Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Jonathan P. Jacobs"'
Publikováno v:
Gut and Liver, Vol 18, Iss 4, Pp 611-620 (2024)
Background/Aims: While DNA methylation and gastric microbiome are each associated with gastric cancer (GC), their combined role in predicting GC remains unclear. This study investigated the potential of a combined DNA methylation and gastric microbio
Externí odkaz:
https://doaj.org/article/dbf3dda02f124678b7bef454cb5639d4
Autor:
Kristofer Andréasson, Tor Olofsson, Venu Lagishetty, Zaid Alrawi, Eline Klaassens, Savanne Holster, Roger Hesselstrand, Jonathan P. Jacobs, Johan K. Wallman, Elizabeth R. Volkmann
Publikováno v:
ACR Open Rheumatology, Vol 6, Iss 7, Pp 421-427 (2024)
Objective Emerging research suggests that rheumatoid arthritis (RA) is associated with intestinal dysbiosis. This prospective pilot study evaluates changes in intestinal microbial composition in patients with RA initiating treatment with either metho
Externí odkaz:
https://doaj.org/article/0552ee83a31f4bd6875402d1c0c2b9a6
Autor:
Dayoon Kwon, Keren Zhang, Kimberly C. Paul, Aline D. Folle, Irish Del Rosario, Jonathan P. Jacobs, Adrienne M. Keener, Jeff M. Bronstein, Beate Ritz
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract It has been suggested that gut microbiota influence Parkinson’s disease (PD) via the gut–brain axis. Here, we examine associations between diet and gut microbiome composition and its predicted functional pathways in patients with PD. We
Externí odkaz:
https://doaj.org/article/84113f7bdfa74f85b1afd7f29a4c6518
Autor:
Keren Zhang, Kimberly Paul, Jonathan P. Jacobs, Myles G. Cockburn, Jeff M. Bronstein, Irish del Rosario, Beate Ritz
Publikováno v:
Environmental Health, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Organophosphorus pesticides (OP) have been associated with various human health conditions. Animal experiments and in-vitro models suggested that OP may also affect the gut microbiota. We examined associations between ambient chro
Externí odkaz:
https://doaj.org/article/18c98581b243464a85c9660d9c7966d4
Autor:
Simer Shera, William Katzka, Julianne C. Yang, Candace Chang, Nerea Arias-Jayo, Venu Lagishetty, Anna Balioukova, Yijun Chen, Erik Dutson, Zhaoping Li, Emeran A. Mayer, Joseph R. Pisegna, Claudia Sanmiguel, Shrey Pawar, David Zhang, Madelaine Leitman, Laura Hernandez, Jonathan P. Jacobs, Tien S. Dong
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionMetabolic dysfunction-associated steatotic liver disease (MASLD) affects nearly 25% of the population and is the leading cause for liver-related mortality. Bariatric surgery is a well-known treatment for MASLD and obesity. Understanding t
Externí odkaz:
https://doaj.org/article/35e6a0fbea9f49eb9c6472879c31f603
Autor:
Xin Ye, Shubhamoy Ghosh, Bo-Chul Shin, Amit Ganguly, Liesbeth Maggiotto, Jonathan P. Jacobs, Sherin U. Devaskar
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionSerotonin (5-HT) is critical for neurodevelopment and the serotonin transporter (SERT) modulates serotonin levels. Perturbed prenatal and postnatal dietary exposures affect the developing offspring predisposing to neurobehavioral disorder
Externí odkaz:
https://doaj.org/article/719f5033147341eca5139c60f310502c
Autor:
Jonathan P. Jacobs, Martin L. Lee, David J. Rechtman, Adam K. Sun, Chloe Autran, Victoria Niklas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Human milk contains over 200 distinct oligosaccharides, which are critical to shaping the developing neonatal gut microbiome. To investigate whether a complex mixture of human milk oligosaccharides (HMOs) would similarly modulate the adult g
Externí odkaz:
https://doaj.org/article/f49c11d1db3b448e8e310b999cdec6a4
Autor:
Tien S. Dong, William Katzka, Julianne C. Yang, Candace Chang, Nerea Arias-Jayo, Venu Lagishetty, Anna Balioukova, Yijun Chen, Erik Dutson, Zhaoping Li, Emeran A. Mayer, Joseph R. Pisegna, Claudia Sanmiguel, Jonathan P. Jacobs
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTBariatric surgery remains a potent therapy for nonalcoholic fatty liver disease (NAFLD), but its inherent risk and eligibility requirement limit its adoption. Therefore, understanding how bariatric surgery improves NAFLD is paramount to devel
Externí odkaz:
https://doaj.org/article/b876c87bf7a54fe1bead15eb9892cf89
Autor:
Jonathan P. Jacobs, Venu Lagishetty, Megan C. Hauer, Jennifer S. Labus, Tien S. Dong, Ryan Toma, Momchilo Vuyisich, Bruce D. Naliboff, Jeffrey M. Lackner, Arpana Gupta, Kirsten Tillisch, Emeran A. Mayer
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-18 (2023)
Abstract Background Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is thought to involve alterations in the gut microbiome, but robust microbial signatures have been challenging to identify. As prior studies have primarily
Externí odkaz:
https://doaj.org/article/b494a1d45506496484c5c0afc24609e1
Autor:
Jun Gong, Shant Thomassian, Sungjin Kim, Gillian Gresham, Natalie Moshayedi, Jason Y. Ye, Julianne C. Yang, Jonathan P. Jacobs, Simon Lo, Nick Nissen, Srinivas Gaddam, Mourad Tighiouart, Arsen Osipov, Andrew Hendifar
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract In this phase I dose-escalation trial, we assess the maximum tolerated dose (MTD) of Bermekimab in combination with Nanoliposomal Irinotecan (Nal-Iri) and 5-Fluorouracil/Folinic Acid (5-FU/FA). Secondarily, we investigate effects on weight,
Externí odkaz:
https://doaj.org/article/e263745a6ab941d78e370e228fec8e54