Cerebral Lactate Dynamics Across Sleep/Wake Cycles

Autor: Michael J Rempe, Jonathan P Wisor

Publikováno v: Frontiers in Computational Neuroscience, Vol 8 (2015)

Cerebral metabolism varies dramatically as a function of sleep state. Brain concentration of lactate, the end product of glucose utilization via glycolysis, varies as a function of sleep state, and like slow wave activity (SWA) in the electroencephal

Externí odkaz: https://doaj.org/article/8e0b14003e864818ba035672e26d8432

Molecular and anatomical signatures of sleep deprivation in the mouse brain

Autor: Carol L Thompson, Jonathan P Wisor, Chang-Kyu Lee, Sayan D Pathak, Dmitry Gerashchenko, Kimberly A Smith, Shanna R Fischer, Chihchau L Kuan, Susan M Sunkin, Lydia L Ng, Christopher Lau, Mike Hawrylycz, Allan R Jones, Thomas Kilduff, Edward S Lein

Publikováno v: Frontiers in Neuroscience, Vol 4 (2010)

Sleep deprivation (SD) leads to a suite of cognitive and behavioral impairments, and yet the molecular consequences of SD in the brain are poorly understood. Using a systematic immediate-early gene mapping to detect neuronal activation, the consequen

Externí odkaz: https://doaj.org/article/fe125b5a6c004614aac265269d4c1310

Multi-Modal Regulation of Circadian Physiology by Interactive Features of Biological Clocks

Autor: Yool Lee, Jonathan P. Wisor

Publikováno v: Biology, Vol 11, Iss 1, p 21 (2021)

The circadian clock is a fundamental biological timing mechanism that generates nearly 24 h rhythms of physiology and behaviors, including sleep/wake cycles, hormone secretion, and metabolism. Evolutionarily, the endogenous clock is thought to confer

Externí odkaz: https://doaj.org/article/b181f57c32b04fff928cf52b94be6400

Diurnal changes in perineuronal nets and parvalbumin neurons in the rat medial prefrontal cortex

Autor: Travis E. Brown, Deborah M. Hegarty, John H. Harkness, Jonathan P. Wisor, Ariel A. Di Nardo, Priyanka N. Bushana, Angela E. Gonzalez, Sue A. Aicher, Alain Prochiantz, Barbara A. Sorg, Emily T. Jorgensen

Publikováno v: Brain Structure and Function
Brain Structure and Function, Springer Verlag, 2021, 226, pp.1135-1153. ⟨10.1007/s00429-021-02229-4⟩
Brain Struct Funct
Brain Structure and Function, 2021, 226, pp.1135-1153. ⟨10.1007/s00429-021-02229-4⟩

Perineuronal nets (PNNs) surrounding fast-spiking, parvalbumin (PV) inhibitory interneurons are vital for providing excitatory:inhibitory balance within cortical circuits, and this balance is impaired in disorders such as schizophrenia, autism spectr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87df43d7eb19ab7e0384523f0c925314
https://doi.org/10.1101/2020.10.25.354134

Sleep State Dependence of Optogenetically evoked Responses in Neuronal Nitric Oxide Synthase-positive Cells of the Cerebral Cortex

Autor: Michelle A. Schmidt, Dmitry Gerashchenko, Michele E. Moore, Mark R. Zielinski, Jonathan P. Wisor

Publikováno v: Neuroscience. 379:189-201

Slow-wave activity (SWA) in the electroencephalogram during slow-wave sleep (SWS) varies as a function of sleep-wake history. A putative sleep-active population of neuronal nitric oxide synthase (nNOS)-containing interneurons in the cerebral cortex,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5ea7b7ea6a2c0f27c03d241f8a7fc0
https://doi.org/10.1016/j.neuroscience.2018.02.006