Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Jonathan P Richardson"'
Autor:
Junyan Liu, Hubertine M E Willems, Emily A Sansevere, Stefanie Allert, Katherine S Barker, David J Lowes, Andrew C Dixson, Zhenbo Xu, Jian Miao, Christian DeJarnette, Helene Tournu, Glen E Palmer, Jonathan P Richardson, Francisco N Barrera, Bernhard Hube, Julian R Naglik, Brian M Peters
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009884 (2021)
Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida albicans, results in significant quality-of-life issues for women worldwide. Candidalysin, a toxin derived from a polypeptide (Ece1p) encoded by the ECE1 gene, play
Externí odkaz:
https://doaj.org/article/b3e2ce06c5484147bdbc2ffbdee60a64
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008975 (2020)
Externí odkaz:
https://doaj.org/article/5412ce44d5154f6f99b2b87ecb1a6a69
Autor:
Don N. Wickramasinghe, Claire M. Lyon, Sejeong Lee, Olivia W. Hepworth, Emily L. Priest, Corinne Maufrais, Adam P. Ryan, Emmanuelle Permal, Derek Sullivan, Brenda A. McManus, Bernhard Hube, Geraldine Butler, Christophe d'Enfert, Julian R. Naglik, Jonathan P. Richardson
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Candida albicans causes millions of mucosal infections in humans annually. Hyphal overgrowth on mucosal surfaces is frequently associated with tissue damage caused by candidalysin, a secreted peptide toxin that destabilizes the plasma membra
Externí odkaz:
https://doaj.org/article/3903d3d7c6d0456c8be1eb3b6dc95bad
Autor:
Jamie A Greig, Ian M Sudbery, Jonathan P Richardson, Julian R Naglik, Yue Wang, Peter E Sudbery
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004630 (2015)
The opportunistic human fungal pathogen, Candida albicans, undergoes morphological and transcriptional adaptation in the switch from commensalism to pathogenicity. Although previous gene-knockout studies have identified many factors involved in this
Externí odkaz:
https://doaj.org/article/846d535c67e340c5a4c64b412dfb7735
Publikováno v:
PLoS Pathogens, Vol 10, Iss 8, p e1004257 (2014)
Externí odkaz:
https://doaj.org/article/d8255a697ae84358bd7d2f39b5a8e92e
Autor:
Marie-Claude Addor, David Baud, Maya Berlin, Alice Panchaud, Thierry Buclin, François R Girardin, Ursula Winterfeld, Corinna Weber-Schoendorfer, Orna Diav-Citrin, Faiza Lamine, Kim Dao, Svetlana Shechtman, Reem Hegla Murad, Ariela Hazan, Jonathan L Richardson, Georgios Eleftheriou, Valentin Rousson, Leonore Diezi, David Haefliger, Ana Paula Simões-Wüst
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Objectives Glucagon-like peptide 1 receptor agonists (GLP1-RA) are indicated for the treatment of type 2 diabetes and more recently for weight loss. The aim of this study was to assess the risks associated with GLP1-RA exposure during early pregnancy
Externí odkaz:
https://doaj.org/article/0d9228cc67e8424b806167a253009ff7
Autor:
Yifan Wu, Shuqi Du, Lynn H. Bimler, Kelsey E. Mauk, Léa Lortal, Nessim Kichik, James S. Griffiths, Radim Osicka, Lizhen Song, Katherine Polsky, Lydia Kasper, Peter Sebo, Jill Weatherhead, J. Morgan Knight, Farrah Kheradmand, Hui Zheng, Jonathan P. Richardson, Bernhard Hube, Julian R. Naglik, David B. Corry
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113240- (2023)
Summary: The fungal pathogen Candida albicans is linked to chronic brain diseases such as Alzheimer’s disease (AD), but the molecular basis of brain anti-Candida immunity remains unknown. We show that C. albicans enters the mouse brain from the blo
Externí odkaz:
https://doaj.org/article/c973f39dfee7477fac57548342be679b
Autor:
Jonathan P. Richardson
Publikováno v:
Pathogens, Vol 11, Iss 4, p 459 (2022)
Fungal infections kill ~1 [...]
Externí odkaz:
https://doaj.org/article/5960352da414482a82f720ac4157fd76
Autor:
Jonathan L. Richardson, Georgianna Silveira, Ivanna Soto Medrano, A. Z. Arietta, Carol Mariani, Arsinoê C. Pertile, Ticiana Carvalho Pereira, James E. Childs, Albert I. Ko, Federico Costa, Adalgisa Caccone
Publikováno v:
Frontiers in Ecology and Evolution, Vol 7 (2019)
Rats thrive in human-dominated landscapes and have expanded to a near global distribution. Norway rats (Rattus norvegicus) contaminate food, damage infrastructure, and are reservoirs for zoonotic pathogens that cause human diseases. To limit these ne
Externí odkaz:
https://doaj.org/article/2681b3d528964ceaadac1f6031e6eb6d
Autor:
Jemima Ho, Don N. Wickramasinghe, Spyridoula-Angeliki Nikou, Bernhard Hube, Jonathan P. Richardson, Julian R. Naglik
Publikováno v:
Cells, Vol 9, Iss 3, p 699 (2020)
Host released alarmins and antimicrobial peptides (AMPs) are highly effective as antifungal agents and inducers. Whilst some are expressed constitutively at mucosal tissues, the primary site of many infections, others are elicited in response to path
Externí odkaz:
https://doaj.org/article/ec668f7636e94b7ca8c888cc55f436a6