Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jonathan P, Segal"'
Autor:
Shahed Kamal, Sheng Wei Lo, Samantha McCall, Beverly Rodrigues, Andrew H. Tsoi, Jonathan P. Segal
Publikováno v:
Biologics, Vol 4, Iss 2, Pp 177-186 (2024)
Background: Janus kinase (JAK) inhibitors represent a novel class of oral therapies showing efficacy in treating ulcerative colitis (UC) and Crohn’s disease (CD), challenging conventional treatment paradigms. Summary: This review provides an overvi
Externí odkaz:
https://doaj.org/article/1716a5aa3a404f73bc4f5652574fdebb
Autor:
Anuj Bohra, Declan J Connoley, Danny Con, Jonathan P Segal, Olga Niewiadomski, Abhinav Vasudevan, Daniel R Van Langenberg, Numan Kutaiba
Publikováno v:
Intestinal Research, Vol 22, Iss 2, Pp 152-161 (2024)
Background/Aims Assessment of quality of magnetic resonance enterography (MRE) in small bowel Crohn’s disease (CD) activity evaluation has received little attention. We assessed the impact of bowel distention and motion artifact on MRE activity ind
Externí odkaz:
https://doaj.org/article/7c8aa4d5179045f69c8138f3e4c072f0
Autor:
Shahed Kamal, Jonathan P. Segal
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Externí odkaz:
https://doaj.org/article/38ff2e7dc44844be86c9aca4b3fb9492
Autor:
Jonathan P Segal, Mayur Garg, Miles P Sparrow, Gareth J Walker, Ashish Srinivasan, Peter De Cruz, Desmond Chee, Alex Boussioutas, Robert V Bryant, Georgina Hold, Gregory T Moore, Susan J Connor, Robert D Little, Mark G Ward, Jo McKenzie, Patrick Hilley, Robert B Gilmore, Manjeet Sandhu, Daniel Saitta, Elizabeth Chow, Lena Thin, Kate Lynch, Jane Andrews, Yoon K An, Emily K Wright
Publikováno v:
BMJ Open, Vol 14, Iss 7 (2024)
Introduction A substantial proportion of patients with inflammatory bowel disease (IBD) on intravenous infliximab require dose intensification. Accessing additional intravenous infliximab is labour-intensive and expensive, depending on insurance and
Externí odkaz:
https://doaj.org/article/c6f1e2d43a834509bfe7e3af4a9f737f
Autor:
Anuj Bohra, Diana Lewis, Jonathan P Segal, Abhinav Vasudevan, Daniel R Van Langenberg, Olga Niewiadomski
Publikováno v:
JGH Open, Vol 7, Iss 12, Pp 966-973 (2023)
Abstract Background and Aim Capsule endoscopy allows the direct visualization of the small bowel. We examined the diagnostic utility of a new modality, namely panenteric Crohn's capsule endoscopy (CE), in detecting active small‐bowel Crohn's diseas
Externí odkaz:
https://doaj.org/article/07cbc023739f428ca89a7c8686765274
Autor:
Gurtej Singh, Clarissa Rentsch, William Beattie, Britt Christensen, Finlay Macrae, Jonathan P. Segal
Publikováno v:
Diagnostics, Vol 14, Iss 18, p 2030 (2024)
Background: Pathological reactivation of latent Cytomegalovirus (CMV) is triggered by inflammation and immunosuppression; both present in the pathogenesis and treatment of Inflammatory Bowel Disease (IBD). Whether CMV reactivation is associated with
Externí odkaz:
https://doaj.org/article/b170cee266bf4e02be08ed92363b3dd3
Autor:
Maram Alenzi, Tamar Schildkraut, Imogen Hartley, Sarit Badiani, Nik Sheng Ding, Vikram Rao, Jonathan P. Segal
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Restorative proctocolectomy with ileal pouch-anal anastomosis is a treatment option for patients with refractory ulcerative colitis. Pouchitis is the most common complication, representing a spectrum of diseases ranging from acute antibiotic-responsi
Externí odkaz:
https://doaj.org/article/c149944f2b374b07b7a7dbf03112fbd8
Autor:
Anuj Bohra, Nicholas Batt, Krishneel Dutt, Diana Lewis, Jonathan P. Segal, Olga Newiadomski, Abhinav Vasudevan, Daniel R. Van Langenberg
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Background: Faecal biomarkers are increasingly utilized for disease assessment in inflammatory bowel disease (IBD). Objectives: To characterize the relative and combined accuracy of faecal calprotectin (FC) and faecal immunochemical testing (FIT) for
Externí odkaz:
https://doaj.org/article/36651ba75e764d77a90ca57ddf556a70
Autor:
Robert Gilmore, Sheng W. Lo, Rachael Cheong, Syeda Tahiya Karim, Deborah Farrah, Soleiman Kashkooli, Jonathan P. Segal, Mayur Garg
Publikováno v:
JGH Open, Vol 7, Iss 7, Pp 482-486 (2023)
Abstract Background and Aim Acute severe ulcerative colitis (ASUC) remains a significant cause of morbidity and healthcare utilization. This study aimed to characterize the total healthcare costs of ASUC, explore factors associated with significant c
Externí odkaz:
https://doaj.org/article/8b5e5390a47e4a6cbaff93de9187eef3
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3256 (2023)
Obesity is prevalent in the inflammatory bowel disease (IBD) population, particularly in newly developed countries where both IBD and obesity in the general population are on the rise. The role of obesity in the pathogenesis of IBD was entertained bu
Externí odkaz:
https://doaj.org/article/ea434223460e40719df7e1d652d94b3a