jennifer E. Douglas, Beverly J. Cowart, Michael Tordoff, Fang Liu, Xuming Zhu, Linda A. Barlow, Adam I. Rubin, John A. McGrath, Edward E. Morrisey, Emily Y. Chu, Sarah E. Millar
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-21 (2017)
Human WNT10A mutations are associated with dental defects and adult onset ectodermal dysplasia. Xuet al. show that WNT10A-activated ß-catenin plays dual roles in adult epithelial progenitor proliferation and differentiation by complexing with KLF4 i
Externí odkaz:
https://doaj.org/article/155ddb06076c415fa01075d340f6d738
Autor:
Mary Ann S. Crissey, Rong-Jun Guo, Franz Fogt, Hong Li, Jonathan P. Katz, Debra G. Silberg, Eun Ran Suh, John P. Lynch
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 1, Pp 8-19 (2008)
The Caudal-related homeobox genes Cdx1 and Cdx2 are intestine-specific transcription factors that regulate differentiation of intestinal cell types. Previously, we have shown Cdx1 to be antiproliferative and to promote cell differentiation. However,
Externí odkaz:
https://doaj.org/article/1a1293dd3c814e0f874ea7227c13ff0e
Autor:
Vincent W. Yang, Klaus H. Kaestner, Jonathan P. Katz, Mandayam O. Nandan, Beth B. McConnell, Amr M. Ghaleb
Supplementary Figure 3 from Haploinsufficiency of Krüppel-Like Factor 4 Promotes Adenomatous Polyposis Coli–Dependent Intestinal Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8e4a30e2f27bf55accffcdfb80ff8a
https://doi.org/10.1158/0008-5472.22367760.v1
https://doi.org/10.1158/0008-5472.22367760.v1
Autor:
Jonathan P. Katz, Antonia R. Sepulveda, Abha Goyal, Noel Victor, Janelle Billig, Marie-Pier Tetreault, Hiroshi Nakagawa, Yizeng Yang
PDF file - 300K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7885f8498ac06cfd69576b2d15c0a7be
https://doi.org/10.1158/0008-5472.22389717
https://doi.org/10.1158/0008-5472.22389717
Autor:
Jonathan P. Katz, Antonia R. Sepulveda, Abha Goyal, Noel Victor, Janelle Billig, Marie-Pier Tetreault, Hiroshi Nakagawa, Yizeng Yang
PDF file - 132K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b4a49fc72584a40a5eac56a922173e
https://doi.org/10.1158/0008-5472.22389711.v1
https://doi.org/10.1158/0008-5472.22389711.v1
Autor:
Jonathan P. Katz, Antonia R. Sepulveda, Abha Goyal, Noel Victor, Janelle Billig, Marie-Pier Tetreault, Hiroshi Nakagawa, Yizeng Yang
PDF file - 317K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877d4eaafe19f964ba012a4e28e644d3
https://doi.org/10.1158/0008-5472.22389723
https://doi.org/10.1158/0008-5472.22389723